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Article

Empirical Modelling of Hydrodynamic Effects on Starch Nanoparticles Precipitation in a Spinning Disc Reactor

School of Engineering, Merz Court, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK
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Nanomaterials 2020, 10(11), 2202; https://doi.org/10.3390/nano10112202
Received: 30 September 2020 / Revised: 26 October 2020 / Accepted: 30 October 2020 / Published: 4 November 2020
Empirical correlations have been developed to relate experimentally determined starch nanoparticle size obtained in a solvent–antisolvent precipitation process with key hydrodynamic parameters of a spinning disc reactor (SDR). Three different combinations of dimensionless groups including a conventional Reynolds number (Re), rotational Reynolds number (Reω) and Rossby number (Ro) have been applied in individual models for two disc surfaces (smooth and grooved) to represent operating variables affecting film flow such as liquid flowrate and disc rotational speed, whilst initial supersaturation (S) has been included to represent varying antisolvent concentrations. Model 1 featuring a combination of Re, Reω and S shows good agreement with the experimental data for both the grooved and smooth discs. For the grooved disc, Re has a greater impact on particle size, whereas Reω is more influential on the smooth disc surface, the difference likely being due to the passive mixing induced by the grooves irrespective of the magnitude of the disc speed. Supersaturation has little impact on particle size within the limited initial supersaturation range studied. Model 2 which characterises both flow rate and disc rotational speed through Ro alone and combined with Re was less accurate in predicting particle size due to several inherent limitations. View Full-Text
Keywords: spinning disc reactor; nanoparticles; solvent–antisolvent precipitation; empirical model; Reynolds number; rotational Reynolds number; Rossby number spinning disc reactor; nanoparticles; solvent–antisolvent precipitation; empirical model; Reynolds number; rotational Reynolds number; Rossby number
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MDPI and ACS Style

Sana, S.; Zivkovic, V.; Boodhoo, K. Empirical Modelling of Hydrodynamic Effects on Starch Nanoparticles Precipitation in a Spinning Disc Reactor. Nanomaterials 2020, 10, 2202. https://doi.org/10.3390/nano10112202

AMA Style

Sana S, Zivkovic V, Boodhoo K. Empirical Modelling of Hydrodynamic Effects on Starch Nanoparticles Precipitation in a Spinning Disc Reactor. Nanomaterials. 2020; 10(11):2202. https://doi.org/10.3390/nano10112202

Chicago/Turabian Style

Sana, Sahr, Vladimir Zivkovic, and Kamelia Boodhoo. 2020. "Empirical Modelling of Hydrodynamic Effects on Starch Nanoparticles Precipitation in a Spinning Disc Reactor" Nanomaterials 10, no. 11: 2202. https://doi.org/10.3390/nano10112202

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