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Open AccessReview

Biomechanical and Clinical Effect of Patient-Specific or Customized Knee Implants: A Review

by Jin-Ah Lee 1,†, Yong-Gon Koh 2,† and Kyoung-Tak Kang 1,*
Department of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seoul 03722, Korea
Department of Orthopaedic Surgery, Yonsei Sarang Hospital, 10 Hyoryeong-ro, Seocho-gu, Seoul 06698, Korea
Author to whom correspondence should be addressed.
J.-A.L. and Y.-G.K. contributed equally to this work and should be considered co-first authors.
J. Clin. Med. 2020, 9(5), 1559;
Received: 4 May 2020 / Revised: 13 May 2020 / Accepted: 15 May 2020 / Published: 21 May 2020
(This article belongs to the Special Issue State-of-the-Art Research on Hip and Knee Arthroplasty)
(1) Background: Although knee arthroplasty or knee replacement is already an effective clinical treatment, it continues to undergo clinical and biomechanical improvements. For an increasing number of conditions, prosthesis based on an individual patient’s anatomy is a promising treatment. The aims of this review were to evaluate the clinical and biomechanical efficacy of patient-specific knee prosthesis, explore its future direction, and summarize any published comparative studies. (2) Methods: We searched the PubMed, MEDLINE, Embase, and Scopus databases for articles published prior to 1 February 2020, with the keywords “customized knee prosthesis” and “patient-specific knee prosthesis”. We excluded patient-specific instrument techniques. (3) Results: Fifty-seven articles met the inclusion criteria. In general, clinical improvement was greater with a patient-specific knee prosthesis than with a conventional knee prosthesis. In addition, patient-specific prosthesis showed improved biomechanical effect than conventional prosthesis. However, in one study, patient-specific unicompartmental knee arthroplasty showed a relatively high rate of aseptic loosening, particularly femoral component loosening, in the short- to medium-term follow-up. (4) Conclusions: A patient-specific prosthesis provides a more accurate resection and fit of components, yields significant postoperative improvements, and exhibits a high level of patient satisfaction over the short to medium term compared with a conventional prosthesis. However, the tibial insert design of the current patient-specific knee prosthesis does not follow the tibial plateau curvature. View Full-Text
Keywords: patient-specific; knee joint; customized implant; total knee replacement patient-specific; knee joint; customized implant; total knee replacement
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Lee, J.-A.; Koh, Y.-G.; Kang, K.-T. Biomechanical and Clinical Effect of Patient-Specific or Customized Knee Implants: A Review. J. Clin. Med. 2020, 9, 1559.

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