Endothelin-1 Serum Concentration is Lower in Children and Adolescents with High Myopia, a Preliminary Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Measurements
2.3. Statistical Methods
3. Results
4. Discussion
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Parameter | High Myopia Patients | Control Group | p Values |
---|---|---|---|
Number, n | 57 | 29 | |
Age, years | 14 (13; 16) | 14 (11; 15) | 0.181 |
Gender (female/male), n (%) | 31 (54)/26 (46) | 17 (59)/12 (41) | 0.709 |
Age group (≤13/>13 year), n (%) | 23 (40)/34 (60) | 13 (45)/16 (55) | 0.691 |
Endothelin-1, pg/mL | 1.47 (0.91; 1.87) | 1.94 (1.1; 2.69) | 0.005 |
Features | High Myopia Patients, n = 57 |
---|---|
Visual acuity of right eye | 1.0 (0.7; 1.0) |
Visual acuity of left eye | 0.8 (0.6; 1.0) |
Refractive error of right eye, D | −6.8 (−8.6; −6) |
Refractive error of left eye, D | −6.8 (−9.5; −6) |
Axial length of right eye, mm | 25.9 (25.3; 26.6) |
Axial length of left eye, mm | 25.8 (25.3; 26.6) |
Peripheral chorioretinal atrophy, yes/no, n (%) | 11 (19)/46 (81) |
Parameter | High Myopia Patients | Control Group | |
---|---|---|---|
Axial Length of Eye | |||
>26 mm | ≤26 mm | ||
Number, n | 29 | 28 | 29 |
Gender (female/male), n (%) | 13 (45)/16 (55) | 18 (64)/10 (36) | 17 (59)/12 (41) |
Age group (≤13/>13 year), n (%) | 12 (41)/17 (59) | 11 (39)/17 (61) | 13 (45)/16 (55) |
Endothelin-1, pg/mL | 1.23 (0.78; 1.72) a,b | 1.61 (1.12; 2.04) | 1.94 (1.1; 2.69) |
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Powierza, K.; Żelazowska-Rutkowska, B.; Sawicka-Powierza, J.; Mikołuć, B.; Urban, B.; Zaremba, W.; Cylwik, B.; Bakunowicz-Łazarczyk, A. Endothelin-1 Serum Concentration is Lower in Children and Adolescents with High Myopia, a Preliminary Study. J. Clin. Med. 2020, 9, 1327. https://doi.org/10.3390/jcm9051327
Powierza K, Żelazowska-Rutkowska B, Sawicka-Powierza J, Mikołuć B, Urban B, Zaremba W, Cylwik B, Bakunowicz-Łazarczyk A. Endothelin-1 Serum Concentration is Lower in Children and Adolescents with High Myopia, a Preliminary Study. Journal of Clinical Medicine. 2020; 9(5):1327. https://doi.org/10.3390/jcm9051327
Chicago/Turabian StylePowierza, Katarzyna, Beata Żelazowska-Rutkowska, Jolanta Sawicka-Powierza, Bożena Mikołuć, Beata Urban, Wojciech Zaremba, Bogdan Cylwik, and Alina Bakunowicz-Łazarczyk. 2020. "Endothelin-1 Serum Concentration is Lower in Children and Adolescents with High Myopia, a Preliminary Study" Journal of Clinical Medicine 9, no. 5: 1327. https://doi.org/10.3390/jcm9051327