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Endoscopic Ultrasound-Guided Treatments for Non-Variceal Upper GI Bleeding: A Review of the Literature

Gastroenterology and Digestive Endoscopy Unit, AOU Città della Salute e della Scienza, University of Turin, 10126 Turin, Italy
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(3), 866;
Received: 10 February 2020 / Revised: 10 March 2020 / Accepted: 19 March 2020 / Published: 21 March 2020
(This article belongs to the Special Issue New Trends and Advances in Non-Variceal Gastrointestinal Bleeding)
Endoscopic injection of glues, clotting factors, or sclerosing agents is a well-known therapy for the treatment of non-variceal upper gastrointestinal bleeding (NVUGIB), but less is known about endoscopic ultrasound (EUS)-guided treatments. In this setting, literature data are scarce, and no randomized controlled trials are available. We performed a review of the existing literature in order to evaluate the role of EUS-guided therapies in the management of NVUGIB. The most common treated lesions were Dieulafoy’s lesions, pancreatic pseudoaneurysms, and gastrointestinal stromal tumors (GISTs). Mostly, the treatments were performed as a salvage option after failure of conventional endoscopic hemostatic attempts, showing good efficacy and a good safety profile, also documented by Doppler monitoring of treated lesions. EUS-guided therapies may be an effective option in the treatment of refractory NVUGIB, thus avoiding radiological or surgical management. Nevertheless, available literature still lacks robust data. View Full-Text
Keywords: EUS; bleeding; hemostasis; Dieulafoy; pseudoaneurysm; endotherapy EUS; bleeding; hemostasis; Dieulafoy; pseudoaneurysm; endotherapy
MDPI and ACS Style

De Angelis, C.G.; Cortegoso Valdivia, P.; Rizza, S.; Venezia, L.; Rizzi, F.; Gesualdo, M.; Saracco, G.M.; Pellicano, R. Endoscopic Ultrasound-Guided Treatments for Non-Variceal Upper GI Bleeding: A Review of the Literature. J. Clin. Med. 2020, 9, 866.

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