Next Article in Journal
Male Infertility: Shining a Light on Lipids and Lipid-Modulating Enzymes in the Male Germline
Next Article in Special Issue
Cardiac Autonomic Dysfunction in Multiple Sclerosis: A Systematic Review of Current Knowledge and Impact of Immunotherapies
Previous Article in Journal
Statin and Cancer Mortality and Survival: An Umbrella Systematic Review and Meta-Analysis
Previous Article in Special Issue
A Systematic Review and Meta-Analysis of Within-Person Changes in Cardiac Vagal Activity across the Menstrual Cycle: Implications for Female Health and Future Studies
Open AccessArticle

Impact of Using Different Levels of Threshold-Based Artefact Correction on the Quantification of Heart Rate Variability in Three Independent Human Cohorts

1
PROFITH “PROmoting FITness and Health Through Physical Activity” Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18011 Granada, Spain
2
EFFECTS-262 Research Group, Department of Physiology, School of Medicine, University of Granada, 18071 Granada, Spain
3
Department of Rehabilitation Sciences, KU Leuven, University of Leuven, 3000 Leuven, Belgium
4
Faculty of Physical Education and Physiotherapy, Opole University of Technology, 45-758 Opole, Poland
5
Department of Cardiology, University Hospital in Opole, University of Opole, 45-401 Opole, Poland
6
Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
7
Department of Medicine, division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333 Leiden, The Netherlands
*
Author to whom correspondence should be addressed.
These authors have made an equal contribution.
J. Clin. Med. 2020, 9(2), 325; https://doi.org/10.3390/jcm9020325
Received: 23 December 2019 / Revised: 20 January 2020 / Accepted: 21 January 2020 / Published: 23 January 2020
(This article belongs to the Special Issue Autonomic Nervous System: From Bench to Bedside)
Heart rate variability (HRV) is a non-invasive indicator of autonomic nervous system function. HRV recordings show artefacts due to technical and/or biological issues. The Kubios software is one of the most used software to process HRV recordings, offering different levels of threshold-based artefact correction (i.e., Kubios filters). The aim of the study was to analyze the impact of different Kubios filters on the quantification of HRV derived parameters from short-term recordings in three independent human cohorts. A total of 312 participants were included: 107 children with overweight/obesity (10.0 ± 1.1 years, 58% men), 132 young adults (22.2 ± 2.2 years, 33% men) and 73 middle-aged adults (53.6 ± 5.2 years, 48% men). HRV was assessed using a heart rate monitor during 10–15 min, and the Kubios software was used for HRV data processing using all the Kubios filters available (i.e., 6). Repeated-measures analysis of variance indicated significant differences in HRV derived parameters in the time-domain (all p < 0.001) across the Kubios filters in all cohorts, moreover similar results were observed in the frequency-domain. When comparing two extreme Kubios filters, these statistical differences could be clinically relevant, e.g. more than 10 ms in the standard deviation of all normal R-R intervals (SDNN). In conclusion, the results of the present study suggest that the application of different Kubios filters had a significant impact on HRV derived parameters obtained from short-term recordings in both time and frequency-domains. View Full-Text
Keywords: Kubios software; autonomic nervous system; data processing; children; young adults; middle-aged adults Kubios software; autonomic nervous system; data processing; children; young adults; middle-aged adults
Show Figures

Figure 1

MDPI and ACS Style

Alcantara, J.M.A.; Plaza-Florido, A.; Amaro-Gahete, F.J.; Acosta, F.M.; Migueles, J.H.; Molina-Garcia, P.; Sacha, J.; Sanchez-Delgado, G.; Martinez-Tellez, B. Impact of Using Different Levels of Threshold-Based Artefact Correction on the Quantification of Heart Rate Variability in Three Independent Human Cohorts. J. Clin. Med. 2020, 9, 325. https://doi.org/10.3390/jcm9020325

AMA Style

Alcantara JMA, Plaza-Florido A, Amaro-Gahete FJ, Acosta FM, Migueles JH, Molina-Garcia P, Sacha J, Sanchez-Delgado G, Martinez-Tellez B. Impact of Using Different Levels of Threshold-Based Artefact Correction on the Quantification of Heart Rate Variability in Three Independent Human Cohorts. Journal of Clinical Medicine. 2020; 9(2):325. https://doi.org/10.3390/jcm9020325

Chicago/Turabian Style

Alcantara, Juan M.A.; Plaza-Florido, Abel; Amaro-Gahete, Francisco J.; Acosta, Francisco M.; Migueles, Jairo H.; Molina-Garcia, Pablo; Sacha, Jerzy; Sanchez-Delgado, Guillermo; Martinez-Tellez, Borja. 2020. "Impact of Using Different Levels of Threshold-Based Artefact Correction on the Quantification of Heart Rate Variability in Three Independent Human Cohorts" J. Clin. Med. 9, no. 2: 325. https://doi.org/10.3390/jcm9020325

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop