Next Article in Journal
Effectiveness of Active Therapy-Based Training to Improve the Balance in Patients with Fibromyalgia: A Systematic Review with Meta-Analysis
Next Article in Special Issue
Silver Sulfadiazine Eradicates Antibiotic-Tolerant Staphylococcus aureus and Pseudomonas aeruginosa Biofilms in Patients with Infected Diabetic Foot Ulcers
Previous Article in Journal
Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer
Previous Article in Special Issue
Characteristics and Outcome for Persons with Diabetic Foot Ulcer and No-Option Critical Limb Ischemia
Open AccessArticle

Utility of Blood Parameters to Detect Complications during Long-Term Follow-Up in Patients with Diabetic Foot Osteomyelitis

Diabetic Foot Unit, Clínica Universitaria de Podología, Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(11), 3768; https://doi.org/10.3390/jcm9113768
Received: 23 October 2020 / Revised: 14 November 2020 / Accepted: 19 November 2020 / Published: 22 November 2020
(This article belongs to the Special Issue Diabetic Foot Complications: Current Challenges and Future Prospects)
The evidence is still unclear regarding the role of blood parameters in detecting complications in patients who suffer from diabetic foot osteomyelitis (DFO). In this study, the aim was to identify the capacity of different blood parameters in the diagnosis and prediction of the onset of complications. A cross-sectional prospective study was carried out with 116 DFO patients. The following blood parameters were evaluated during 1 year of follow-up: leukocytes, neutrophils, lymphocytes, monocytes, eosinophils, basophils, erythrocyte sedimentation rate (ESR), glycemia, glycosylated hemoglobin, C-reactive protein (CRP), alkaline phosphatase, albumin, and creatinine. Complication events were assessed for each participant during the study period. We investigated the association between blood parameter values and the onset of complication events by conducting a receiver operating characteristic curve analysis. Eighty-five (73.3%) patients developed complications. Regarding blood parameters, higher values of lymphocytes and albumin were predictive factors at the 12-month follow-up once the ulcer had healed. Higher values of ESR had predictive and diagnostic value for the onset of complication events, and higher values of CRP and hyperglycemia were diagnostic factors since they were elevated during the occurrence of an event. In conclusion, after suffering from DFO, the elevation of lymphocytes, ESR, CRP, albumin, and glycemia could be useful in detecting and diagnosing patients who are likely to develop a complication. Serial blood tests are a useful tool for early detection by healthcare professionals to prevent complications. View Full-Text
Keywords: blood parameters; diabetic foot osteomyelitis (DFO); long-term complications blood parameters; diabetic foot osteomyelitis (DFO); long-term complications
Show Figures

Figure 1

MDPI and ACS Style

Tardáguila-García, A.; García Álvarez, Y.; García-Morales, E.; Álvaro-Afonso, F.J.; Sanz-Corbalán, I.; Lázaro-Martínez, J.L. Utility of Blood Parameters to Detect Complications during Long-Term Follow-Up in Patients with Diabetic Foot Osteomyelitis. J. Clin. Med. 2020, 9, 3768.

AMA Style

Tardáguila-García A, García Álvarez Y, García-Morales E, Álvaro-Afonso FJ, Sanz-Corbalán I, Lázaro-Martínez JL. Utility of Blood Parameters to Detect Complications during Long-Term Follow-Up in Patients with Diabetic Foot Osteomyelitis. Journal of Clinical Medicine. 2020; 9(11):3768.

Chicago/Turabian Style

Tardáguila-García, Aroa; García Álvarez, Yolanda; García-Morales, Esther; Álvaro-Afonso, Francisco J.; Sanz-Corbalán, Irene; Lázaro-Martínez, José L. 2020. "Utility of Blood Parameters to Detect Complications during Long-Term Follow-Up in Patients with Diabetic Foot Osteomyelitis" J. Clin. Med. 9, no. 11: 3768.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop