Association between Obstructive Sleep Apnea and SYNTAX Score
1
Department of Cardiovascular Medicine, Juntendo University School of Medicine, Tokyo 113-8421, Japan
2
Cardiovascular Respiratory Sleep Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan
3
Department of Cardiovascular Medicine, Toranomon Hospital, Tokyo 105-8470, Japan
4
Department of Sleep Medicine, Toranomon Hospital, Tokyo 105-8470, Japan
5
Sleep and Sleep-Disordered Breathing Center, Juntendo University Hospital, Tokyo 113-8421, Japan
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(10), 3314; https://doi.org/10.3390/jcm9103314
Received: 20 September 2020
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Revised: 14 October 2020
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Accepted: 14 October 2020
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Published: 15 October 2020
(This article belongs to the Special Issue Sleep-Disordered Breathing in Cardiovascular Disease)
Obstructive sleep apnea (OSA) is related to an increased risk of cardiovascular diseases, including coronary artery disease (CAD). We investigated the association between OSA and the severity of CAD by assessing coronary angiography findings. We retrospectively analyzed patients who underwent their first coronary angiography to evaluate CAD and polysomnography (PSG) to investigate the severity of OSA in our hospital from March 2002 to May 2015. The severity of CAD was determined based on coronary angiography findings using the SYNTAX score. The patients were divided into two groups according to the apnea-hypopnea index (AHI): mild OSA (AHI < 15/h) and moderate-to-severe OSA (AHI ≥ 15/h). Overall, 98 patients were enrolled. The SYNTAX score was significantly different between the two groups (p = 0.001). After adjustment for other risk factors, including age, sex, obesity, hypertension, hyperlipidemia, diabetes mellitus, smoking status, and family history of CAD, moderate-to-severe OSA significantly correlated to the SYNTAX score (partial correlations = 0.24, p = 0.039). These results suggest that the severity of CAD is related to moderate-to-severe OSA.
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Keywords:
coronary artery disease; obstructive sleep apnea; severity
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MDPI and ACS Style
Ishiwata, S.; Tomita, Y.; Ishiwata, S.; Narui, K.; Daida, H.; Kasai, T. Association between Obstructive Sleep Apnea and SYNTAX Score. J. Clin. Med. 2020, 9, 3314. https://doi.org/10.3390/jcm9103314
AMA Style
Ishiwata S, Tomita Y, Ishiwata S, Narui K, Daida H, Kasai T. Association between Obstructive Sleep Apnea and SYNTAX Score. Journal of Clinical Medicine. 2020; 9(10):3314. https://doi.org/10.3390/jcm9103314
Chicago/Turabian StyleIshiwata, Sayaki, Yasuhiro Tomita, Sugao Ishiwata, Koji Narui, Hiroyuki Daida, and Takatoshi Kasai. 2020. "Association between Obstructive Sleep Apnea and SYNTAX Score" Journal of Clinical Medicine 9, no. 10: 3314. https://doi.org/10.3390/jcm9103314
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