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Use of DIAGNOdent and VistaProof in diagnostic of Pre-Cavitated Caries Lesions—A Systematic Review and Meta-Analysis

Stomatology Department, University of Valencia, 46010 Valencia, Spain
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J. Clin. Med. 2020, 9(1), 20; https://doi.org/10.3390/jcm9010020
Received: 22 November 2019 / Revised: 13 December 2019 / Accepted: 17 December 2019 / Published: 19 December 2019
(This article belongs to the Section Stomatology)
Objective: To analyse the published evidence of the validity of DIAGNDOdent and VistaProof in diagnosing carious depths in pre-cavitated lesions. Material and methods: A systematic review was carried out after identifying a total of 184 articles, including 27 concerning the qualitative review and a subsequent meta-analysis. The quality of the studies was evaluated by using the QUADAS-2 tool. Results: For DIAGNOdent, the sensitivity value was 0.77, the specificity value was 0.75 and AUC was 0.81 for the global meta-analyses. In relation to subgroups, the values estimated 0.85, 0.76 and 0.86, respectively, for the in vivo group and 0.71, 0.75 and 0.83 for the in vitro group. For VistaProof, sensitivity was 0.81, specificity 0.75 and AUC had a value of 0.80 in the global meta-analysis. For the subgroups, these were considered at 0.75, 0.81 and 0.89, respectively, for the in vivo group and 0.91, 0.74 and 0.76 for the in vitro group. Neither case presented publication bias when analysing the funnel plot, the classic fail-safe number and Egger’s intercept. Conclusion: Both VistaProof and DIAGNOdent are valid as they offer a moderate to high diagnostic effectiveness for dentine depth in pre-cavitated lesions. View Full-Text
Keywords: caries diagnosis; laser fluorescence; incipient caries; DIAGNOdent; VistaProof caries diagnosis; laser fluorescence; incipient caries; DIAGNOdent; VistaProof
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Iranzo-Cortés, J.E.; Montiel-Company, J.M.; Almerich-Torres, T.; Bellot-Arcís, C.; Almerich-Silla, J.M. Use of DIAGNOdent and VistaProof in diagnostic of Pre-Cavitated Caries Lesions—A Systematic Review and Meta-Analysis. J. Clin. Med. 2020, 9, 20.

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