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Emerging and Novel Treatments for Pituitary Tumors
Open AccessReview

Hypothalamic Endocrine Tumors: An Update

by Sylvia L. Asa 1,2,* and Ozgur Mete 2,3
1
Department of Pathology, Case Western University and University Hospitals, Cleveland, OH 44106, USA
2
Department of Pathology, University Health Network, Toronto, ON M5G 2C4, Canada
3
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 1L7, Canada
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2019, 8(10), 1741; https://doi.org/10.3390/jcm8101741
Received: 25 September 2019 / Revised: 5 October 2019 / Accepted: 10 October 2019 / Published: 20 October 2019
(This article belongs to the Special Issue Advances in the Diagnosis and Therapy of Pituitary Disorders)
The hypothalamus is the site of synthesis and secretion of a number of endocrine peptides that are involved in the regulation of hormonal activity of the pituitary and other endocrine targets. Tumors of the hypothalamus have been recognized to have both structural and functional effects including hormone hypersecretion. The classification of these tumors has advanced over the last few years, and biomarkers are now available to classify these tumors and provide accurate structure–function correlations. This review provides an overview of tumors in this region that is critical to metabolic homeostasis with a focus on advances in the diagnosis of gangliocytomas, neurocytomas, and pituicytomas that are unique to this region. View Full-Text
Keywords: hypothalamus; endocrine; gangliocytoma; neurocytoma; pituicytoma; hormones hypothalamus; endocrine; gangliocytoma; neurocytoma; pituicytoma; hormones
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Asa, S.L.; Mete, O. Hypothalamic Endocrine Tumors: An Update. J. Clin. Med. 2019, 8, 1741.

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