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Neuroendocrine Disturbances after Brain Damage: An Important and Often Undiagnosed Disorder
Open AccessArticle

Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism

1
Division of Endocrinology and Diabetes, RWTH Aachen University, 52062 Aachen, Germany
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Department of Neuroradiology, RWTH Aachen University, 52062 Aachen, Germany
3
Department of Neurosurgery, University Hospital Essen, 45147 Essen, Germany
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Author to whom correspondence should be addressed.
Academic Editors: Günter Stalla and Anna Kopczak
J. Clin. Med. 2015, 4(5), 965-969; https://doi.org/10.3390/jcm4050965
Received: 27 March 2015 / Revised: 30 April 2015 / Accepted: 6 May 2015 / Published: 15 May 2015
(This article belongs to the Special Issue Neuroendocrine Disturbances after Brain Damage)
We report a case of a previously undiagnosed panhypopituitarism initially presenting as a full-blown Addisonian crisis with hypoglycemia, hyponatremia, hypotension and neuropsychological symptoms, more than 30 years after a severe traumatic brain injury (TBI). The patient also displayed clearly visible pathognomonic clinical signs of long-standing pituitary dysfunction. The case highlights the importance of being aware of endocrine sequelae even decades after serious TBI. View Full-Text
Keywords: traumatic brain injury; hypopituitarism; neuroendocrine dysfunction; hypocortisolism; Addisonian crisis traumatic brain injury; hypopituitarism; neuroendocrine dysfunction; hypocortisolism; Addisonian crisis
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Streetz-van der Werf, C.; Karges, W.; Blaum, M.; Kreitschmann-Andermahr, I. Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism. J. Clin. Med. 2015, 4, 965-969.

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