Robotic Gastrointestinal Surgery Compared to Conventional Approaches: An Umbrella Review of Clinical and Economic Outcomes
Abstract
1. Introduction
2. Materials and Methods
2.1. Search Strategy
2.2. Eligibility Criteria
2.3. Screening and Data Extraction
2.4. Methodological Quality Assessment
3. Results
3.1. Study Selection
3.2. Methodological Quality Assessment
3.3. Esophageal Surgery
3.3.1. Technical Considerations
3.3.2. Advantages and Limitations
3.3.3. Cost-Effectiveness
3.4. Gastric Surgery
3.4.1. Technical Considerations
3.4.2. Advantages and Limitations
3.4.3. Cost-Effectiveness
3.5. Liver Surgery
3.5.1. Technical Considerations
3.5.2. Advantages and Limitations
3.5.3. Cost-Effectiveness
3.6. Biliary Surgery
3.6.1. Technical Considerations
3.6.2. Advantages and Limitations
3.6.3. Cost-Effectiveness
3.7. Pancreatic Surgery
3.7.1. Technical Considerations
3.7.2. Advantages and Limitations
3.7.3. Cost-Effectiveness
3.8. Colorectal Surgery
3.8.1. Technical Considerations
3.8.2. Advantages and Limitations
3.8.3. Cost-Effectiveness
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| AMSTAR2 | A Measurement Tool to Assess Systematic Reviews 2 |
| BMI | Body Mass Index |
| CCA | Corrected Covered Area |
| CUSA | Cavitron Ultrasonic Surgical Aspirator |
| DP | Distal Pancreatectomy |
| GI | Gastrointestinal |
| IPAA | Ileal Pouch-Anal Anastomosis |
| LG | Laparoscopic Gastrectomy |
| MIS | Minimally Invasive Surgery |
| PD | Pancreaticoduodenectomy |
| RAMIE | Robotic-Assisted Minimally Invasive Esophagectomy |
| RAS | Robotic-Assisted Surgery |
| RG | Robotic Gastrectomy |
| RLR | Robotic Liver Resection |
| SP | Single-Port |
| TME | Total Mesorectal Excision |
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| Domain | Number of Reviews | AMSTAR 2 Evaluation | CCA Value (%) | Overlap Level |
|---|---|---|---|---|
| Esophageal | 25 | High: 10, Moderate: 0, Low: 4, Critically low: 11 | 8.97% | Moderate |
| Gastric | 44 | High: 0, Moderate: 30, Low: 10, Critically low: 4 | 6.81% | Moderate |
| Liver | 33 | High: 16, Moderate: 11, Low: 1, Critically low: 5 | 8.93% | Moderate |
| Biliary | 30 | High: 5, Moderate: 0, Low: 9, Critically low: 16 | 0.61% | Slight |
| Pancreatic | 40 | High: 15, Moderate: 2, Low: 14, Critically low: 9 | 0.02% | Slight |
| Colorectal | 78 | High: 27, Moderate: 22, Low: 19, Critically low: 10 | 0.01% | Slight |
| Domain | Optimal Indications | Established Clinical Benefits | Cost-Effectiveness | Evidence-Based Conclusion |
|---|---|---|---|---|
| Esophageal | McKeown or Ivor Lewis esophagectomy; Heller myotomy | Lower pulmonary and nerve injury rates; Improved lymph node yield | Potentially justified in complex cases | Selectively recommended for complex cases. |
| Gastric | D2 lymphadenectomy; High-risk or obese patients | Lower conversion and complication rates; Improved lymphadenectomy and anastomotic precision | Moderate only in high-risk cases | Selectively recommended for high-risk cases; cost restricts broad adoption. |
| Liver | Posterior segmentectomy; Bile duct reconstruction; Cirrhotic liver | Lower conversion rates; Shorter hospital stays; Enhanced access in complex resections | Favorable only in complex resections | Selectively recommended for complex cases; cost and debated clinical superiority restrict routine use. |
| Biliary | Hilar cholangiocarcinoma; Hepaticojejunostomy; High BMI or inflammation | Enhanced dissection and suturing in confined spaces; Improved lymphadenectomy and anastomotic precision; Comparable in benign disease | Potentially justified in complex or high-risk oncologic cases | Selectively recommended for high-risk cases; further evidence needed to justify broader adoption. |
| Pancreatic | PD; Spleen-preserving DP; High-risk or obese patients | Lower conversion rates; Improved anastomotic precision in PD; Comparable oncologic outcomes | Favorable in complex cases and high-volume centers; Improves with training and experience | Strongest evidence of clinical value in high-risk cases or advanced centers; not yet scalable for routine implementation. |
| Colorectal | TME; IPAA; Rectal cancer in male or obese patients | Lower complication and conversion rates; Shorter hospital stays; Improved nerve preservation | Reasonable in complex cases; Justified by reduced morbidity and enhanced functional outcomes | Substantial advantages in high-risk pelvic cases, particularly rectal cancer; cost restricts routine use for benign conditions. |
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© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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Rho, S.H.; Lee, J.; Lee, J.S. Robotic Gastrointestinal Surgery Compared to Conventional Approaches: An Umbrella Review of Clinical and Economic Outcomes. J. Clin. Med. 2025, 14, 8555. https://doi.org/10.3390/jcm14238555
Rho SH, Lee J, Lee JS. Robotic Gastrointestinal Surgery Compared to Conventional Approaches: An Umbrella Review of Clinical and Economic Outcomes. Journal of Clinical Medicine. 2025; 14(23):8555. https://doi.org/10.3390/jcm14238555
Chicago/Turabian StyleRho, Seung Hyun, Jeonghyun Lee, and Jun Suh Lee. 2025. "Robotic Gastrointestinal Surgery Compared to Conventional Approaches: An Umbrella Review of Clinical and Economic Outcomes" Journal of Clinical Medicine 14, no. 23: 8555. https://doi.org/10.3390/jcm14238555
APA StyleRho, S. H., Lee, J., & Lee, J. S. (2025). Robotic Gastrointestinal Surgery Compared to Conventional Approaches: An Umbrella Review of Clinical and Economic Outcomes. Journal of Clinical Medicine, 14(23), 8555. https://doi.org/10.3390/jcm14238555

