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Volume 14
Issue 20
10.3390/jcm14207251
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This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Review

Mitral Valve Repair in the Modern Era: Insights into Techniques and Technologies with a Glimpse of the Future

by
Marco Rolando
1,*,
Alessandro Affronti
2,
Francesco Loreni
2,
Marcello Bergonzini
2,
Erberto Carluccio
3,† and
Federico Fortuni
3,†
1
Independent Cardiologist Researcher, 63100 Ascoli Piceno, Italy
2
Cardiac Surgery Unit, Santa Maria Della Misericordia Hospital, 06129 Perugia, Italy
3
Cardiology and Cardiovascular Pathophysiology, Santa Maria Della Misericordia Hospital, University of Perugia, 06129 Perugia, Italy
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
J. Clin. Med. 2025, 14(20), 7251; https://doi.org/10.3390/jcm14207251 (registering DOI)
Submission received: 4 September 2025 / Revised: 3 October 2025 / Accepted: 10 October 2025 / Published: 14 October 2025
(This article belongs to the Special Issue Mitral Valve Surgery: Current Status and Future Challenges)
Versions Notes

Abstract

Mitral valve repair has evolved significantly with the advent of advanced surgical and transcatheter techniques. Innovations such as 3D visualization, robotic surgery, and transcatheter edge-to-edge repair have improved procedural precision and expanded treatment options for high-risk patients. Emerging technologies, including transcatheter mitral valve repair, annuloplasty, and chordal systems, offer tailored solutions for complex mitral pathology. Personalized treatment strategies, guided by multimodality imaging and artificially intelligence-driven planning, are reshaping clinical decision-making. Ongoing trials and next-generation devices are poised to enhance long-term outcomes, marking a shift toward minimally invasive, precision-guided mitral valve therapy. This review aims to provide a comprehensive overview of recent technological advances, clinical applications, and future directions in mitral valve repair across surgical and interventional domains.
Keywords: mitral valve repair; minimally invasive cardiac surgery; robotic surgery; mitral regurgitation; transcatheter mitral valve intervention mitral valve repair; minimally invasive cardiac surgery; robotic surgery; mitral regurgitation; transcatheter mitral valve intervention

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MDPI and ACS Style

Rolando, M.; Affronti, A.; Loreni, F.; Bergonzini, M.; Carluccio, E.; Fortuni, F. Mitral Valve Repair in the Modern Era: Insights into Techniques and Technologies with a Glimpse of the Future. J. Clin. Med. 2025, 14, 7251. https://doi.org/10.3390/jcm14207251

AMA Style

Rolando M, Affronti A, Loreni F, Bergonzini M, Carluccio E, Fortuni F. Mitral Valve Repair in the Modern Era: Insights into Techniques and Technologies with a Glimpse of the Future. Journal of Clinical Medicine. 2025; 14(20):7251. https://doi.org/10.3390/jcm14207251

Chicago/Turabian Style

Rolando, Marco, Alessandro Affronti, Francesco Loreni, Marcello Bergonzini, Erberto Carluccio, and Federico Fortuni. 2025. "Mitral Valve Repair in the Modern Era: Insights into Techniques and Technologies with a Glimpse of the Future" Journal of Clinical Medicine 14, no. 20: 7251. https://doi.org/10.3390/jcm14207251

APA Style

Rolando, M., Affronti, A., Loreni, F., Bergonzini, M., Carluccio, E., & Fortuni, F. (2025). Mitral Valve Repair in the Modern Era: Insights into Techniques and Technologies with a Glimpse of the Future. Journal of Clinical Medicine, 14(20), 7251. https://doi.org/10.3390/jcm14207251

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