Peer-Review Record
Impact of Corneal Crosslinking on Endothelial and Biomechanical Parameters in Keratoconus
J. Clin. Med. 2025, 14(13), 4489; https://doi.org/10.3390/jcm14134489
by
Maria-Silvia Dina 1,*, Maria-Cristina Marinescu 1
, Cătălina-Gabriela Corbu 2, Mihaela-Monica Constantin 2, Cătălina-Ioana Tătaru 3 and Călin-Petru Tătaru 3
, Cătălina-Gabriela Corbu 2, Mihaela-Monica Constantin 2, Cătălina-Ioana Tătaru 3 and Călin-Petru Tătaru 3Reviewer 1:
Reviewer 2:
J. Clin. Med. 2025, 14(13), 4489; https://doi.org/10.3390/jcm14134489
Submission received: 2 May 2025
/
Revised: 26 May 2025
/
Accepted: 21 June 2025
/
Published: 25 June 2025
(This article belongs to the Section Ophthalmology)
Round 1
Reviewer 1 Report
Comments and Suggestions for Authors
- Were the patients on any medications between 2019 and 2022 to maintain endothelial cell density?
- What are the primary causes of endothelial cell density reduction at each stage of keratoconus, and how can endothelial cell density be preserved throughout the progression of the disease?
Author Response
Please see the attachment.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Comments and Suggestions for Authors
Questions:
1. The study was designed as a non-randomised study. Please discuss its limitations in the discussion section so that someone can try a randomised study in the future.
2. In the biomechanical property, Intracocular pressure (IOP) was not discussed with the different Keratoconus of T0, T1 and T6?
Author Response
Please see the attachment.
Author Response File: Author Response.pdf
