Embolization of De Novo Pulmonary Arteriovenous Malformations Using High-Volume Detachable Non-Fibered Coils: Propensity-Matched Comparison to Traditional Coils

Mathevosian, Sipan; Sparks, Hiro D.; Cusumano, Lucas R.; Roberts, Dustin G.; Majumdar, Shamaita; McWilliams, Justin P.

doi:10.3390/jcm13030648

Open AccessArticle

Embolization of De Novo Pulmonary Arteriovenous Malformations Using High-Volume Detachable Non-Fibered Coils: Propensity-Matched Comparison to Traditional Coils

by

Sipan Mathevosian

,

Hiro D. Sparks

,

Lucas R. Cusumano

,

Dustin G. Roberts

,

Shamaita Majumdar

and

Justin P. McWilliams

^*

Division of Interventional Radiology, Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA

^*

Author to whom correspondence should be addressed.

J. Clin. Med. 2024, 13(3), 648; https://doi.org/10.3390/jcm13030648

Submission received: 29 November 2023 / Revised: 4 January 2024 / Accepted: 8 January 2024 / Published: 23 January 2024

(This article belongs to the Special Issue Hereditary Hemorrhagic Telangiectasia: Recent Advances and Future Challenges—2nd Edition)

Download

Browse Figures

Versions Notes

Abstract

Embolization of de novo pulmonary arteriovenous malformations (PAVMs) using high-volume detachable non-fibered (HVDNF) coils was compared to traditional non-HVDNF coils. Persistent-occlusion rates were evaluated. A total of 272 de novo (previously untreated) PAVM treatments were retrospectively stratified into those treated with non-HVDNF coils only (n = 192) and those treated with HVDNF coils with or without other coils (n = 80). Propensity score matching, followed by survival analysis and cost analysis, was performed. The overall persistent-occlusion rate was 86.0% (234/272). Persistent occlusion was achieved in 81.8% of PAVMs using non-HVDNF coils, compared with 96.3% using HVDNF coils (p = 0.0017). The mean follow-up was 30.7 ± 31.9 months versus 14.7 ± 13.4 months, respectively (p < 0.0001). Propensity-matched survival analysis demonstrated PAVMs treated with HVDNF coils recurred significantly less frequently than PAVMs treated with non-HVNDF coils (p = 0.023). The use of HVDNF coils was more expensive than standard coils, however not significantly different for the treatment of complex PAVMs. The use of high-volume detachable non-fibered coils was associated with higher persistent-occlusion rates when compared with non-HVDNF coils. HVDNF coils were more expensive on average; however, cost was similar between groups for the treatment of complex PAVMs.

Keywords: Pulmonary Arteriovenous Malformation (PAVM); embolization; Hereditary Hemorrhagic Telangiectasia (HHT); vascular medicine; pulmonary angiography; pulmonary embolization

Share and Cite

MDPI and ACS Style

Mathevosian, S.; Sparks, H.D.; Cusumano, L.R.; Roberts, D.G.; Majumdar, S.; McWilliams, J.P. Embolization of De Novo Pulmonary Arteriovenous Malformations Using High-Volume Detachable Non-Fibered Coils: Propensity-Matched Comparison to Traditional Coils. J. Clin. Med. 2024, 13, 648. https://doi.org/10.3390/jcm13030648

AMA Style

Mathevosian S, Sparks HD, Cusumano LR, Roberts DG, Majumdar S, McWilliams JP. Embolization of De Novo Pulmonary Arteriovenous Malformations Using High-Volume Detachable Non-Fibered Coils: Propensity-Matched Comparison to Traditional Coils. Journal of Clinical Medicine. 2024; 13(3):648. https://doi.org/10.3390/jcm13030648

Chicago/Turabian Style

Mathevosian, Sipan, Hiro D. Sparks, Lucas R. Cusumano, Dustin G. Roberts, Shamaita Majumdar, and Justin P. McWilliams. 2024. "Embolization of De Novo Pulmonary Arteriovenous Malformations Using High-Volume Detachable Non-Fibered Coils: Propensity-Matched Comparison to Traditional Coils" Journal of Clinical Medicine 13, no. 3: 648. https://doi.org/10.3390/jcm13030648

APA Style

Mathevosian, S., Sparks, H. D., Cusumano, L. R., Roberts, D. G., Majumdar, S., & McWilliams, J. P. (2024). Embolization of De Novo Pulmonary Arteriovenous Malformations Using High-Volume Detachable Non-Fibered Coils: Propensity-Matched Comparison to Traditional Coils. Journal of Clinical Medicine, 13(3), 648. https://doi.org/10.3390/jcm13030648

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Menu

Embolization of De Novo Pulmonary Arteriovenous Malformations Using High-Volume Detachable Non-Fibered Coils: Propensity-Matched Comparison to Traditional Coils

Abstract

Share and Cite

Article Metrics

Article Access Statistics

Further Information

Guidelines

MDPI Initiatives

Follow MDPI