One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study

Carratù, Pierluigi; Dragonieri, Silvano; Quaranta, Vitaliano Nicola; Resta, Onofrio; Portincasa, Piero; Palmieri, Vincenzo Ostilio; Carpagnano, Giovanna Elisiana

doi:10.3390/jcm13216360

Open AccessArticle

One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study

by

Pierluigi Carratù

^1,*

,

Silvano Dragonieri

²

,

Vitaliano Nicola Quaranta

²

,

Onofrio Resta

²,

Piero Portincasa

¹

,

Vincenzo Ostilio Palmieri

¹ and

Giovanna Elisiana Carpagnano

²

¹

Institute of Internal Medicine “A. Murri”, Department DIMEPRE-J, University of Medicine, 70124 Bari, Italy

²

Institute of Respiratory Diseases, Department DIBRAIN, University of Medicine, 70124 Bari, Italy

^*

Author to whom correspondence should be addressed.

J. Clin. Med. 2024, 13(21), 6360; https://doi.org/10.3390/jcm13216360

Submission received: 24 September 2024 / Revised: 15 October 2024 / Accepted: 21 October 2024 / Published: 24 October 2024

(This article belongs to the Special Issue Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS))

Download

Browse Figure

Versions Notes

Abstract

Background/Objectives: This study evaluated the impact of continuous positive airway pressure (C-PAP) therapy combined with a rigorous diet regimen on obese patients with obstructive sleep apnea syndrome (OSAS). Methods: Sixty obese patients (BMI ≥ 30) diagnosed with severe OSAS were recruited in order to establish the evaluation of CPAP therapy with different extents of adherence to a rigorous diet regimen. After one year, significant improvements were observed. Results: BMI reduced by 12.32%, apnea–hypopnea index (AHI) by 22.04%, oxygen desaturation index (ODI) by 15.87%, total sleep time with oxygen saturation below 90% (TST90%) by 25.2%, and Epworth Sleepiness Scale (ESS) scores by 21.74%. Patients were, then, divided into three groups, based on adherence to the restricted diet, as well as to the correct use of the nocturnal C-PAP, showing different reductions in BMI, AHI, ODI, TST90%, and ESS, according to their adherence, based on the sum of % reduction in BMI + AHI into three groups. Conclusions: These findings underscore the effectiveness of combining C-PAP therapy with a strict diet in improving OSAS symptoms and overall health in obese patients. Future studies with larger cohorts and longer follow-up periods are needed to confirm these results and explore the long-term benefits of this integrated approach.

Keywords: obesity; OSAS; C-PAP; diet; BMI; AHI

Share and Cite

MDPI and ACS Style

Carratù, P.; Dragonieri, S.; Quaranta, V.N.; Resta, O.; Portincasa, P.; Palmieri, V.O.; Carpagnano, G.E. One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study. J. Clin. Med. 2024, 13, 6360. https://doi.org/10.3390/jcm13216360

AMA Style

Carratù P, Dragonieri S, Quaranta VN, Resta O, Portincasa P, Palmieri VO, Carpagnano GE. One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study. Journal of Clinical Medicine. 2024; 13(21):6360. https://doi.org/10.3390/jcm13216360

Chicago/Turabian Style

Carratù, Pierluigi, Silvano Dragonieri, Vitaliano Nicola Quaranta, Onofrio Resta, Piero Portincasa, Vincenzo Ostilio Palmieri, and Giovanna Elisiana Carpagnano. 2024. "One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study" Journal of Clinical Medicine 13, no. 21: 6360. https://doi.org/10.3390/jcm13216360

APA Style

Carratù, P., Dragonieri, S., Quaranta, V. N., Resta, O., Portincasa, P., Palmieri, V. O., & Carpagnano, G. E. (2024). One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study. Journal of Clinical Medicine, 13(21), 6360. https://doi.org/10.3390/jcm13216360

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Menu

One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study

Abstract

Share and Cite

Article Metrics

Article Access Statistics

Further Information

Guidelines

MDPI Initiatives

Follow MDPI