Pyoderma Gangrenosum, a Challenging Postpartum Diagnosis—Case Report and Literature Review
Abstract
:1. Introduction
2. Case Report
2.1. Patient History and Physical Examination
2.2. Histopathology Findings
2.3. Dermatological Management
3. Literature Search—Methodology and Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Report (Author and Year of Publications) | Onset of the Disease | Site of the Lesion | Age (Years) | Recurrence | Associated Pathology | Treatment |
---|---|---|---|---|---|---|
Harlaand et al. (1993) [20] | Postpartum (29 weeks) | C-section | 36 | No | No | corticotherapy |
Stone et al. (1996) [21] | Postpartum (29 weeks) | C-section | 36 | No | No | corticotherapy surgery |
Steadman et al. (1998) [22] | Postpartum (37 weeks) | C-section | 32 | No | No | corticotherapy |
Futami et al. (1998) [23] | Postpartum (vaginal birth) | Face, neck, upper arm, and thigh | 32 | Relapse | Ulcerative colitis | corticotherapy cyclosporine |
Ronnau et al. (2000) [24] | Postpartum (not specified) | C-section | 24 | Yes (third episode) | Chronic type C hepatitis | corticotherapy cyclosporine |
Skinner et al. (2006) [25] | Postpartum (39 weeks) | C-section | 36 | Yes After the vaginal delivery that occurred a year ago, she experienced a delayed healing perineal ulcer. | No | corticotherapy cyclosporine |
Karim et al. (2006) [26] | Postpartum (37 weeks) | C-section | 29 | No | No | corticotherapy cyclosporine |
Banga et al. (2007) [10] | Postpartum (29 weeks) | C-section | 32 | No | No | corticotherapy tacrolimus cream |
Aoussar et al. (2007) [27] | During pregnancy (16 weeks) Postpartum (not specified) | On the torso and on the limbs | 26 | Yes After one year during pregnancy (30 weeks of gestation) and after two years in postpartum (on the right arm—intramuscular injection site). | Takayasu arteritis, type B hepatitis | corticotherapy |
Sanz-Munoz et al. (2008) [5] | During pregnancy postpartum (not specified) | Anterior side of the left leg 4 days earlier C-section | 30 | No | No | corticotherapy |
Wiersma et al. (2009) [28] | Postpartum (not specified) | C-section | 31 | No | No | corticotherapy |
Pauser et al. (2009) [29] | Postpartum (not specified) | C-section | 39 | No | No | corticotherapy cyclosporine dapsone |
Wierzbicka-Hainaut et al. (2010) [30] | During pregnancy (third trimester) Postpartum (37 weeks) | Left calf C-section | 25 | Yes During her first and second pregnancy. | No | corticotherapy |
Kikuchi et al. (2010) [31] | Postpartum (not specified) | C-section | 28 | No | No | corticotherapy |
Muresan et al. (2010) [32] | Postpartum (term) | C-section | 27 | Yes | No | corticotherapy |
Amin et al. (2014) [33] | Postpartum (32 weeks) | C-section | 32 | Yes Third recurrence, after every one of the three C-sections. | No | corticotherapy dapsone |
Aydin et al. (2015) [15] | Postpartum (37 weeks) | C-section | 32 | Yes Previous C-section and left hand at the site of intravenous catheterization. | No | corticotherapy azathioprine—unresponsive vacuum-assisted closure split-thickness skin graft |
Radhika et al. (2015) [34] | Postpartum (term) | C-section | 22 | Yes After an intramuscular injection on her buttock. | No | corticotherapy cyclosporin dapsone |
Simmons et al. (2015) [35] | Postpartum (27 weeks) | C-section | 43 | No | No | corticotherapy |
Cokan et al. (2016) [36] | Postpartum (not specified abruptio placentae) | C-section Left breast | 23 | No | No | corticotherapy |
Park et al. (2016) [14] | Postpartum (term) | C-section | 33 | No | No (antiphospholipid antigen—weakly positive) | corticotherapy cyclosporine |
Nonaka et al. (2016) [37] | Postpartum (36 weeks) | C-section | 39 | No | Antiphospholipid syndrome (lupus anticoagulant weakly positive but with 3 spontaneous abortions) | corticotherapy minocycline hydrochloride |
Alani et al. (2016) [38] | Postpartum (not specified) | Episiotomy | 29 | No | Hepatitis C | Corticotherapy cyclosporine mycophenolate mofetil dapsone |
Hilton et al. (2017) [39] | Postpartum (not specified) | C-section | 28 | No | No | corticotherapy dapsone |
Satoh et al. (2018) [40] | Postpartum (33 weeks) | C-section | 27 | Yes First episode after appendectomy 10 years previously. | No | corticotherapy |
Diallo et al. (2017) [18] | Postpartum (not specified) | C-section | 25 | No | No | corticotherapy |
Naciri et al. (2018) [41] | Postpartum (term) | C-section | 23 | Yes Abscess on her left breast prior to pregnancy | Peripartum/Postpartum cardiomyopathy | corticotherapy |
Murata et al. (2019) [42] | Postpartum (37 weeks) | C-section | 29 | Yes | No | corticotherapy |
Postpartum (33 weeks) | C-section | 27 | Yes | No | corticotherapy | |
Foessleitner et al. (2019) [43] | Postpartum (30 weeks) | C-section | 34 | No | No | negative pressure wound therapy high-dose corticosteroids therapy |
Shen et al. (2019) [4] | Postpartum (>7 months of gestation) | C-section | 32 | No | No | corticotherapy human immunoglobulin wound debridement vacuum sealing negative pressure drainage skin grafting hyperbaric oxygen therapy |
van Donkelaar et al. (2020) [44] | Postpartum (32 weeks) | C-section | 21 | No | No | corticotherapy |
Gunduz et al. (2020) [45] | Postpartum (not specified) | C-section Bilateral gluteal regions post NSAIDs administration | 32 | No | No | intravenous immunoglobulin |
Zolper et al. (2021) [46] | Postpartum (not specified) | C-section | 28 | Yes First episode (post-vaginal delivery) | No | corticotherapy cyclosporine incisional negative pressure wound therapy |
Moutos et al. (2021) [47] | Postpartum (28 weeks) | C-section | 23 | No | No | corticotherapy cyclosporine |
Ghumra et al. (2021) [48] | Postpartum (31 weeks) | C-section | 35 | Yes 14 years prior, skin grafts for ulcers on her left lower leg | No | corticotherapy cyclosporine |
Luo et al. (2021) [49] | Postpartum (not specified) | C-section | 38 | No | Hepatitis B | corticotherapy intravenous immunoglobulin |
Rao et al. (2021) [6] | Postpartum (not specified) | Episiotomy | 28 | No | No | corticotherapy |
Aziret et al. (2021) [50] | Postpartum (term) | C-section | 36 | No | No | corticotherapy |
Ishizaki et al. (2022) [51] | Postpartum (36 weeks) | C-section | 34 | No | Thrombocytopenia early in pregnancy | corticotherapy |
Bal et al. (2022) [52] | Postpartum (not specified abruptio placentae) | C-section | 25 | Yes 2 years prior—injection abscess right gluteal region healed with a large scar | No | corticotherapy |
Lyons et al. (2023) [53] | Postpartum | Right breast | 32 | No | No | corticotherapy cyclosporine skin graft |
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Matasariu, D.R.; Bujor, I.E.; Mihălceanu, E.; Gîscă, T.C.; Stâncanu, A.; Andriescu, E.C.; Popescu, I.; Socolov, D.; Vasiluță, C.; Ursache, A. Pyoderma Gangrenosum, a Challenging Postpartum Diagnosis—Case Report and Literature Review. J. Clin. Med. 2024, 13, 3653. https://doi.org/10.3390/jcm13133653
Matasariu DR, Bujor IE, Mihălceanu E, Gîscă TC, Stâncanu A, Andriescu EC, Popescu I, Socolov D, Vasiluță C, Ursache A. Pyoderma Gangrenosum, a Challenging Postpartum Diagnosis—Case Report and Literature Review. Journal of Clinical Medicine. 2024; 13(13):3653. https://doi.org/10.3390/jcm13133653
Chicago/Turabian StyleMatasariu, Daniela Roxana, Iuliana Elena Bujor, Elena Mihălceanu, Tudor Cătălin Gîscă, Alina Stâncanu, Elena Corina Andriescu, Ioana Popescu, Demetra Socolov, Ciprian Vasiluță, and Alexandra Ursache. 2024. "Pyoderma Gangrenosum, a Challenging Postpartum Diagnosis—Case Report and Literature Review" Journal of Clinical Medicine 13, no. 13: 3653. https://doi.org/10.3390/jcm13133653
APA StyleMatasariu, D. R., Bujor, I. E., Mihălceanu, E., Gîscă, T. C., Stâncanu, A., Andriescu, E. C., Popescu, I., Socolov, D., Vasiluță, C., & Ursache, A. (2024). Pyoderma Gangrenosum, a Challenging Postpartum Diagnosis—Case Report and Literature Review. Journal of Clinical Medicine, 13(13), 3653. https://doi.org/10.3390/jcm13133653