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Impact of Acid Suppression Therapy on Renal and Survival Outcomes in Patients with Chronic Kidney Disease: A Taiwanese Nationwide Cohort Study
 
 
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Volume 12
Issue 1
10.3390/jcm12010072
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Comment
Peer-Review Record

Drug–Drug Interactions, Medication Adherence, and Stroke Should Be Considered When Approaching the Impact of Acid Suppression Therapy on Chronic Kidney Disease Patients. Comment on Chen et al. Impact of Acid Suppression Therapy on Renal and Survival Outcomes in Patients with Chronic Kidney Disease: A Taiwanese Nationwide Cohort Study. J. Clin. Med. 2022, 11, 5612

J. Clin. Med. 2023, 12(1), 72; https://doi.org/10.3390/jcm12010072
by Ai-Hsien Li 1,2,* and Yen-Ling Chiu 1,2
Reviewer 1:
Corina Daniela Ene
Reviewer 2: Anonymous
J. Clin. Med. 2023, 12(1), 72; https://doi.org/10.3390/jcm12010072
Submission received: 6 November 2022 / Revised: 15 December 2022 / Accepted: 19 December 2022 / Published: 22 December 2022
(This article belongs to the Special Issue Clinical Management on Chronic Kidney Disease)

Round 1

Reviewer 1 Report

The answer is well documented but in my opinion, there would be necessary more comparisons with other studies from literature.

Author Response

Thanks for reviewer's valuable opinions.

Based on these, we revised our manuscript and added 2 more studies for comparison in the literature. The first one (reference 8) is to address the medication compliance in CKD patients, and it could be another confounding factor of this study which the authors already admitted. The second one (Reference 9) mentioned a similar outcome advantage of H2RA over PPI in another patient group with critical illness. 

We appreciate your opinions again. 

Reviewer 2 Report

I believe that, in the interests of the quality and scientific integrity of the Journal of Clinical Medicine, the submitted commentary may be published provided that it will include a response from the authors of the manuscript to which it relates (Yi-Chun Chen, Yen-Chun Chen, Wen-Yen Chiou and Ben-Hui Yu 'Impact of Acid-Suppression Therapy on Renal and Survival Outcomes in Patients with Chronic Kidney Disease: A Taiwanese Nationwide Cohort Study').

Author Response

Response to Reviewer 2 Comments:

We strongly agree with your valuable opinions and are looking forward to the authors of the original article related to our commentary providing their responses. 

We appreciate your opinions again. 

Round 2

Reviewer 2 Report

I recommend a "Comment" on the publication.

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