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Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Non-Traumatic Cardiac Arrest: A Narrative Review of Known and Potential Physiological Effects

Department of Anesthesia, Intensive Care and Prehospital Emergency, Ospedale Maggiore Carlo Alberto Pizzardi, 40133 Bologna, Italy
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Academic Editor: Toshiaki Iba
J. Clin. Med. 2022, 11(3), 742; https://doi.org/10.3390/jcm11030742
Received: 10 January 2022 / Revised: 24 January 2022 / Accepted: 27 January 2022 / Published: 29 January 2022
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is widely used in acute trauma care worldwide and has recently been proposed as an adjunct to standard treatments during cardiopulmonary resuscitation in patients with non-traumatic cardiac arrest (NTCA). Several case series have been published highlighting promising results, and further trials are starting. REBOA during CPR increases cerebral and coronary perfusion pressure by increasing the afterload of the left ventricle, thus improving the chances of ROSC and decreasing hypoperfusion to the brain. In addition, it may facilitate the termination of malignant arrhythmias by stimulating baroreceptor reflex. Aortic occlusion could mitigate the detrimental neurological effects of adrenaline, not only by increasing cerebral perfusion but also reducing the blood dilution of the drug, allowing the use of lower doses. Finally, the use of a catheter could allow more precise hemodynamic monitoring during CPR and a faster transition to ECPR. In conclusion, REBOA in NTCA is a feasible technique also in the prehospital setting, and its use deserves further studies, especially in terms of survival and good neurological outcome, particularly in resource-limited settings. View Full-Text
Keywords: REBOA; non-traumatic cardiac arrest; cardiopulmonary resuscitation; aortic occlusion; ROSC REBOA; non-traumatic cardiac arrest; cardiopulmonary resuscitation; aortic occlusion; ROSC
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MDPI and ACS Style

Mazzoli, C.A.; Chiarini, V.; Coniglio, C.; Lupi, C.; Tartaglione, M.; Gamberini, L.; Semeraro, F.; Gordini, G. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Non-Traumatic Cardiac Arrest: A Narrative Review of Known and Potential Physiological Effects. J. Clin. Med. 2022, 11, 742. https://doi.org/10.3390/jcm11030742

AMA Style

Mazzoli CA, Chiarini V, Coniglio C, Lupi C, Tartaglione M, Gamberini L, Semeraro F, Gordini G. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Non-Traumatic Cardiac Arrest: A Narrative Review of Known and Potential Physiological Effects. Journal of Clinical Medicine. 2022; 11(3):742. https://doi.org/10.3390/jcm11030742

Chicago/Turabian Style

Mazzoli, Carlo A., Valentina Chiarini, Carlo Coniglio, Cristian Lupi, Marco Tartaglione, Lorenzo Gamberini, Federico Semeraro, and Giovanni Gordini. 2022. "Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Non-Traumatic Cardiac Arrest: A Narrative Review of Known and Potential Physiological Effects" Journal of Clinical Medicine 11, no. 3: 742. https://doi.org/10.3390/jcm11030742

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