Oral Self-Mutilation in Lesch–Nyhan Patients: A Cross-Sectional Study
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Self-Injury Behavior
3.2. Treatment for Self-Injury
4. Discussion
5. Conclusions
- Self-injury behavior in Lesch–Nyhan patients represents a severe management problem that both parents and oral health carers have to face. The incidence of SIB reported is 74% and led to permanent damages in 86% of cases. Among different therapeutical options, including oral appliances and drug administration, dental extraction is the most frequently chosen therapy (71%) despite its invasive approach;
- This cross-sectional study shows how extraction therapy is extremely distressing for patients and suggests that the use of orthodontic appliances reported in the literature should be preferred wherever possible in order to improve the patients’ quality of life.
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Year of birth |
Age at Lesch–Nyhan Syndrome diagnosis |
Presence/absence of self-injury |
First form of self-injury |
Presence/absence of oral SIB |
Type of oral SIB |
Presence/absence of permanent oral lesions |
Type of permanent lesions |
Treatment for oral SIB |
Extractions |
Age at which extractions were performed |
Drugs |
Orthodontic appliances |
Dental check-ups |
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Isola, G.; Piccardo, I.; De Mari, A.; Alberti, G.; Migliorati, M. Oral Self-Mutilation in Lesch–Nyhan Patients: A Cross-Sectional Study. J. Clin. Med. 2022, 11, 5981. https://doi.org/10.3390/jcm11205981
Isola G, Piccardo I, De Mari A, Alberti G, Migliorati M. Oral Self-Mutilation in Lesch–Nyhan Patients: A Cross-Sectional Study. Journal of Clinical Medicine. 2022; 11(20):5981. https://doi.org/10.3390/jcm11205981
Chicago/Turabian StyleIsola, Gaetano, Ilaria Piccardo, Anna De Mari, Giorgio Alberti, and Marco Migliorati. 2022. "Oral Self-Mutilation in Lesch–Nyhan Patients: A Cross-Sectional Study" Journal of Clinical Medicine 11, no. 20: 5981. https://doi.org/10.3390/jcm11205981