Next Article in Journal
Valproic Acid-Induced Liver Injury: A Case-Control Study from a Prospective Pharmacovigilance Program in a Tertiary Hospital
Previous Article in Journal
Diagnosis of Pancreatic Ductal Adenocarcinoma by Immuno-Positron Emission Tomography
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 10
Issue 6
10.3390/jcm10061152
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review

by
Shilpa Bhandi
1,
Deepak Mehta
2,
Mohammed Mashyakhy
1,
Hitesh Chohan
1,
Luca Testarelli
3,*,
Jacob Thomas
4,
Harnoor Dhillon
5,
A. Thirumal Raj
6,
Thodur Madapusi Balaji
7,
Saranya Varadarajan
6 and
Shankargouda Patil
8
1
Department of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan 45412, Saudi Arabia
2
Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates
3
Department of Oral and Maxillo Facial Sciences, Univerisity of Rome “La Sapienza”, 00161 Rome, Italy
4
Private Dental Practice, Kochi 682019, India
5
Private Dental Practice, Delhi 110075, India
6
Department of Oral Pathology and Microbiology, Sri Venkateswara Dental College and Hospital, Chennai 600130, India
7
Department of Dentistry, Bharathirajaa Hospital, and Research Institute, Chennai 600017, India
8
Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2021, 10(6), 1152; https://doi.org/10.3390/jcm10061152
Submission received: 21 February 2021 / Revised: 5 March 2021 / Accepted: 8 March 2021 / Published: 10 March 2021
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Browse Figure
Review Reports Versions Notes

Abstract

Removal of microbes is imperative during endodontic therapy. Due to their antimicrobial property, silver nanoparticles have been used for endodontic irrigation of the root canals. The objective of the present study was to provide a qualitative analysis of the published literature assessing silver nanoparticles as root canal irrigants. A search of PubMed, SCOPUS, Web of Science, and Embase databases was done without any time restriction. Articles published in English were included. Data were extracted and the risk of bias was assessed. Of the 154 studies identified, after screening according to the inclusion criteria, five in vitro studies were included. The results indicate that silver nanoparticles have an anti-microbial effect to varying degrees depending on certain factors. Within the limitations of the present studies that have a moderate to low risk of bias, an antimicrobial effect of silver nanoparticles is observed. Silver nanoparticles have the potential to be used as endodontic irrigants, although their efficacy depends on particle size and the duration of contact which require further investigation.
Keywords: silver nanoparticles; antimicrobials; root canal; irrigant; endodontics silver nanoparticles; antimicrobials; root canal; irrigant; endodontics

Share and Cite

MDPI and ACS Style

Bhandi, S.; Mehta, D.; Mashyakhy, M.; Chohan, H.; Testarelli, L.; Thomas, J.; Dhillon, H.; Raj, A.T.; Madapusi Balaji, T.; Varadarajan, S.; et al. Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review. J. Clin. Med. 2021, 10, 1152. https://doi.org/10.3390/jcm10061152

AMA Style

Bhandi S, Mehta D, Mashyakhy M, Chohan H, Testarelli L, Thomas J, Dhillon H, Raj AT, Madapusi Balaji T, Varadarajan S, et al. Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review. Journal of Clinical Medicine. 2021; 10(6):1152. https://doi.org/10.3390/jcm10061152

Chicago/Turabian Style

Bhandi, Shilpa, Deepak Mehta, Mohammed Mashyakhy, Hitesh Chohan, Luca Testarelli, Jacob Thomas, Harnoor Dhillon, A. Thirumal Raj, Thodur Madapusi Balaji, Saranya Varadarajan, and et al. 2021. "Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review" Journal of Clinical Medicine 10, no. 6: 1152. https://doi.org/10.3390/jcm10061152

APA Style

Bhandi, S., Mehta, D., Mashyakhy, M., Chohan, H., Testarelli, L., Thomas, J., Dhillon, H., Raj, A. T., Madapusi Balaji, T., Varadarajan, S., & Patil, S. (2021). Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review. Journal of Clinical Medicine, 10(6), 1152. https://doi.org/10.3390/jcm10061152

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop