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Article

Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study

1
Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan
2
Department of Emergency and Critical Care Medicine, Hitachi General Hospital, 2-1-1, Jonantyo, Hitachi, Ibaraki 3170077, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Michael Christ
J. Clin. Med. 2021, 10(4), 618; https://doi.org/10.3390/jcm10040618
Received: 30 December 2020 / Revised: 1 February 2021 / Accepted: 3 February 2021 / Published: 6 February 2021
It is unclear when to begin rehabilitation after coronary artery bypass grafting (CABG) in the intensive care unit (ICU). Using the Japanese Diagnosis Procedure Combination inpatient database from 2010 to 2018, we identified adult patients who underwent a CABG and who were admitted to the ICU for ≥3 consecutive days from the date of their CABG. Patients who started any rehabilitation program prescribed by physicians or therapists within 3 days of CABG were defined as the early rehabilitation group, and the remaining patients were defined as the usual care group. We identified 30,568 eligible patients, with 13,150 (43%) patients in the early rehabilitation group. An inverse probability of treatment weighting analyses showed that the Barthel Index score at discharge in the early rehabilitation group was significantly higher than that in the usual care group (difference: 3.2; 95% confidence interval: 1.5–4.8). The early rehabilitation group had significantly lower in-hospital mortality, total hospitalization costs, length of ICU stay, and hospital stay vs. the usual care group. Our results suggested that early rehabilitation by physicians or therapists beginning within 3 days of CABG was safe, as suggested by the low mortality and improved physical function in patients who underwent CABG. View Full-Text
Keywords: rehabilitation; physical impairments; coronary artery bypass grafting; intensive care unit; post-intensive care syndrome; observational study rehabilitation; physical impairments; coronary artery bypass grafting; intensive care unit; post-intensive care syndrome; observational study
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MDPI and ACS Style

Ohbe, H.; Nakamura, K.; Uda, K.; Matsui, H.; Yasunaga, H. Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study. J. Clin. Med. 2021, 10, 618. https://doi.org/10.3390/jcm10040618

AMA Style

Ohbe H, Nakamura K, Uda K, Matsui H, Yasunaga H. Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study. Journal of Clinical Medicine. 2021; 10(4):618. https://doi.org/10.3390/jcm10040618

Chicago/Turabian Style

Ohbe, Hiroyuki, Kensuke Nakamura, Kazuaki Uda, Hiroki Matsui, and Hideo Yasunaga. 2021. "Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study" Journal of Clinical Medicine 10, no. 4: 618. https://doi.org/10.3390/jcm10040618

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