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Article

Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview

by
Carmine Zoccali
1,*,
Mariangela Novello
2,
Francesco Arrigoni
3,
Alessandra Scotto di Uccio
4,
Dario Attala
2 and
Virginia Ferraresi
5
1
Oncological Orthopaedics Department, IRCCS—Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy
2
Pathology Department, IRCCS—Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy
3
Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Via Vetoio 1, 67100 L’Aquila, Italy
4
Hepato-Biliary and Organ Transplant Unit, School of General Surgery, Sapienza University, Viale del Policlinico 155, 00161 Rome, Italy
5
Oncology Department, IRCCS—Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2021, 10(20), 4645; https://doi.org/10.3390/jcm10204645
Submission received: 10 August 2021 / Revised: 4 October 2021 / Accepted: 8 October 2021 / Published: 10 October 2021

Abstract

Background: osteoblastoma is a bone-forming tumor accounting for about 1% of all primary bone tumors and 3% of benign bone tumors. The gold-standard treatment is surgical excision; nevertheless, minimally invasive radiological techniques such as thermoablation and, more recently, high intensity focused ultrasound are gaining more importance. The aim of the present paper is to analyze surgical indications based on our experience and on the evidences in the literature. Methods: all patients affected by osteoblastoma who underwent surgical excision in January 2009 and December 2018 were reviewed; eleven patients were enrolled in the study. The epidemiological aspects, size of the disease and site of onset, symptoms, surgery type, indications, and results are reported for every case. Results: all treatments were based on a preoperative diagnosis; pain was constant in all cases. Intralesional surgeries were performed in 9 out of 11 cases; the remaining 2 cases underwent wide resection. No early or late complications occurred after the surgical procedure. The indications for surgery were lesions very close to nerves or joints, unclear diagnosis, risk of fracture, lesion too large for radiofrequency thermoablation, or failure of minimally invasive treatments. At a medium follow-up of 88 months, no local recurrences were verified. Conclusions: osteoblastoma is a rare tumor with difficult diagnosis. Identification is based on symptoms, imaging, and histology. When possible, minimally invasive techniques is preferred for treatment but surgery is still considered the gold standard.
Keywords: osteoblastoma; radiofrequency thermoablation; cryotherapy; benign bone tumor osteoblastoma; radiofrequency thermoablation; cryotherapy; benign bone tumor

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MDPI and ACS Style

Zoccali, C.; Novello, M.; Arrigoni, F.; Scotto di Uccio, A.; Attala, D.; Ferraresi, V. Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview. J. Clin. Med. 2021, 10, 4645. https://doi.org/10.3390/jcm10204645

AMA Style

Zoccali C, Novello M, Arrigoni F, Scotto di Uccio A, Attala D, Ferraresi V. Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview. Journal of Clinical Medicine. 2021; 10(20):4645. https://doi.org/10.3390/jcm10204645

Chicago/Turabian Style

Zoccali, Carmine, Mariangela Novello, Francesco Arrigoni, Alessandra Scotto di Uccio, Dario Attala, and Virginia Ferraresi. 2021. "Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview" Journal of Clinical Medicine 10, no. 20: 4645. https://doi.org/10.3390/jcm10204645

APA Style

Zoccali, C., Novello, M., Arrigoni, F., Scotto di Uccio, A., Attala, D., & Ferraresi, V. (2021). Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview. Journal of Clinical Medicine, 10(20), 4645. https://doi.org/10.3390/jcm10204645

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