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Review

An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times

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Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain
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Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain
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Department of Obstetrics and Gynecology, University Hospital Gregorio Marañón, 28009 Madrid, Spain
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Health Research Institute Gregorio Marañón, 28009 Madrid, Spain
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First of May Health Centre, Health Area I, Rivas Vaciamadrid, 28521 Madrid, Spain
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Service of Pediatric, Hospital Universitario Principe de Asturias, 28801 Alcalá de Henares, Spain
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Unit of Biochemistry and Molecular Biology (CIBEREHD), Department of System Biology, University of Alcalá, 28801 Alcalá de Henares, Spain
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Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain
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Department of Surgery, Medical and Social Sciences, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcala de Henares, Spain
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Los fresnos of Health Centre, Health Area III, Torrejon de Ardoz, 28850 Madrid, Spain
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Immune System Diseases-Rheumatology, Oncology Service an Internal Medicine, University Hospital Príncipe de Asturias, (CIBEREHD), 28806 Alcalá de Henares, Spain
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Department of Psychiatry and Medical Psychology, Hospital Universitario Infanta Leonor, 28031 Madrid, Spain
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Cancer Registry and Pathology Department, Hospital Universitario Principe de Asturias, 28806 Alcalá de Henares, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Ralph A. Tripp
Vaccines 2021, 9(5), 433; https://doi.org/10.3390/vaccines9050433
Received: 9 April 2021 / Revised: 21 April 2021 / Accepted: 22 April 2021 / Published: 27 April 2021
Since the worldwide COVID-19 pandemic was declared a year ago, the search for vaccines has become the top priority in order to restore normalcy after 2.5 million deaths worldwide, overloaded sanitary systems, and a huge economic burden. Vaccine development has represented a step towards the desired herd immunity in a short period of time, owing to a high level of investment, the focus of researchers, and the urge for the authorization of the faster administration of vaccines. Nevertheless, this objective may only be achieved by pursuing effective strategies and policies in various countries worldwide. In the present review, some aspects involved in accomplishing a successful vaccination program are addressed, in addition to the importance of vaccination in a pandemic in the face of unwillingness, conspiracy theories, or a lack of information among the public. Moreover, we provide some updated points related to the landscape of the clinical development of vaccine candidates, specifically, the top five vaccines that are already being assessed in Phase IV clinical trials (BNT162b2, mRNA-1273, AZD1222, Ad26.COV2.S, and CoronaVac). View Full-Text
Keywords: SARS-CoV-2; coronavirus; COVID-19; vaccination programs; vaccine acceptance; vaccine hesitancy; pandemic management; mRNA vaccines; adenovirus-based vaccines; inactivated virus vaccines SARS-CoV-2; coronavirus; COVID-19; vaccination programs; vaccine acceptance; vaccine hesitancy; pandemic management; mRNA vaccines; adenovirus-based vaccines; inactivated virus vaccines
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MDPI and ACS Style

García-Montero, C.; Fraile-Martínez, O.; Bravo, C.; Torres-Carranza, D.; Sanchez-Trujillo, L.; Gómez-Lahoz, A.M.; Guijarro, L.G.; García-Honduvilla, N.; Asúnsolo, A.; Bujan, J.; Monserrat, J.; Serrano, E.; Álvarez-Mon, M.; De León-Luis, J.A.; Álvarez-Mon, M.A.; Ortega, M.A. An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times. Vaccines 2021, 9, 433. https://doi.org/10.3390/vaccines9050433

AMA Style

García-Montero C, Fraile-Martínez O, Bravo C, Torres-Carranza D, Sanchez-Trujillo L, Gómez-Lahoz AM, Guijarro LG, García-Honduvilla N, Asúnsolo A, Bujan J, Monserrat J, Serrano E, Álvarez-Mon M, De León-Luis JA, Álvarez-Mon MA, Ortega MA. An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times. Vaccines. 2021; 9(5):433. https://doi.org/10.3390/vaccines9050433

Chicago/Turabian Style

García-Montero, Cielo, Oscar Fraile-Martínez, Coral Bravo, Diego Torres-Carranza, Lara Sanchez-Trujillo, Ana M. Gómez-Lahoz, Luis G. Guijarro, Natalio García-Honduvilla, Angel Asúnsolo, Julia Bujan, Jorge Monserrat, Encarnación Serrano, Melchor Álvarez-Mon, Juan A. De León-Luis, Miguel A. Álvarez-Mon, and Miguel A. Ortega. 2021. "An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times" Vaccines 9, no. 5: 433. https://doi.org/10.3390/vaccines9050433

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