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Review

Perspectives on New Vaccines against Arboviruses Using Insect-Specific Viruses as Platforms

1
Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, 1945 SW 16th Ave, Gainesville, FL 32608, USA
2
Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ministry of Health, Rodovia BR-316, Km 7, s/n, Ananindeua, 67030-000 Para, Brazil
*
Authors to whom correspondence should be addressed.
Academic Editors: Berlin Londono-Renteria and Guillermo Rua-Uribe
Vaccines 2021, 9(3), 263; https://doi.org/10.3390/vaccines9030263
Received: 8 February 2021 / Revised: 7 March 2021 / Accepted: 13 March 2021 / Published: 16 March 2021
(This article belongs to the Special Issue Study on the Prevention and Treatment of Arbovirus)
Arthropod-borne viruses (arboviruses) are global pathogens circulating endemically with local explosive outbreaks and constant encroachment into new locations. Few vaccines against arboviruses exist; most for humans are in development or clinical trials. Insect-specific viruses (ISVs) offer a unique platform for expression of arbovirus proteins, through the creation of ISV/arbovirus chimeras. Studies have shown promising results of these vaccines with several advantages over their wild-type counterparts. In this review, we discuss the current status of these potential vaccines using ISVs. View Full-Text
Keywords: vaccines; insect-specific virus; arbovirus vaccines; insect-specific virus; arbovirus
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MDPI and ACS Style

Carvalho, V.L.; Long, M.T. Perspectives on New Vaccines against Arboviruses Using Insect-Specific Viruses as Platforms. Vaccines 2021, 9, 263. https://doi.org/10.3390/vaccines9030263

AMA Style

Carvalho VL, Long MT. Perspectives on New Vaccines against Arboviruses Using Insect-Specific Viruses as Platforms. Vaccines. 2021; 9(3):263. https://doi.org/10.3390/vaccines9030263

Chicago/Turabian Style

Carvalho, Valéria L., and Maureen T. Long. 2021. "Perspectives on New Vaccines against Arboviruses Using Insect-Specific Viruses as Platforms" Vaccines 9, no. 3: 263. https://doi.org/10.3390/vaccines9030263

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