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The Changing Acceptance of COVID-19 Vaccination in Different Epidemic Phases in China: A Longitudinal Study

by 1,2,†, 1,†, 1,2, 1,2, 1,2, 1,2, 1,2, 3, 3 and 2,4,5,*
School of Public Health, Peking University, Beijing 100083, China
China Center for Health Development Studies, Peking University, Beijing 100083, China
National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Peking University Health Science Center—Chinese Center for Disease Control and Prevention Joint Center for Vaccine Economics, Beijing 100083, China
Key Laboratory of Reproductive Health, National Health Commission of the People’s Republic of China, Beijing 100083, China
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Ralph J. DiClemente
Vaccines 2021, 9(3), 191;
Received: 29 January 2021 / Revised: 20 February 2021 / Accepted: 22 February 2021 / Published: 25 February 2021
(This article belongs to the Special Issue Vaccination and Public Health Version II: COVID-19 Vaccination)
COVID-19 vaccines have been conditionally used in a few countries, including China since December 2020. The present study aimed to examine whether the acceptance of COVID-19 vaccination changed in different COVID-19 epidemic phases in China. Two consecutive surveys were conducted among Chinese adults in March (n = 2058) (severe epidemic phase) and November–December (n = 2013) (well-contained phase, right before the COVID-19 vaccine was conditionally approved) 2020, and 791 respondents were longitudinally followed-up. The attitude, acceptance, and preferences for future COVID-19 vaccination were compared between two epidemic phases. Multivariate logistic regression was used to identify influencing factors of acceptance. Among the 791 respondents longitudinally followed, 91.9% in March and 88.6% of them in November–December 2020 would like to get COVID-19 vaccination in China. In March 58.3% wished to get vaccinated immediately, but the proportion declined to 23.0% in November–December 2020, because more respondents wanted to delay vaccination until the vaccine’s safety was confirmed. Similar results were found by comparing all respondents from the two cross-sectional surveys in different epidemic phases. The risk perception, attitude for the importance of vaccination against COVID-19, vaccination history, valuing doctor’s recommendations, vaccination convenience, or vaccine price in decision-making had impacts on respondents’ intention for immediate vaccination. The public acceptance for COVID-19 vaccination in China sustained at a high level in different COVID-19 epidemic phases. However, the intention of immediate vaccination declined substantially due to concerns about the vaccine’s safety. Information about vaccination safety from authoritative sources, doctor’s recommendations, and vaccination convenience were important in addressing vaccine hesitancy and promoting successful herd immunity for the general population in China. View Full-Text
Keywords: COVID-19; vaccine acceptance; change; China; phase COVID-19; vaccine acceptance; change; China; phase
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MDPI and ACS Style

Wang, J.; Lu, X.; Lai, X.; Lyu, Y.; Zhang, H.; Fenghuang, Y.; Jing, R.; Li, L.; Yu, W.; Fang, H. The Changing Acceptance of COVID-19 Vaccination in Different Epidemic Phases in China: A Longitudinal Study. Vaccines 2021, 9, 191.

AMA Style

Wang J, Lu X, Lai X, Lyu Y, Zhang H, Fenghuang Y, Jing R, Li L, Yu W, Fang H. The Changing Acceptance of COVID-19 Vaccination in Different Epidemic Phases in China: A Longitudinal Study. Vaccines. 2021; 9(3):191.

Chicago/Turabian Style

Wang, Jiahao, Xinran Lu, Xiaozhen Lai, Yun Lyu, Haijun Zhang, Yufei Fenghuang, Rize Jing, Li Li, Wenzhou Yu, and Hai Fang. 2021. "The Changing Acceptance of COVID-19 Vaccination in Different Epidemic Phases in China: A Longitudinal Study" Vaccines 9, no. 3: 191.

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