COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Data Sources and Strategy
2.2. Selection and Eligibility Criteria
2.3. Data Extraction
2.4. Risk of Bias (Quality) Assessment
2.5. Statistical Analysis
3. Results
3.1. Identification and Selection of Studies
3.2. Characteristics of the Studies
3.3. Risk of Bias (Quality) Assessment
3.4. COVID-19 Vaccine Uptake
3.4.1. All Healthcare Workers
3.4.2. Physicians
3.4.3. Nurses
3.5. Predictors of COVID-19 Vaccine Uptake among Healthcare Workers
Reference | Older Age | Males | Married | Higher Educational Level | White Race | Higher Income | Physicians | Work Experience | Chronic Condition |
---|---|---|---|---|---|---|---|---|---|
Choi et al. [32] | - | - | - | - | ↓ | - | - | - | - |
Laiyemo et al. [34] | ↑ | NS | NS | ↑ | NS | - | NS | - | - |
Lucaccioni et al. [35] | ↑ | NS | - | - | - | - | ↑ | - | NS |
Dahie et al. [36] | ↑ | ↑ | - | ↑ | - | - | ↑ | - | NS |
Zdravkovic et al. [37] | ↑ | ↓ | - | - | - | - | ↑ | NS | - |
Agha et al. [38] | - | - | - | ↑ | - | - | ↑ | - | - |
Baniak et al. [39] | NS | NS | NS | - | NS | - | - | NS | - |
Xu et al. [40] | NS | NS | - | NS | - | - | NS | - | - |
Martin et al. [41] | ↑ | ↑ | - | - | ↑ | - | ↓ | - | - |
Farah et al. [43] | ↑ | ↑ | - | - | ↑ | - | ↑ | - | - |
Alya et al. [44] | - | ↑ | ↓ | - | - | ↑ | - | - | - |
Galanis et al. [45] | NS | ↓ | NS | NS | - | NS | NS | NS | NS |
Doran et al. [46] | ↑ | NS | - | - | - | - | NS | - | NS |
Dubov et al. [47] | ↓ | - | - | - | - | - | - | - | - |
Rikitu Terefa et al. [48] | ↑ | ↑ | - | NS | - | NS | NS | - | NS |
Oliver et al. [49] | NS | NS | - | - | ↑ | - | ↑ | - | - |
Bedston et al. [50] | ↑ | NS | - | - | ↑ | - | ↑ | - | - |
Moucheraud et al. [51] | NS | NS | - | - | - | - | NS | - | NS |
Abubakar et al. [54] | ↑ | NS | - | - | - | - | - | - | - |
Gopaul et al. [55] | ↑ | NS | - | - | - | - | ↑ | - | - |
Akech et al. [56] | ↑ | - | - | - | - | - | NS | - | NS |
Positive association a | 12/18 | 5/17 | 0/4 | 3/6 | 4/7 | 1/3 | 8/16 | 0/3 | 0/7 |
Negative association b | 1/18 | 2/17 | 1/4 | 0/6 | 1/7 | 0/3 | 1/16 | 0/3 | 0/7 |
No association c | 5/18 | 10/17 | 3/4 | 3/6 | 2/7 | 2/3 | 7/16 | 3/3 | 7/7 |
Reference | History of SARS-CoV-2 Infection | Higher Severity Perception of COVID-19 | Direct COVID-19 Patient Care | Self-Rated Health Status | Influenza Vaccine | Confidence in COVID-19 Vaccine Effectiveness | Confidence in COVID-19 Vaccine Safety | Knowledge of COVID-19 Vaccines | Information about COVID-19 Vaccines |
---|---|---|---|---|---|---|---|---|---|
Lucaccioni et al. [35] | ↓ | - | NS | NS | ↑ | ↑ | - | - | NS |
Dahie et al. [36] | - | - | ↑ | - | - | - | - | - | - |
Zdravkovic et al. [37] | NS | - | - | - | - | - | - | - | - |
Baniak et al. [39] | - | - | - | - | - | NS | ↑ | NS | NS |
Xu et al. [40] | - | - | - | - | - | - | ↑ | - | - |
Martin et al. [41] | ↓ | - | - | - | - | - | - | - | - |
Farah et al. [43] | ↓ | - | ↑ | - | - | - | - | - | - |
Alya et al. [44] | ↓ | - | - | - | - | - | ↑ | - | - |
Galanis et al. [45] | NS | NS | NS | - | ↑ | ↑ | ↑ | - | - |
Doran et al. [46] | ↓ | NS | ↑ | ↑ | ↑ | NS | ↑ | NS | - |
Dubov et al. [47] | ↓ | - | - | - | - | - | - | - | - |
Rikitu Terefa et al. [48] | - | - | ↑ | NS | - | - | - | - | - |
Oliver et al. [49] | - | - | - | - | ↑ | - | ↑ | - | - |
Abubakar et al. [54] | NS | - | - | - | - | - | - | - | - |
Gopaul et al. [55] | - | - | - | - | - | NS | - | - | - |
Akech et al. [56] | - | ↑ | NS | - | - | - | - | - | - |
Positive association a | 0/9 | 1/3 | 4/7 | 1/3 | 4/4 | 2/5 | 6/6 | 0/2 | 0/2 |
Negative association b | 6/9 | 0/3 | 0/7 | 0/3 | 0/4 | 0/5 | 0/6 | 0/2 | 0/2 |
No association c | 3/9 | 2/3 | 3/7 | 2/3 | 0/4 | 3/5 | 0/6 | 2/2 | 2/2 |
4. Discussion
4.1. COVID-19 Vaccine Uptake
4.2. Predictors of COVID-19 Vaccine Uptake
4.3. Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Worldometer COVID-19 Coronavirus Pandemic. 2022. Available online: https://www.worldometers.info/coronavirus/ (accessed on 28 August 2022).
- Chung, H.-Y.; Jian, M.-J.; Chang, C.-K.; Lin, J.-C.; Yeh, K.-M.; Chen, C.-W.; Hsieh, S.-S.; Hung, K.-S.; Tang, S.-H.; Perng, C.-L.; et al. Emergency SARS-CoV-2 Variants of Concern: Novel Multiplex Real-Time RT-PCR Assay for Rapid Detection and Surveillance. Microbiol. Spectr. 2022, 10, e02513-21. [Google Scholar] [CrossRef] [PubMed]
- Haque, A.; Pant, A.B. Mitigating COVID-19 in the Face of Emerging Virus Variants, Breakthrough Infections and Vaccine Hesitancy. J. Autoimmun. 2022, 127, 102792. [Google Scholar] [CrossRef] [PubMed]
- World Health Organization. The Impact of COVID-19 on Health and Care Workers: A Closer Look at Deaths; World Health Organization: Geneva, Switzerland, 2021; Available online: https://apps.who.int/iris/bitstream/handle/10665/345300/WHO-HWF-WorkingPaper-2021.1-eng.pdf (accessed on 28 August 2022).
- Ferland, L.; Carvalho, C.; Gomes Dias, J.; Lamb, F.; Adlhoch, C.; Suetens, C.; Beauté, J.; Kinross, P.; Plachouras, D.; Hannila-Handelberg, T.; et al. Risk of Hospitalization and Death for Healthcare Workers with COVID-19 in Nine European Countries, January 2020–January 2021. J. Hosp. Infect. 2022, 119, 170–174. [Google Scholar] [CrossRef] [PubMed]
- Martin, C.A.; Patel, P.; Goss, C.; Jenkins, D.R.; Price, A.; Barton, L.; Gupta, P.; Zaccardi, F.; Jerina, H.; Duraisingham, S.; et al. Demographic and Occupational Determinants of Anti-SARS-CoV-2 IgG Seropositivity in Hospital Staff. J. Public Health 2022, 44, 234–245. [Google Scholar] [CrossRef] [PubMed]
- Shah, A.S.V.; Wood, R.; Gribben, C.; Caldwell, D.; Bishop, J.; Weir, A.; Kennedy, S.; Reid, M.; Smith-Palmer, A.; Goldberg, D.; et al. Risk of Hospital Admission with Coronavirus Disease 2019 in Healthcare Workers and Their Households: Nationwide Linkage Cohort Study. BMJ 2020, 371, m3582. [Google Scholar] [CrossRef]
- Gholami, M.; Fawad, I.; Shadan, S.; Rowaiee, R.; Ghanem, H.; Hassan Khamis, A.; Ho, S.B. COVID-19 and Healthcare Workers: A Systematic Review and Meta-Analysis. Int. J. Infect. Dis. 2021, 104, 335–346. [Google Scholar] [CrossRef]
- Gómez-Ochoa, S.A.; Franco, O.H.; Rojas, L.Z.; Raguindin, P.F.; Roa-Díaz, Z.M.; Wyssmann, B.M.; Guevara, S.L.R.; Echeverría, L.E.; Glisic, M.; Muka, T. COVID-19 in Health-Care Workers: A Living Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes. Am. J. Epidemiol. 2021, 190, 161–175. [Google Scholar] [CrossRef]
- Anand, P.; Stahel, V.P. Review the Safety of COVID-19 MRNA Vaccines: A Review. Patient Saf. Surg. 2021, 15, 20. [Google Scholar] [CrossRef]
- Pormohammad, A.; Zarei, M.; Ghorbani, S.; Mohammadi, M.; Razizadeh, M.H.; Turner, D.L.; Turner, R.J. Efficacy and Safety of COVID-19 Vaccines: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Vaccines 2021, 9, 467. [Google Scholar] [CrossRef]
- Liu, Q.; Qin, C.; Liu, M.; Liu, J. Effectiveness and Safety of SARS-CoV-2 Vaccine in Real-World Studies: A Systematic Review and Meta-Analysis. Infect. Dis. Poverty 2021, 10, 132. [Google Scholar] [CrossRef]
- Ma, Y.; Deng, J.; Liu, Q.; Du, M.; Liu, M.; Liu, J. Effectiveness and Safety of COVID-19 Vaccine among Pregnant Women in Real-World Studies: A Systematic Review and Meta-Analysis. Vaccines 2022, 10, 246. [Google Scholar] [CrossRef] [PubMed]
- Biswas, N.; Mustapha, T.; Khubchandani, J.; Price, J.H. The Nature and Extent of COVID-19 Vaccination Hesitancy in Healthcare Workers. J. Community Health 2021, 46, 1244–1251. [Google Scholar] [CrossRef]
- de Albuquerque Veloso Machado, M.; Roberts, B.; Wong, B.L.H.; van Kessel, R.; Mossialos, E. The Relationship between the COVID-19 Pandemic and Vaccine Hesitancy: A Scoping Review of Literature until August 2021. Front. Public Health 2021, 9, 747787. [Google Scholar] [CrossRef] [PubMed]
- Heyerdahl, L.W.; Dielen, S.; Nguyen, T.; Van Riet, C.; Kattumana, T.; Simas, C.; Vandaele, N.; Vandamme, A.-M.; Vandermeulen, C.; Giles-Vernick, T.; et al. Doubt at the Core: Unspoken Vaccine Hesitancy among Healthcare Workers. Lancet Reg. Health Eur. 2022, 12, 100289. [Google Scholar] [CrossRef] [PubMed]
- Bianchi, F.P.; Stefanizzi, P.; Brescia, N.; Lattanzio, S.; Martinelli, A.; Tafuri, S. COVID-19 Vaccination Hesitancy in Italian Healthcare Workers: A Systematic Review and Meta-Analysis. Expert Rev. Vaccines 2022, 21, 1289–1300. [Google Scholar] [CrossRef]
- Peterson, C.J.; Lee, B.; Nugent, K. COVID-19 Vaccination Hesitancy among Healthcare Workers—A Review. Vaccines 2022, 10, 948. [Google Scholar] [CrossRef]
- Carter, B.; Collins, J.T.; Barlow-Pay, F.; Rickard, F.; Bruce, E.; Verduri, A.; Quinn, T.J.; Mitchell, E.; Price, A.; Vilches-Moraga, A.; et al. Nosocomial COVID-19 Infection: Examining the Risk of Mortality. The COPE-Nosocomial Study (COVID in Older PEople). J. Hosp. Infect. 2020, 106, 376–384. [Google Scholar] [CrossRef]
- Moynan, D.; Cagney, M.; Dhuthaigh, A.N.; Foley, M.; Salter, A.; Reidy, N.; Reidy, P.; de Barra, E.; Fitzpatrick, F. The Role of Healthcare Staff COVID-19 Screening in Infection Prevention & Control. J. Infect. 2020, 81, e53–e54. [Google Scholar] [CrossRef]
- Galanis, P.; Vraka, I.; Fragkou, D.; Bilali, A.; Kaitelidou, D. Intention of Healthcare Workers to Accept COVID-19 Vaccination and Related Factors: A Systematic Review and Meta-Analysis. Asian Pac. J. Trop. Med. 2021, 14, 543. [Google Scholar] [CrossRef]
- Shui, X.; Wang, F.; Li, L.; Liang, Q. COVID-19 Vaccine Acceptance among Healthcare Workers in China: A Systematic Review and Meta-Analysis. PLoS ONE 2022, 17, e0273112. [Google Scholar] [CrossRef]
- Luo, C.; Yang, Y.; Liu, Y.; Zheng, D.; Shao, L.; Jin, J.; He, Q. Intention to COVID-19 Vaccination and Associated Factors among Health Care Workers: A Systematic Review and Meta-Analysis of Cross-Sectional Studies. Am. J. Infect. Control 2021, 49, 1295–1304. [Google Scholar] [CrossRef] [PubMed]
- Ackah, M.; Ameyaw, L.; Gazali Salifu, M.; Afi Asubonteng, D.P.; Osei Yeboah, C.; Narkotey Annor, E.; Abena Kwartemaa Ankapong, E.; Boakye, H. COVID-19 Vaccine Acceptance among Health Care Workers in Africa: A Systematic Review and Meta-Analysis. PLoS ONE 2022, 17, e0268711. [Google Scholar] [CrossRef]
- Desye, B. Prevalence and Determinants of COVID-19 Vaccine Acceptance Among Healthcare Workers: A Systematic Review. Front. Public Health 2022, 10, 941206. [Google Scholar] [CrossRef] [PubMed]
- Moher, D.; Liberati, A.; Tetzlaff, J.; Altman, D.G. The PRISMA Group Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med. 2009, 6, e1000097. [Google Scholar] [CrossRef]
- Santos, W.M.; Secoli, S.R.; Püschel, V.A. The Joanna Briggs Institute Approach for Systematic Reviews. Rev. Latino-Am. Enferm. 2018, 26, e3074. [Google Scholar] [CrossRef]
- Barendregt, J.J.; Doi, S.A.; Lee, Y.Y.; Norman, R.E.; Vos, T. Meta-Analysis of Prevalence. J. Epidemiol. Community Health 2013, 67, 974–978. [Google Scholar] [CrossRef]
- Higgins, J.P.T. Measuring Inconsistency in Meta-Analyses. BMJ 2003, 327, 557–560. [Google Scholar] [CrossRef]
- Egger, M.; Smith, G.D.; Schneider, M.; Minder, C. Bias in Meta-Analysis Detected by a Simple, Graphical Test. BMJ 1997, 315, 629–634. [Google Scholar] [CrossRef]
- Wallace, B.C.; Schmid, C.H.; Lau, J.; Trikalinos, T.A. Meta-Analyst: Software for Meta-Analysis of Binary, Continuous and Diagnostic Data. BMC Med. Res. Methodol. 2009, 9, 80. [Google Scholar] [CrossRef]
- Choi, K.; Rondinelli, J.; Cuenca, E.; Lewin, B.; Chang, J.; Luo, Y.X.; Bronstein, D.; Bruxvoort, K. Race/Ethnicity Differences in COVID-19 Vaccine Uptake Among Nurses. J. Transcult. Nurs. 2022, 33, 134–140. [Google Scholar] [CrossRef]
- Halbrook, M.; Gadoth, A.; Martin-Blais, R.; Gray, A.N.; Kashani, S.; Kazan, C.; Kane, B.; Tobin, N.H.; Ferbas, K.G.; Aldrovandi, G.M.; et al. Longitudinal Assessment of Coronavirus Disease 2019 Vaccine Acceptance and Uptake Among Frontline Medical Workers in Los Angeles, California. Clin. Infect. Dis. 2022, 74, 1166–1173. [Google Scholar] [CrossRef] [PubMed]
- Laiyemo, A.O.; Asemota, J.; Deonarine, A.; Aduli, F.; McDonald-Pinkett, S. Minority Healthcare Workers’ Perception of Safety and COVID-19 Vaccination Uptake. J. Gen. Intern. Med. 2022, 37, 1006–1007. [Google Scholar] [CrossRef] [PubMed]
- Lucaccioni, H.; Chakhunashvili, G.; McKnight, C.J.; Zardiashvili, T.; Jorgensen, P.; Pebody, R.; Kissling, E.; Katz, M.A.; Sanodze, L. Sociodemographic and Occupational Factors Associated with Low Early Uptake of COVID-19 Vaccine in Hospital-Based Healthcare Workers, Georgia, March–July 2021. Vaccines 2022, 10, 1197. [Google Scholar] [CrossRef] [PubMed]
- Dahie, H.A.; Mohamoud, J.H.; Adam, M.H.; Garba, B.; Dirie, N.I.; Sh. Nur, M.A.; Mohamed, F.Y. COVID-19 Vaccine Coverage and Potential Drivers of Vaccine Uptake among Healthcare Workers in SOMALIA: A Cross-Sectional Study. Vaccines 2022, 10, 1116. [Google Scholar] [CrossRef]
- Zdravkovic, M.; Popadic, V.; Nikolic, V.; Klasnja, S.; Brajkovic, M.; Manojlovic, A.; Nikolic, N.; Markovic-Denic, L. COVID-19 Vaccination Willingness and Vaccine Uptake among Healthcare Workers: A Single-Center Experience. Vaccines 2022, 10, 500. [Google Scholar] [CrossRef]
- Agha, S.; Chine, A.; Lalika, M.; Pandey, S.; Seth, A.; Wiyeh, A.; Seng, A.; Rao, N.; Badshah, A. Drivers of COVID-19 Vaccine Uptake amongst Healthcare Workers (HCWs) in Nigeria. Vaccines 2021, 9, 1162. [Google Scholar] [CrossRef]
- Baniak, L.M.; Luyster, F.S.; Raible, C.A.; McCray, E.E.; Strollo, P.J. COVID-19 Vaccine Hesitancy and Uptake among Nursing Staff during an Active Vaccine Rollout. Vaccines 2021, 9, 858. [Google Scholar] [CrossRef]
- Xu, B.; Gao, X.; Zhang, X.; Hu, Y.; Yang, H.; Zhou, Y.-H. Real-World Acceptance of COVID-19 Vaccines among Healthcare Workers in Perinatal Medicine in China. Vaccines 2021, 9, 704. [Google Scholar] [CrossRef]
- Martin, C.A.; Marshall, C.; Patel, P.; Goss, C.; Jenkins, D.R.; Ellwood, C.; Barton, L.; Price, A.; Brunskill, N.J.; Khunti, K.; et al. SARS-CoV-2 Vaccine Uptake in a Multi-Ethnic UK Healthcare Workforce: A Cross-Sectional Study. PLoS Med. 2021, 18, e1003823. [Google Scholar] [CrossRef]
- Narayan, P.; Ts, S.K.; Bv, M.M.; Ghorai, P.A.; Rupert, E.; Shetty, D.P. Uptake and Impact of Vaccination against COVID-19 among Healthcare Workers-Evidence from a Multicentre Study. Am. J. Infect. Control. 2022, 50, 361–363. [Google Scholar] [CrossRef]
- Farah, W.; Breeher, L.; Shah, V.; Hainy, C.; Tommaso, C.P.; Swift, M.D. Disparities in COVID-19 Vaccine Uptake among Health Care Workers. Vaccine 2022, 40, 2749–2754. [Google Scholar] [CrossRef] [PubMed]
- Alya, W.A.; Maraqa, B.; Nazzal, Z.; Odeh, M.; Makhalfa, R.; Nassif, A.; Aabed, M. COVID-19 Vaccine Uptake and Its Associated Factors among Palestinian Healthcare Workers: Expectations Beaten by Reality. Vaccine 2022, 40, 3713–3719. [Google Scholar] [CrossRef] [PubMed]
- Galanis, P.; Moisoglou, I.; Vraka, I.; Siskou, O.; Konstantakopoulou, O.; Katsiroumpa, A.; Kaitelidou, D. Predictors of COVID-19 Vaccine Uptake in Healthcare Workers: A Cross-Sectional Study in Greece. J. Occup. Environ. Med. 2022, 64, e191–e196. [Google Scholar] [CrossRef] [PubMed]
- Doran, J.; Seyidov, N.; Mehdiyev, S.; Gon, G.; Kissling, E.; Herdman, T.; Suleymanova, J.; Rehse, A.P.C.; Pebody, R.; Katz, M.A.; et al. Factors Associated with Early Uptake of COVID-19 Vaccination among Healthcare Workers in Azerbaijan, 2021. Influenza Resp. Viruses 2022, 16, 626–631. [Google Scholar] [CrossRef]
- Dubov, A.; Distelberg, B.J.; Abdul-Mutakabbir, J.C.; Peteet, B.; Roberts, L.; Montgomery, S.B.; Rockwood, N.; Patel, P.; Shoptaw, S.; Chrissian, A.A. Racial/Ethnic Variances in COVID-19 Inoculation among Southern California Healthcare Workers. Vaccines 2022, 10, 1331. [Google Scholar] [CrossRef]
- Rikitu Terefa, D.; Shama, A.T.; Feyisa, B.R.; Ewunetu Desisa, A.; Geta, E.T.; Chego Cheme, M.; Tamiru Edosa, A. COVID-19 Vaccine Uptake and Associated Factors Among Health Professionals in Ethiopia. Infect. Drug Resist. 2021, 14, 5531–5541. [Google Scholar] [CrossRef]
- Oliver, K.; Raut, A.; Pierre, S.; Silvera, L.; Boulos, A.; Gale, A.; Baum, A.; Chory, A.; Davis, N.J.; D’Souza, D.; et al. Factors Associated with COVID-19 Vaccine Receipt at Two Integrated Healthcare Systems in New York City: A Cross-Sectional Study of Healthcare Workers. BMJ Open 2022, 12, e053641. [Google Scholar] [CrossRef]
- Bedston, S.; Akbari, A.; Jarvis, C.I.; Lowthian, E.; Torabi, F.; North, L.; Lyons, J.; Perry, M.; Griffiths, L.J.; Owen, R.K.; et al. COVID-19 Vaccine Uptake, Effectiveness, and Waning in 82,959 Health Care Workers: A National Prospective Cohort Study in Wales. Vaccine 2022, 40, 1180–1189. [Google Scholar] [CrossRef]
- Moucheraud, C.; Phiri, K.; Whitehead, H.S.; Songo, J.; Lungu, E.; Chikuse, E.; Phiri, S.; van Oosterhout, J.J.; Hoffman, R.M. Uptake of the COVID-19 Vaccine among Healthcare Workers in Malawi. Int. Health 2022, ihac007. [Google Scholar] [CrossRef]
- Schrading, W.A.; Trent, S.A.; Paxton, J.H.; Rodriguez, R.M.; Swanson, M.B.; Mohr, N.M.; Talan, D.A.; Project COVERED Emergency Department Network; Bahamon, M. Vaccination Rates and Acceptance of SARS-CoV-2 Vaccination among U.S. Emergency Department Health Care Personnel. Acad. Emerg. Med. 2021, 28, 455–458. [Google Scholar] [CrossRef]
- Kraft, K.B.; Elgersma, I.; Lyngstad, T.M.; Elstrøm, P.; Telle, K. COVID-19 Vaccination Rates among Health Care Workers by Immigrant Background. A Nation-Wide Registry Study from Norway; Public and Global Health: New York, NY, USA, 2021. [Google Scholar]
- Abubakar, A.T.; Suleiman, K.; Ahmad, S.I.; Suleiman, S.Y.; Ibrahim, U.B.; Suleiman, B.A.; Haladu, S.A.; Al-Mustapha, A.I.; Abubakar, M.I. Acceptance of COVID-19 Vaccine among Healthcare Workers in Katsina State, Northwest Nigeria; Public and Global Health: New York, NY, USA, 2022. [Google Scholar]
- Gopaul, C.D.; Ventour, D.; Thomas, D. COVID-19 Vaccine Acceptance and Uptake Among Healthcare Workers in Trinidad & Tobago; Public and Global Health: New York, NY, USA, 2022. [Google Scholar]
- Akech, G.M.; Kanyike, A.M.; Nassozi, A.G.; Aguti, B.; Nakawuki, A.W.; Kimbugwe, D.; Kiggundu, J.; Maiteki, R.; Mukyala, D.; Bongomin, F.; et al. COVID-19 Vaccination Uptake and Self-Reported Side Effects among Healthcare Workers in Mbale City Eastern Uganda. medRxiv 2022. [Google Scholar] [CrossRef]
- Our World in Data Coronavirus (COVID-19) Vaccinations. Available online: https://ourworldindata.org/covid-vaccinations (accessed on 28 August 2022).
- Al-Metwali, B.Z.; Al-Jumaili, A.A.; Al-Alag, Z.A.; Sorofman, B. Exploring the Acceptance of COVID-19 Vaccine among Healthcare Workers and General Population Using Health Belief Model. J. Eval. Clin. Pract. 2021, 27, 1112–1122. [Google Scholar] [CrossRef] [PubMed]
- Wang, M.-W.; Wen, W.; Wang, N.; Zhou, M.-Y.; Wang, C.; Ni, J.; Jiang, J.; Zhang, X.; Feng, Z.-H.; Cheng, Y.-R. COVID-19 Vaccination Acceptance Among Healthcare Workers and Non-Healthcare Workers in China: A Survey. Front. Public Health 2021, 9, 709056. [Google Scholar] [CrossRef] [PubMed]
- World Health Organization. Ten Threats to Global Health in 2019; World Health Organization: Geneva, Switzerland, 2020; Available online: https://www.who.int/news-room/spotlight/ten-threats-to-global-health-in-2019 (accessed on 28 August 2022).
- Wang, K.; Wong, E.L.Y.; Ho, K.F.; Cheung, A.W.L.; Chan, E.Y.Y.; Yeoh, E.K.; Wong, S.Y.S. Intention of Nurses to Accept Coronavirus Disease 2019 Vaccination and Change of Intention to Accept Seasonal Influenza Vaccination during the Coronavirus Disease 2019 Pandemic: A Cross-Sectional Survey. Vaccine 2020, 38, 7049–7056. [Google Scholar] [CrossRef] [PubMed]
- Bogart, L.M.; Dong, L.; Gandhi, P.; Klein, D.J.; Smith, T.L.; Ryan, S.; Ojikutu, B.O. COVID-19 Vaccine Intentions and Mistrust in a National Sample of Black Americans. J. Natl. Med. Assoc. 2022, 113, 599–611. [Google Scholar] [CrossRef]
- Paterson, P.; Meurice, F.; Stanberry, L.R.; Glismann, S.; Rosenthal, S.L.; Larson, H.J. Vaccine Hesitancy and Healthcare Providers. Vaccine 2016, 34, 6700–6706. [Google Scholar] [CrossRef]
- Bwire, G.; Ario, A.R.; Eyu, P.; Ocom, F.; Wamala, J.F.; Kusi, K.A.; Ndeketa, L.; Jambo, K.C.; Wanyenze, R.K.; Talisuna, A.O. The COVID-19 Pandemic in the African Continent. BMC Med. 2022, 20, 167. [Google Scholar] [CrossRef]
- Lin, C.; Mullen, J.; Smith, D.; Kotarba, M.; Kaplan, S.J.; Tu, P. Healthcare Providers’ Vaccine Perceptions, Hesitancy, and Recommendation to Patients: A Systematic Review. Vaccines 2021, 9, 713. [Google Scholar] [CrossRef]
- Glampson, B.; Brittain, J.; Kaura, A.; Mulla, A.; Mercuri, L.; Brett, S.; Aylin, P.; Sandall, T.; Goodman, I.; Redhead, J.; et al. North West London COVID-19 Vaccination Programme: Real-World Evidence for Vaccine Uptake and Effectiveness. medRxiv 2021. [Google Scholar] [CrossRef]
- McCabe, S.D.; Hammershaimb, E.A.; Cheng, D.; Shi, A.; Shyr, D.; Shen, S.; Cole, L.D.; Cataldi, J.R.; Allen, W.; Probasco, R.; et al. Unraveling Attributes of COVID-19 Vaccine Hesitancy and Uptake in the U.S.: A Large Nationwide Study. medRxiv 2021. [Google Scholar] [CrossRef]
- Nguyen, L.H.; Joshi, A.D.; Drew, D.A.; Merino, J.; Ma, W.; Lo, C.-H.; Kwon, S.; Wang, K.; Graham, M.S.; Polidori, L.; et al. Racial and Ethnic Differences in COVID-19 Vaccine Hesitancy and Uptake. medRxiv 2021. [Google Scholar] [CrossRef]
- Ayers, C.K.; Kondo, K.K.; Williams, B.E.; Kansagara, D.; Advani, S.M.; Smith, M.; Young, S.; Saha, S. Disparities in H1N1 Vaccination Rates: A Systematic Review and Evidence Synthesis to Inform COVID-19 Vaccination Efforts. J. Gen. Intern. Med. 2021, 36, 1734–1745. [Google Scholar] [CrossRef]
- Burger, A.E.; Reither, E.N.; Mamelund, S.-E.; Lim, S. Black-White Disparities in 2009 H1N1 Vaccination among Adults in the United States: A Cautionary Tale for the COVID-19 Pandemic. Vaccine 2021, 39, 943–951. [Google Scholar] [CrossRef] [PubMed]
- Mills, M.; Rahal, C. COVID-19 Vaccine Deployment: Behaviour, Ethics, Misinformation and Policy Strategies.; Royal Society: London, UK, 2020. [Google Scholar]
- Scientific Advisory Group for Emergencies. Factors Influencing COVID-19 Vaccine Uptake among Minority Ethnic Groups, 17 December 2020; Scientific Advisory Group for Emergencies: London, UK, 2021; Available online: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/952716/s0979-factors-influencing-vaccine-uptake-minority-ethnic-groups.pdf (accessed on 28 August 2022).
- Woolf, K.; McManus, I.C.; Martin, C.A.; Nellums, L.B.; Guyatt, A.L.; Melbourne, C.; Bryant, L.; Gogoi, M.; Wobi, F.; Al-Oraibi, A.; et al. Ethnic Differences in SARS-CoV-2 Vaccine Hesitancy in United Kingdom Healthcare Workers: Results from the UK-REACH Prospective Nationwide Cohort Study. Lancet Reg. Health Eur. 2021, 9, 100180. [Google Scholar] [CrossRef] [PubMed]
- Martin, C.A.; Jenkins, D.R.; Minhas, J.S.; Gray, L.J.; Tang, J.; Williams, C.; Sze, S.; Pan, D.; Jones, W.; Verma, R.; et al. Socio-Demographic Heterogeneity in the Prevalence of COVID-19 during Lockdown Is Associated with Ethnicity and Household Size: Results from an Observational Cohort Study. EClinicalMedicine 2020, 25, 100466. [Google Scholar] [CrossRef] [PubMed]
- Sze, S.; Pan, D.; Nevill, C.R.; Gray, L.J.; Martin, C.A.; Nazareth, J.; Minhas, J.S.; Divall, P.; Khunti, K.; Abrams, K.R.; et al. Ethnicity and Clinical Outcomes in COVID-19: A Systematic Review and Meta-Analysis. EClinicalMedicine 2020, 29–30, 100630. [Google Scholar] [CrossRef] [PubMed]
- Voysey, M.; Clemens, S.A.C.; Madhi, S.A.; Weckx, L.Y.; Folegatti, P.M.; Aley, P.K.; Angus, B.; Baillie, V.L.; Barnabas, S.L.; Bhorat, Q.E.; et al. Safety and Efficacy of the ChAdOx1 NCoV-19 Vaccine (AZD1222) against SARS-CoV-2: An Interim Analysis of Four Randomised Controlled Trials in Brazil, South Africa, and the UK. Lancet 2021, 397, 99–111. [Google Scholar] [CrossRef]
- Razai, M.S.; Osama, T.; McKechnie, D.G.J.; Majeed, A. COVID-19 Vaccine Hesitancy among Ethnic Minority Groups. BMJ 2021, 372, n513. [Google Scholar] [CrossRef]
- American Nurses Association COVID Vaccine Facts for Nurses Survey. Available online: https://covidvaccinefacts4nurses.org/covid-19-survey (accessed on 28 August 2022).
- Gadoth, A.; Halbrook, M.; Martin-Blais, R.; Gray, A.; Tobin, N.H.; Ferbas, K.G.; Aldrovandi, G.M.; Rimoin, A.W. Cross-Sectional Assessment of COVID-19 Vaccine Acceptance Among Health Care Workers in Los Angeles. Ann. Intern. Med. 2021, 174, 882–885. [Google Scholar] [CrossRef]
- Ylitalo, K.R.; Lee, H.; Mehta, N.K. Health Care Provider Recommendation, Human Papillomavirus Vaccination, and Race/Ethnicity in the US National Immunization Survey. Am. J. Public Health 2013, 103, 164–169. [Google Scholar] [CrossRef]
- Zhang, J.; While, A.E.; Norman, I.J. Knowledge and Attitudes Regarding Influenza Vaccination among Nurses: A Research Review. Vaccine 2010, 28, 7207–7214. [Google Scholar] [CrossRef]
- Harrison, J.; Berry, S.; Mor, V.; Gifford, D. “Somebody Like Me”: Understanding COVID-19 Vaccine Hesitancy among Staff in Skilled Nursing Facilities. J. Am. Med. Dir. Assoc. 2021, 22, 1133–1137. [Google Scholar] [CrossRef] [PubMed]
- Kwok, K.O.; Li, K.-K.; Wei, W.I.; Tang, A.; Wong, S.Y.S.; Lee, S.S. Influenza Vaccine Uptake, COVID-19 Vaccination Intention and Vaccine Hesitancy among Nurses: A Survey. Int. J. Nurs. Stud. 2021, 114, 103854. [Google Scholar] [CrossRef]
- Lau, L.H.W.; Lee, S.S.; Wong, N.S. The Continuum of Influenza Vaccine Hesitancy among Nursing Professionals in Hong Kong. Vaccine 2020, 38, 6785–6793. [Google Scholar] [CrossRef] [PubMed]
- Wilson, A.M.; Abney, S.E.; King, M.-F.; Weir, M.H.; López-García, M.; Sexton, J.D.; Dancer, S.J.; Proctor, J.; Noakes, C.J.; Reynolds, K.A. COVID-19 and Use of Non-Traditional Masks: How Do Various Materials Compare in Reducing the Risk of Infection for Mask Wearers? J. Hosp. Infect. 2020, 105, 640–642. [Google Scholar] [CrossRef]
- Nazareno, J.; Yoshioka, E.; Adia, A.C.; Restar, A.; Operario, D.; Choy, C.C. From Imperialism to Inpatient Care: Work Differences of Filipino and White Registered Nurses in the United States and Implications for COVID-19 through an Intersectional Lens. Gender Work Organ. 2021, 28, 1426–1446. [Google Scholar] [CrossRef]
- Di Gennaro, F.; Murri, R.; Segala, F.V.; Cerruti, L.; Abdulle, A.; Saracino, A.; Bavaro, D.F.; Fantoni, M. Attitudes towards Anti-SARS-CoV2 Vaccination among Healthcare Workers: Results from a National Survey in Italy. Viruses 2021, 13, 371. [Google Scholar] [CrossRef] [PubMed]
- Shaw, J.; Stewart, T.; Anderson, K.B.; Hanley, S.; Thomas, S.J.; Salmon, D.A.; Morley, C. Assessment of US Healthcare Personnel Attitudes Towards Coronavirus Disease 2019 (COVID-19) Vaccination in a Large University Healthcare System. Clin. Infect. Dis. 2021, 73, 1776–1783. [Google Scholar] [CrossRef]
- Viswanath, K.; Bekalu, M.; Dhawan, D.; Pinnamaneni, R.; Lang, J.; McLoud, R. Individual and Social Determinants of COVID-19 Vaccine Uptake. BMC Public Health 2021, 21, 818. [Google Scholar] [CrossRef]
- Sheldenkar, A.; Lim, F.; Yung, C.F.; Lwin, M.O. Acceptance and Uptake of Influenza Vaccines in Asia: A Systematic Review. Vaccine 2019, 37, 4896–4905. [Google Scholar] [CrossRef]
- Wang, Q.; Yue, N.; Zheng, M.; Wang, D.; Duan, C.; Yu, X.; Zhang, X.; Bao, C.; Jin, H. Influenza Vaccination Coverage of Population and the Factors Influencing Influenza Vaccination in Mainland China: A Meta-Analysis. Vaccine 2018, 36, 7262–7269. [Google Scholar] [CrossRef] [PubMed]
- Diesel, J.; Sterrett, N.; Dasgupta, S.; Kriss, J.L.; Barry, V.; Vanden Esschert, K.; Whiteman, A.; Cadwell, B.L.; Weller, D.; Qualters, J.R.; et al. COVID-19 Vaccination Coverage Among Adults—United States, 14 December 2020–22 May 2021. MMWR Morb. Mortal. Wkly. Rep. 2021, 70, 922–927. [Google Scholar] [CrossRef] [PubMed]
- Mehraeen, E.; Karimi, A.; Barzegary, A.; Vahedi, F.; Afsahi, A.M.; Dadras, O.; Moradmand-Badie, B.; Seyed Alinaghi, S.A.; Jahanfar, S. Predictors of Mortality in Patients with COVID-19‚A Systematic Review. Eur. J. Integr. Med. 2020, 40, 101226. [Google Scholar] [CrossRef]
- Sepandi, M.; Taghdir, M.; Alimohamadi, Y.; Afrashteh, S.; Hosamirudsari, H. Factors Associated with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Iran. J. Public Health 2020, 49, 1211. [Google Scholar] [CrossRef]
- Anderson, R.M.; Vegvari, C.; Truscott, J.; Collyer, B.S. Challenges in Creating Herd Immunity to SARS-CoV-2 Infection by Mass Vaccination. Lancet 2020, 396, 1614–1616. [Google Scholar] [CrossRef]
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Galanis, P.; Vraka, I.; Katsiroumpa, A.; Siskou, O.; Konstantakopoulou, O.; Katsoulas, T.; Mariolis-Sapsakos, T.; Kaitelidou, D. COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis. Vaccines 2022, 10, 1637. https://doi.org/10.3390/vaccines10101637
Galanis P, Vraka I, Katsiroumpa A, Siskou O, Konstantakopoulou O, Katsoulas T, Mariolis-Sapsakos T, Kaitelidou D. COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis. Vaccines. 2022; 10(10):1637. https://doi.org/10.3390/vaccines10101637
Chicago/Turabian StyleGalanis, Petros, Irene Vraka, Aglaia Katsiroumpa, Olga Siskou, Olympia Konstantakopoulou, Theodoros Katsoulas, Theodoros Mariolis-Sapsakos, and Daphne Kaitelidou. 2022. "COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis" Vaccines 10, no. 10: 1637. https://doi.org/10.3390/vaccines10101637
APA StyleGalanis, P., Vraka, I., Katsiroumpa, A., Siskou, O., Konstantakopoulou, O., Katsoulas, T., Mariolis-Sapsakos, T., & Kaitelidou, D. (2022). COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis. Vaccines, 10(10), 1637. https://doi.org/10.3390/vaccines10101637