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Omega-3 Long-Chain Polyunsaturated Fatty Acids Intake in Children with Attention Deficit and Hyperactivity Disorder

Children’s Mental Health Center, Hospital Arnau de Villanova, 46015 Valencia, Spain
Department of Medicine and Nursing, University of Valencia, 46010 Valencia, Spain
Author to whom correspondence should be addressed.
Brain Sci. 2019, 9(5), 120;
Received: 15 April 2019 / Revised: 10 May 2019 / Accepted: 22 May 2019 / Published: 23 May 2019
PDF [741 KB, uploaded 23 May 2019]


Omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) play a central role in neuronal growth and in the development of the human brain, and a deficiency of these substances has been reported in children with attention deficit hyperactive disorder (ADHD). In this regard, supplementation with omega-3 polyunsaturated fatty acids is used as adjuvant therapy in ADHD. Seafood, particularly fish, and some types of nuts are the main dietary sources of such fatty acids in the Spanish diet. In order to assess the effect of the intake of common foods containing high amounts of omega-3 polyunsaturated fatty acids, a food frequency questionnaire was administered to parents of children with ADHD (N = 48) and to parents of normally developing children (control group) (N = 87), and the intake of dietary omega-3 LC-PUFA, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), was estimated. Children with ADHD consumed fatty fish, lean fish, mollusks, crustaceans, and chicken eggs significantly less often (p < 0.05) than children in the control group. The estimated daily omega-3 LC-PUFA intake (EPA + DHA) was significantly below that recommended by the public health agencies in both groups, and was significantly lower in children with ADHD (p < 0.05, Cohen’s d = 0.45) compared to normally developing children. Dietary intervention to increase the consumption of fish and seafood is strongly advised and it is especially warranted in children with ADHD, since it could contribute to improve the symptoms of ADHD. View Full-Text
Keywords: fish intake; omega-3 fatty acids; nutrients; ADHD; children; diet-deficient fish intake; omega-3 fatty acids; nutrients; ADHD; children; diet-deficient

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Fuentes-Albero, M.; Martínez-Martínez, M.I.; Cauli, O. Omega-3 Long-Chain Polyunsaturated Fatty Acids Intake in Children with Attention Deficit and Hyperactivity Disorder. Brain Sci. 2019, 9, 120.

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