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Prevalence and Incidence of Multiple Sclerosis in Russian Federation: 30 Years of Studies

by Alexey Boyko 1,2,3 and Mikhail Melnikov 1,2,4,*
1
Department of Neurology, Neurosurgery and Medical Genetic, Prirogov Russian National Research Medical University, 1 Ostrovityanova st., Moscow 117997, Russia
2
Department of Neuroimmunology, Federal Center of Brain and Neurotechnology, Federal Medical-Biological Agency of Russia, 1-10 Ostrovityanova st., Moscow 117997, Russia
3
Scientific-Practical Center of Pediatric Psychoneurology, Michurinsky Prospekt 74, Moscow 119602, Russia
4
Laboratory of Clinical Immunology, National Research Center Institute of Immunology, Federal Medical-Biological Agency of Russia, Kashirskoe shosse 24, Moscow 115478, Russia
*
Author to whom correspondence should be addressed.
Brain Sci. 2020, 10(5), 305; https://doi.org/10.3390/brainsci10050305
Received: 14 April 2020 / Revised: 10 May 2020 / Accepted: 15 May 2020 / Published: 18 May 2020
(This article belongs to the Special Issue A Decade of Brain Sciences)
In the Russian Federation, multiple sclerosis prevalence rates vary from 10 to 80 cases per 100,000, depending on region and the nationality of the population. The main characteristics of multiple sclerosis epidemiology in the XX century in this big territory are: (1) steady increase in multiple sclerosis prevalence and incidence rates, maybe because of better diagnosis and treatment, but also changes in environmental/epigenetic risk profile and/or lifestyle factors; (2) increase of the female to male ratio, increase in multiple sclerosis incidence mainly in females; (3) appearance and increasing frequency of multiple sclerosis in ethnic groups, previously free of multiple sclerosis (Northern Tribes, Yakuts and others). The latest data show that in European Russia, the multiple sclerosis prevalence varies from 30 to 80 cases, in Siberia—from 20 to 70 cases, with steady increases, especially in women. View Full-Text
Keywords: multiple sclerosis; epidemiology; prevalence; incidence multiple sclerosis; epidemiology; prevalence; incidence
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Boyko, A.; Melnikov, M. Prevalence and Incidence of Multiple Sclerosis in Russian Federation: 30 Years of Studies. Brain Sci. 2020, 10, 305.

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