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Open AccessFeature PaperReview

Broadband Time Domain Diffuse Optical Reflectance Spectroscopy: A Review of Systems, Methods, and Applications

1
Dipartimento di Fisica, Politecnico di Milano, 20133 Milano, Italy
2
[email protected], IPIC, Tyndall National Institute, Lee Maltings, Dyke Parade, T12R5CP Cork, Ireland
3
Consiglio Nazionale delle Ricerche, Istituto di Fotonica e Nanotecnologie, 20133 Milano, Italy
4
Department of Physics, University College Cork, College Road, T12 K8AF Cork, Ireland
*
Authors to whom correspondence should be addressed.
Appl. Sci. 2019, 9(24), 5465; https://doi.org/10.3390/app9245465
Received: 22 October 2019 / Revised: 25 November 2019 / Accepted: 28 November 2019 / Published: 12 December 2019
This review presents recent developments and a wide overview of broadband time domain diffuse optical spectroscopy (TD-DOS). Various topics including physics of photon migration, advanced instrumentation, methods of analysis, applications covering multiple domains (tissue chromophore, in vivo studies, food, wood, pharmaceutical industry) are elaborated. The key role of standardization and recent studies in that direction are discussed. Towards the end, a brief outlook is presented on the current status and future trends in broadband TD-DOS. View Full-Text
Keywords: biomedical optics; time-of-flight; diffuse optics; NIR spectroscopy; broadband; in vivo; biophotonics; photon migration; time domain biomedical optics; time-of-flight; diffuse optics; NIR spectroscopy; broadband; in vivo; biophotonics; photon migration; time domain
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MDPI and ACS Style

Konugolu Venkata Sekar, S.; Lanka, P.; Farina, A.; Dalla Mora, A.; Andersson-Engels, S.; Taroni, P.; Pifferi, A. Broadband Time Domain Diffuse Optical Reflectance Spectroscopy: A Review of Systems, Methods, and Applications. Appl. Sci. 2019, 9, 5465.

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