Accuracy and Clinical Relevance of Robot-Assisted Implant Surgery: An Umbrella Review
Abstract
1. Introduction
2. Materials and Methods
2.1. Review Design and Reporting
2.2. Information Sources and Search Strategy
- implant/component placement (dental implants),
- navigation/robotics/digital guidance (static and dynamic computer-assisted navigation, surgical navigation, image-guided surgery, augmented reality, accelerometer-based/portable navigation, patient-specific instrumentation, robotic platforms), and
- review design filters (systematic review/meta-analysis).
2.3. Eligibility Criteria:
- Dental: implant placement in partially/fully edentulous jaws, including clinical and experimental accuracy settings (e.g., cadaveric/phantom/resin models) when synthesized within systematic reviews/meta-analyses.
- Robot-assisted platforms (semi-active/active guidance)
- Computer-assisted navigation (static guides; dynamic navigation)
- Augmented reality-guided navigation
- Accelerometer-/inertial sensor-based navigation (portable systems)
- Patient-specific instrumentation (PSI)
- Dental: entry/coronal deviation, apical deviation, angular deviation, global/platform deviation, and related 3D accuracy metrics.
2.4. Study Selection
2.5. Data Extraction and Management
- Bibliographic details (author, year, journal)
- Review characteristics (protocol registration, search dates/databases, eligibility criteria, synthesis approach)
- Number and design of included primary studies; sample size (implants/procedures/patients)
- Technology category (robotic, static, dynamic, AR, accelerometer/portable, PSI)
- Reference standards for accuracy (CBCT/CT, optical scanning, postoperative imaging, coordinate systems)
- Primary and secondary outcomes (accuracy metrics, time, complications, clinical endpoints)
- Subgroup analyses (jaw, flap/flapless, learning curve, device type, orthopedic approach)
- Authors stated limitations and conclusions
2.6. Methodological Quality Appraisal of Included Reviews
2.7. Overlap Management and Synthesis Approach
2.8. Patient and Public Involvement
3. Results
3.1. Selection of Included Studies
3.2. Characteristics of the Included Reviews
3.3. Accuracy Outcomes of Robot-Assisted Implant Surgery
3.4. Secondary Outcomes: Comparison with Non-Robotic Navigation Systems
3.4.1. Static and Dynamic Computer-Assisted Implant Surgery
3.4.2. Augmented Reality-Guided Implant Placement
3.4.3. Operative Efficiency and Safety
3.5. Methodological Quality (AMSTAR 2)
3.6. Certainty of Evidence (ConQual Assessment)
3.7. Overlap of Primary Studies
3.8. Summary of Key Findings
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| Abbreviation | Definition |
| RAIS | Robot-Assisted Implant Surgery |
| CAIS | Computer-Assisted Implant Surgery |
| sCAIS | Static Computer-Assisted Implant Surgery |
| dCAIS | Dynamic Computer-Assisted Implant Surgery |
| r-CAIS | Robotic Computer-Assisted Implant Surgery |
| ADIR | Autonomous Dental Implant Robotics |
| CBCT | Cone-Beam Computed Tomography |
| AR | Augmented Reality |
| PSI | Patient-Specific Instrumentation |
| PRISMA | Preferred Reporting Items for Systematic Reviews and Meta-Analyses |
| JBI | Joanna Briggs Institute |
| AMSTAR 2 | A Measurement Tool to Assess Systematic Reviews 2 |
| ConQual | Confidence in the Qualitative Synthesis of Evidence |
| CI | Confidence Interval |
| SMD | Standardized Mean Difference |
| CCA | Corrected Covered Area |
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| Navigation Modality | Included Review(s) | Accuracy Improvement vs. Freehand | Key Remarks |
|---|---|---|---|
| Robot-assisted implant surgery (RAIS) | Yang [29]; Pozzi [33]; Jain [30] | Yes—highest accuracy reported (sub-millimetric coronal and apical deviation; angular deviation often <2°) | Mechanical constraint minimizes operator-dependent error; reduced variability and fewer outliers; evidence still limited by number of clinical studies |
| Static computer-assisted implant surgery (sCAIS) | Yu [34]; Khaohoen [35]; Khan [31] | Yes—significant reduction in linear and angular deviation | High reproducibility; accuracy dependent on guide stability, manufacturing precision, and workflow execution |
| Dynamic navigation systems (dCAIS) | Yu [34]; Ravipati [32] | Yes—accuracy comparable to sCAIS when learning curve achieved | Real-time intraoperative feedback; accuracy influenced by operator experience and tracking calibration |
| Study Reference | Navigation Technology Evaluated | Review Design | Population/Context | Accuracy Assessment Method | Range of Reported Deviations | Main Accuracy Findings |
|---|---|---|---|---|---|---|
| Yang [29] | Robot-assisted implant surgery (RAIS) vs. static/dynamic CAIS and freehand | Systematic review & meta-analysis | Clinical and preclinical dental implant placement | CBCT-based coronal, apical and angular deviation | Clinical studies: Coronal: 0.6 ± NR mm (95% CI: 0.5–0.8) Apical: 0.7 ± NR mm (95% CI: 0.6–0.8) Angular: 1.6 ± NR° (95% CI: 1.1–2.0) In vitro studies: Coronal: 0.7 ± NR mm (95% CI: 0.6–0.8) Apical: 0.8 ± NR mm (95% CI: 0.6–1.0) Angular: 1.8 ± NR° (95% CI: 1.2–2.5) NR = not reported at pooled level * | RAIS showed significantly lower coronal, apical and angular deviations than static/dynamic CAIS and freehand. |
| Pozzi [33] | Robot-assisted implant surgery | Systematic review & meta-analysis | Clinical dental implant placement | CBCT deviation metrics | Platform: 0.60 mm (95% CI: 0.51–0.70) Apex: 0.63 mm (95% CI: 0.57–0.69) Angular: 1.42° (95% CI: 1.22–1.63) (Meta-analysis, random-effects model; implant-level pooling) ** | Robotic systems demonstrated the highest positioning accuracy and lowest variability among compared techniques, highlighting superior reproducibility despite cost and learning-curve considerations. |
| Jain [30] | RAIS vs. static and dynamic CAIS | Systematic review | Resin mandibular phantom models | CBCT-based deviation analysis | Coronal: ~0.4–1.0 mm Apical: ~0.6–1.2 mm Angular: ~1.2–3.0° *** | Robotic placement demonstrated superior intrinsic accuracy compared with static and dynamic CAIS, with significantly lower angular, coronal and apical deviations. |
| Yu [34] | Robotic implant surgery | Systematic review & meta-analysis | Clinical and preclinical implant placement | CBCT deviation metrics | Coronal: 0.71 mm (95% CI: 0.60–0.82) Apical: 0.83 mm (95% CI: 0.70–0.96) Angular: 1.94° (95% CI: 1.45–2.43) (Random-effects meta-analysis; pooled estimates) | Robotic systems showed higher accuracy than static guides and dynamic navigation, with consistent results across edentulism types. |
| Khaohoen [35] | Static, dynamic and robot-assisted CAIS (sCAIS, dCAIS, rCAIS) | Systematic review & meta-analysis | Clinical dental implant placement | CBCT angular and linear deviation | Coronal: ~0.5–1.0 mm (study-level means; pooled SD/CI not reported) Apical: ~0.6–1.3 mm (study-level means; pooled SD/CI not reported) Angular: ~1.5–3.2° (study-level means; pooled SD/CI not reported) **** | Robot-assisted surgery achieved the lowest deviations, outperforming static and dynamic CAIS. Fully guided protocols were more accurate than pilot-guided approaches. |
| Khan [31] | Robotic CAIS (r-CAIS) vs. static and dynamic CAIS | Systematic review & meta-analysis | Clinical patients and laboratory models | CBCT-based deviation outcomes | In vivo: Coronal: 0.73 ± 0.38 mm (95% CI: NR) Apical: 0.70 ± 0.39 mm (95% CI: NR) Angular: 2.20 ± 1.03° (95% CI: NR) In vitro: Coronal: 0.78 ± 0.50 mm (95% CI: NR) Apical: 0.92 ± 0.52 mm (95% CI: NR) Angular: 1.09 ± 0.49° (95% CI: NR) ***** | r-CAIS showed significantly lower deviations than dynamic CAIS. Evidence comparing r-CAIS with static CAIS was limited due to insufficient direct comparisons. |
| Ravipati [32] | Robot-assisted implant surgery with haptic and visual guidance (serial, parallel, hybrid robots) | Systematic review | Laboratory models | CBCT deviation metrics | Coronal: 0.72 ± 0.68 mm (95% CI: NR) Apical: 0.86 ± 0.92 mm (95% CI: NR) Angular: 1.47 ± 1.61° (95% CI: NR) ****** | Robotic systems were more accurate than static and dynamic CAIS; hybrid robots showed greater stability and precision. |
| Study Reference | Primary Outcome | Robotic/Navigation Characteristics | Direction of Effect | Secondary Outcomes |
|---|---|---|---|---|
| Yang [29] | Coronal, apical, and angular deviation | Robotic arm-guided implant placement with real-time tracking | Significant reduction in deviation vs. non-robotic techniques | Increased setup time; lack of long-term clinical outcomes |
| Pozzi [33] | Implant positioning accuracy | Mechanically constrained robotic guidance | Lowest variability and highest reproducibility | Learning curve and cost considerations highlighted |
| Jain [30] | Accuracy vs. guided surgery | Robotic vs. static/dynamic CAIS | Robotic superiority in precision | No consistent evidence of improved survival or complications |
| Yu [34] | Deviation metrics | Optical tracking (dynamic) vs. static guides | Similar accuracy ranges | Dynamic systems sensitive to operator experience |
| Ravipati [32] | Accuracy of implant placement (entry, exit, and angular deviation) | Robot-assisted implant surgery using CBCT-based virtual planning, optical/electromagnetic tracking, haptic and visual guidance; in vitro phantom and simulated models | Favorable to robotic systems vs. freehand, static guides, and dynamic CAIS (sub-millimetric linear deviations; mean angular deviation ≈ 1.47°) | Workflow variability; dependence on registration and calibration protocols; heterogeneity across robotic systems; evidence limited to in vitro settings |
| Navigation Modality | Clinical Context | Level of Evidence (Umbrella) | Recommendation |
|---|---|---|---|
| Robot-assisted implant surgery (RAIS) | Complex implant placement; proximity to critical anatomical structures; high-precision demand cases | Moderate | Conditional recommendation: superior accuracy demonstrated, but insufficient evidence of improved long-term clinical outcomes |
| Static computer-assisted implant surgery (sCAIS) | Routine and complex dental implant placement; prosthetically driven cases | Moderate–high | Strong recommendation: consistent accuracy improvement and clinical feasibility |
| Dynamic navigation systems (dCAIS) | Implant placement requires intraoperative flexibility or real-time adjustment | Moderate | Conditional recommendation: accuracy comparable to sCAIS when operator experience is adequate |
| Augmented reality (AR)-guided navigation | Experimental or early digital navigation applications; educational settings | Low–moderate | Conditional recommendation: promising accuracy gains, limited clinical validation |
| Freehand implant placement | Simple cases with sufficient anatomical safety margins | — | Reference standard: higher variability compared with guided approaches |
| Navigation Modality | Linear Deviation Reduction | Angular Precision | Outlier Reduction | Workflow Control | Overall Accuracy Gain |
|---|---|---|---|---|---|
| Robot-assisted implant surgery (RAIS) | ✓✓✓ | ✓✓✓ | ✓✓✓ | ✓✓ | ✓✓✓ |
| Static CAIS (sCAIS) | ✓✓✓ | ✓✓✓ | ✓✓ | ✓✓ | ✓✓✓ |
| Dynamic navigation (dCAIS) | ✓✓ | ✓✓✓ | ✓✓ | ✓✓✓ | ✓✓✓ |
| Augmented reality (AR) | ✓ | ✓ | ✓ | ✓✓ | ✓ |
| Freehand surgery | — | — | — | — | — |
| Study Reference | Protocol Registered | Comprehensive Search | Study Selection in Duplicate | Data Extraction in Duplicate | RoB Assessment | RoB Considered in Interpretation | Overall AMSTAR 2 Rating |
|---|---|---|---|---|---|---|---|
| Yang [29] | Yes | Yes | Yes | Yes | Yes | Partial | Moderate |
| Pozzi [33] | Yes | Yes | Yes | Yes | Yes | Yes | High |
| Jain [30] | No | Yes | Yes | Partial | Yes | Partial | Moderate |
| Yu [34] | No | Yes | Yes | Yes | Yes | Partial | Moderate |
| Khaohoen [35] | No | Partial | Yes | Yes | Partial | No | Low |
| Khan [31] | Yes | Yes | Yes | Yes | Yes | Yes | High |
| Ravipati [32] | No | Partial | Yes | Partial | Partial | No | Low |
| Outcome | Studies Contributing | Methodological Limitations | Consistency | Precision | Overall ConQual Confidence |
|---|---|---|---|---|---|
| Coronal deviation | Yang [29]; Pozzi [33]; Jain [30] | Minor | High | Moderate | Moderate–High |
| Apical deviation | Yang [29]; Pozzi [33]; Jain [30] | Minor | High | Moderate | Moderate–High |
| Angular deviation | Yang [29]; Pozzi [33] | Minor | High | Moderate | Moderate–High |
| Outlier reduction | Yang [29]; Pozzi [33] | Moderate | Moderate | Low–Moderate | Moderate |
| Clinical outcomes (survival, complications) | Jain [30]; Ravipati [32] | Major | Low | Low | Low |
| Review Reference | No. of Primary Studies | Unique Studies | Overlap with Other Reviews |
|---|---|---|---|
| Yang [29] | 23 | 14 | High |
| Pozzi [33] | 19 | 12 | High |
| Jain [30] | 15 | 10 | Moderate |
| Yu [34] | 18 | 11 | Moderate |
| Khaohoen [35] | 12 | 8 | Moderate |
| Khan [31] | 21 | 13 | High |
| Ravipati [32] | 10 | 7 | Low–Moderate |
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Basualdo Allende, J.; Campos-Bijit, V.; Morales-Gómez, C.; Díaz, L.; Bersezio, C.; Fernández, E. Accuracy and Clinical Relevance of Robot-Assisted Implant Surgery: An Umbrella Review. Appl. Sci. 2026, 16, 2159. https://doi.org/10.3390/app16042159
Basualdo Allende J, Campos-Bijit V, Morales-Gómez C, Díaz L, Bersezio C, Fernández E. Accuracy and Clinical Relevance of Robot-Assisted Implant Surgery: An Umbrella Review. Applied Sciences. 2026; 16(4):2159. https://doi.org/10.3390/app16042159
Chicago/Turabian StyleBasualdo Allende, Javier, Vanessa Campos-Bijit, Constanza Morales-Gómez, Leonardo Díaz, Cristian Bersezio, and Eduardo Fernández. 2026. "Accuracy and Clinical Relevance of Robot-Assisted Implant Surgery: An Umbrella Review" Applied Sciences 16, no. 4: 2159. https://doi.org/10.3390/app16042159
APA StyleBasualdo Allende, J., Campos-Bijit, V., Morales-Gómez, C., Díaz, L., Bersezio, C., & Fernández, E. (2026). Accuracy and Clinical Relevance of Robot-Assisted Implant Surgery: An Umbrella Review. Applied Sciences, 16(4), 2159. https://doi.org/10.3390/app16042159

