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Review

Addressing Chemophobia: Bridging Misconceptions in Food Chemistry

by
Aida Moreira da Silva
1,2,3 and
Maria João Barroca
1,2,3,*
1
ESAC—Agriculture School of Coimbra, IPC—Polytechnic University of Coimbra, Bencanta, 3045-601 Coimbra, Portugal
2
Molecular Physical-Chemistry—LAQV-REQUIMTE R&D Unit, Department of Chemistry, UC—University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal
3
Linking Landscape, Environment, Agriculture and Food—LEAF R&D Unit, Instituto Superior de Agronomia, UL—University of Lisbon, Tapada da Ajuda, 1349-017 Lisboa, Portugal
*
Author to whom correspondence should be addressed.
Appl. Sci. 2025, 15(11), 6104; https://doi.org/10.3390/app15116104
Submission received: 27 April 2025 / Revised: 21 May 2025 / Accepted: 26 May 2025 / Published: 29 May 2025

Abstract

Chemophobia—the irrational fear of chemicals—is a widespread phenomenon that challenges scientific literacy, public trust in chemistry, and the progress of innovation, especially in food science industries. Rooted in historical events, cultural influences, and psychological biases, chemophobia has been exacerbated by media sensationalism, misleading marketing, and insufficient education. In food advertising, the rise of terms like “chemical-free” or “100% natural” reflects and reinforces consumer fears, often exploiting misconceptions to drive sales. This article explores the historical and social underpinnings of chemophobia, its manifestations in consumer behavior, and its broader impact on science communication and policymaking. It also outlines actionable strategies for educators, scientists, journalists, lawmakers, and public engagement initiatives to address chemophobia effectively. A comprehensive, multidisciplinary approach is proposed to promote scientific literacy, improve public trust in chemistry, and counteract the cultural narratives that perpetuate chemophobia.

1. Introduction

Chemicals are integral to every aspect of life. From the water we drink to the air we breathe, every material substance is made of chemicals. Despite their ubiquity, the word “chemical” often evokes fear and mistrust in the public. Chemophobia, defined as an irrational fear of chemicals, is a growing societal phenomenon that poses challenges to scientific communication, consumer behavior, and public policy. This fear, while not entirely unjustified given the historical context of industrial disasters and chemical misuse, often leads to a distorted understanding of the chemical sciences. People may fail to recognize that chemistry plays a vital role in enhancing the quality, safety, and longevity of modern life [1].
At the heart of chemophobia lies a paradox. While the public often demands products that are “chemical-free” and “natural”, there is little awareness that such terms are scientifically meaningless. All substances, whether natural or synthetic, are made up of chemicals. For example, water—H2O—is a chemical compound essential for life, yet few people would associate it with the negative connotations of the word “chemical”. This paradox is particularly evident in food science, where consumers are increasingly drawn to products marketed as “100% natural”, despite the extensive scientific processes involved in ensuring their safety and quality.
The terms “chemical-free” and “natural” carry different meanings in consumer marketing compared to their scientific interpretations. In consumer marketing, “chemical-free” is a term commonly used to imply that a product is safer, purer, or more environmentally friendly because it contains no synthetic or artificial ingredients. It is often used as a selling point in products such as cosmetics, food, and household cleaners to appeal to chemophobic sentiments. From a scientific standpoint, the term “chemical-free” is inaccurate and misleading, as all matter is composed of chemicals. Water (H2O), oxygen (O2), and even vitamins and proteins are chemicals. Thus, the concept of a substance or product being “free of chemicals” is scientifically meaningless, as it contradicts basic chemical principles. In marketing, “natural” is often used to suggest that a product is wholesome, unprocessed, or free from synthetic substances. However, the term is loosely defined and inconsistently regulated across regions. It may refer to ingredients derived from nature but does not guarantee safety, efficacy, or environmental friendliness. Scientifically, “natural” refers to substances occurring in nature without human intervention. However, natural origin does not equate to safety. Many natural substances are toxic (e.g., arsenic, cyanide, botulinum toxin), while many synthetic substances are safe and beneficial (e.g., ascorbic acid, acetaminophen). The distinction between “natural” and “synthetic” is often a matter of the production method, not the chemical structure or safety profile. This clarification helps reinforce the argument that these terms, while emotionally persuasive, often distort public understanding of chemistry and contribute to chemophobia.
The rise of chemophobia can be attributed to several factors, including the public’s limited scientific literacy, psychological biases, historical events, and the role of media and marketing. As James Kennedy, an Australian chemistry teacher, argued in the book Fighting Chemophobia, the fear of chemicals is frequently exploited by advertisers and activists who leverage emotional appeals to sell products or promote agendas [2].
Food advertising often misrepresents science to align with consumer fears, promoting terms like “chemical-free” or “organic” while vilifying synthetic substances without scientific justification. This has led to widespread misunderstanding, where chemicals are perceived as inherently harmful, and “natural” substances are regarded as universally safe. In addition, media sensationalism amplifies public fears by focusing on isolated cases of chemical misuse or contamination without adequate context. Stories about pesticide residues, industrial spills, or additives in processed foods are often reported in ways that sensationalize risk, neglecting important nuances like dosage, exposure, and regulatory controls. This kind of reporting has a profound impact on public perception, contributing to a culture of mistrust in the chemical sciences, especially in food chemistry.
Chemophobia is not merely an academic or philosophical issue: it has real-world consequences. It undermines public trust in regulatory bodies, discourages the adoption of beneficial innovations, and influences policymaking in ways that are often counterproductive. For example, campaigns against synthetic preservatives could lead to their removal from food products, compromising safety and shelf life without clear benefits to health. This article explores the origins, manifestations, and effects of chemophobia, with a particular emphasis on its influence on food advertising and consumer behavior. This article draws on insights from discussions at the XVII Meeting of Food Chemistry [3], informal debates with peers, and classroom discussions with food science and biotechnology students, as well as articles, namely [4,5,6,7,8,9], and books such as James Kennedy’s Fighting Chemophobia (2018) and other scholarly works and scientific papers. This paper also proposes a multidisciplinary framework to address chemophobia. By integrating educational initiatives, scientific communication, media reform, and policy changes, this framework aims to promote a more informed and rational understanding of chemistry’s role in society.
This article aims to contribute to a deeper understanding of chemophobia and to inform potential strategies for its mitigation. It discusses approaches and methods for educating the public—particularly in the context of food chemistry—so as to counteract chemophobia, especially in light of misleading advertising.

2. Definitions and Origins of Chemophobia

Chemophobia is not a recent phenomenon; its roots can be traced to historical, cultural, and psychological factors. Understanding these origins is essential for devising effective strategies to counteract its influence.
The irrational fear of chemicals, or chemophobia, defined by IUPAC (International Union of Pure and Applied Chemistry), 1993 [10], has deep historical roots that trace back to specific events, technological advancements, and societal changes over the past two centuries. While chemistry as a field has provided innumerable benefits to humanity—such as advances in medicine, agriculture, and materials—its public perception has been shaped by a series of high-profile disasters, environmental controversies, and industrial incidents that have left a lasting mark on societal trust.
Besides the IUPAC definition, chemophobia has been defined in various ways in the literature. Common descriptions include “the fear of chemistry”, “an irrational fear of chemicals”, and “an exaggerated fear of anything ‘chemical’”. Others highlight public concern, such as “the belief that all chemicals are toxic and likely carcinogenic”. Broader definitions describe it as a persistent, irrational fear of chemical substances—especially synthetic ones—often leading to avoidance and hypersensitivity.
In educational contexts, chemophobia can refer to anxiety about chemistry courses or performing experiments.
The earliest recorded use of the term, cited in a 1962 symposium on food protection, defined it as “a spontaneous, negative reaction when people hear the words ‘chemicals’ or ‘chemical company’”. This confirms that the term was already in use by the early 1960s, although the most widely accepted definition remains “the irrational fear of chemicals” [7].

2.1. Historical Roots of Chemophobia

One of the primary drivers of chemophobia was the emergence of large-scale industrial disasters in the 20th century. These incidents highlighted the potential dangers of chemical misuse and had far-reaching consequences for public trust in chemical industries.
The use of chemicals in warfare during the 20th century further deepened public fears. Chemical weapons, such as chlorine gas and mustard gas during World War I, demonstrated the devastating potential of chemical compounds when weaponized. These substances, designed to cause mass casualties, left a lasting impression of chemicals as tools of destruction [11].
In Minamata, Japan, mercury poisoning caused by industrial wastewater discharged by the Chisso Corporation led to severe neurological damage and death in local fishing communities in 1956. The tragedy, widely publicized in the 1960s, served as a stark warning of the dangers of unregulated chemical discharge and further solidified public fear of chemical contamination [12].
The thalidomide pharmaceutical disaster of the 1960s likely played a significant role in fostering chemophobia and increasing skepticism toward the chemical industry [7]. Later, the use of Agent Orange during the Vietnam War—a herbicide contaminated with dioxin—caused widespread health and environmental damage, reinforcing the association between chemicals and harm [13]. Public opposition to chemical warfare and its long-term consequences contributed to the broader mistrust of synthetic chemicals.
Throughout the 20th century, media coverage of chemical disasters and controversies often emphasized their most alarming aspects. Headlines about chemical spills, contaminated water supplies, and toxic waste dumps frequently lacked the scientific context necessary to understand the risks involved. This one-sided reporting amplified public fears and created a perception of chemistry as a dangerous and poorly regulated field [14]. For example, reports on pesticide residues in food often focused on the presence of chemicals rather than their actual concentration, failing to clarify that detected levels were usually far below safety thresholds [15]. Also, new stories about cancer-causing chemicals rarely explain that carcinogenicity is dependent on dosage, exposure duration, and other factors.
The lack of balanced reporting has contributed to a cultural narrative in which chemicals are seen as inherently threatening, reinforcing chemophobia in subsequent generations.
The Green Revolution of the mid-20th century marked a period of rapid agricultural advancement, driven by the introduction of synthetic fertilizers, pesticides, and high-yield crop varieties. While these innovations helped address food shortages and reduce hunger in many parts of the world, they also faced backlash from environmentalists and advocacy groups concerned about their long-term ecological and health impacts [16].
This opposition, while rooted in legitimate concerns, often framed synthetic agricultural inputs as unnatural and dangerous, further entrenching chemophobia in the public discourse. Campaigns promoting organic farming and “natural” food products gained traction during this period, solidifying the association of “natural” with safety and “synthetic” with risk.
The precautionary principle, which advocates for erring on the side of caution when the safety of a substance is uncertain, has become a dominant framework in public policy and risk management. While valuable in preventing harm, this principle can also exacerbate chemophobia by encouraging the belief that all synthetic chemicals are guilty until proven innocent. This mindset, combined with the historical events described above, has made it difficult for the public to differentiate between legitimate concerns and irrational fears.
Rachel Carson’s book titled Silent Spring (1962) highlighted the environmental and health risks associated with the widespread use of synthetic pesticides, particularly dichloro-diphenyl-trichloroethane, DDT [17]. While Carson’s work was instrumental in sparking the environmental movement and advocating for stricter pesticide regulation, it also contributed to the perception of synthetic chemicals as inherently harmful [18]. The ban on DDT in many countries, following public outcry, marked a turning point in how synthetic chemicals are viewed in society.
In the 1970s, the discovery of toxic chemical waste buried beneath a residential neighborhood in Love Canal, New York, led to widespread health issues, including birth defects and cancer. This disaster, which gained national attention, became a rallying cry for environmental activists and reinforced public fears about the dangers of improperly managed chemical waste [19].
The environmental movement’s focus on the negative impacts of synthetic chemicals, while justified in many cases, often lacked nuance. It tended to frame natural substances as inherently safe and synthetic ones as inherently dangerous: a simplification that has persisted in the public discourse.
In Seveso, Italy, an industrial accident released a large quantity of dioxin, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a highly toxic chemical, into the surrounding area in 1976. Although fatalities were minimal, the long-term health impacts, including increased cancer risks and the evacuation of local residents, received significant attention. The incident became a symbol of the risks posed by chemical manufacturing and led to the creation of the EU’s Seveso Directive (Directive 82/501/EEC) for industrial safety [20].
The Bhopal gas tragedy (1984) in India is one of the most infamous examples of chemical accidents. A leak of methyl isocyanate gas from a pesticide plant owned by Union Carbide Corporation caused the deaths of over 3700 people, with tens of thousands more suffering long-term health effects [21]. The scale of the disaster and its portrayal in global media reinforced the perception of chemicals as dangerous and poorly regulated.
These disasters were not only tragic in their immediate consequences but also pivotal in shaping public attitudes toward chemicals. The highly visible nature of such events, coupled with their often catastrophic effects, contributed to a growing mistrust of chemical industries and their products.
Figure 1 highlights some of the previously mentioned events that could have led to the emergence of chemophobia [7].
More recent examples of the troubling effects of chemophobia on human lives include household chemicals, locally produced food, microbiological risks, laboratory safety regulations, family doctors, vaccinations, public perceptions of “chemical-free”, and food additives [22].
As we know, vaccination serves as a preventive protection against infectious diseases, playing a crucial role in the eradication or significant reduction of the incidence of various illnesses, notably smallpox and poliomyelitis in children [23]. Despite the benefits of vaccination, some people reject it for various reasons. Some refuse vaccination in general, while others fear the chemical substances present in vaccines. When this fear is related to chemical substances, we are dealing with a case of chemophobia.
The causes of this type of chemophobia can be diverse, often fuelled by debates, misinformation, and myths from sources that are not always reliable. A common myth is the fear of aluminium present in some vaccines. It is true that certain adjuvants contain aluminium compounds, but it has not been demonstrated that the quantities or forms present are harmful to human health. The limit considered safe for aluminium exposure is 2 milligrams per kilogram of body weight, a value far higher than that found in vaccines [24].
Another example is the study by Andrew Wakefield, published in the British journal The Lancet in 1998, which linked the MMR (measles, mumps, rubella) vaccine to autism in children. This study was later formally declared fraudulent and misleading [25]. Despite the refutation of this association, some parents still distrust the MMR vaccine. These and many other false or distorted pieces of information about vaccination, amplified during the COVID-19 pandemic, generate distrust, both towards chemical substances and information sources. As a result, many individuals begin to adopt chemophobic behaviors and refuse to vaccinate themselves or their children.
Another domain in which chemophobia is frequently observed is that of food additives. These are chemical compounds deliberately incorporated into food products to enhance specific properties such as appearance, palatability, texture, or shelf life [26]. The emergence of chemophobia in this context is often linked to the negative connotation associated with terms like “additive”, “artificial”, or “synthetic”, which tend to evoke distrust among consumers regarding food safety. In contrast, the term “natural” generally elicits positive perceptions and is commonly equated with safety, despite the fact that many natural substances are capable of inducing adverse effects, including allergic reactions and intolerances [27,28]. In the European Union, as well as in other international regulatory contexts, the use of food additives is strictly governed by safety protocols. Each substance must undergo a rigorous scientific evaluation by independent bodies—such as the European Food Safety Authority (EFSA)—before being authorized for use. Approval is contingent on several criteria: demonstrated technological necessity, clear consumer benefit, absence of health risks at estimated levels of exposure, and the lack of viable alternatives [29].
This perception fuels consumer demand for products bearing labels such as “chemical-free” or “no artificial additives”. Such labels are commonly employed as marketing tools aimed at chemophobic audiences. As mentioned above, from a scientific perspective, the term “chemical-free” is a misnomer, as all substances—natural or synthetic—are composed of chemicals. The dichotomy between “natural” and “synthetic” therefore lacks toxicological validity and often misleads rather than informs consumers.

2.2. Psychological Factors: The Underpinnings of Chemophobia

The persistence and prevalence of chemophobia can be largely attributed to innate psychological factors that shape human perception and decision-making. These factors, rooted in evolutionary biology and cognitive psychology, influence how individuals process information about chemicals and assess risks. Understanding these psychological drivers is crucial for addressing chemophobia, as they reveal why the fear of chemicals persists even in the face of scientific evidence.
Human beings have evolved mechanisms to avoid potential threats in their environment, a concept often referred to as the “precautionary principle of evolution”. Early humans relied on their ability to detect and avoid harmful substances such as spoiled food, toxic plants, and contaminated water, as survival often depended on erring on the side of caution. These mechanisms, which were once critical for survival, have persisted into the modern age, but they are often misapplied in today’s chemically enriched world [30].
One manifestation of this evolutionary bias is the tendency to associate unfamiliar or synthetic substances with danger, even when scientific evidence demonstrates their safety. For example, substances with long, complex chemical names are often perceived as more hazardous, even though the complexity of a name has no bearing on the safety or toxicity of the compound. This is why natural products with simple names, such as “honey”, are intuitively seen as safer than synthetic compounds with technical names like “butylated hydroxytoluene”, even when the latter is thoroughly tested and regulated [2].
Humans are naturally predisposed to focus on negative information more than positive information, a phenomenon known as negativity bias. This bias likely evolved as a survival strategy: giving more attention to potential threats than benefits helped early humans avoid harm. In the context of chemophobia, negativity bias causes people to focus disproportionately on the potential risks of chemicals while ignoring their benefits. For instance, while synthetic preservatives extend the shelf life of food and reduce foodborne illnesses, public discourse often fixates on the small, hypothetical risks associated with their use [31].
Another psychological factor driving chemophobia is the naturalness bias, also referred to as the “natural fallacy”. People are more likely to perceive substances derived from nature as safe and beneficial, while those produced synthetically are often viewed as dangerous or harmful. This bias persists even when there is no scientific basis for distinguishing between natural and synthetic chemicals in terms of safety or efficacy [27].
For example, consumers often prefer “natural” remedies over pharmaceutical drugs, even when the former lacks rigorous testing and the latter is scientifically proven to be effective and safe. The naturalness bias is particularly evident in the food industry, where “natural” labels are heavily marketed despite their lack of a clear or regulated definition. This bias leads to irrational fears, as it ignores the reality that nature produces some of the most toxic substances known to science, such as cyanide, arsenic, and botulinum toxin [2].
Heuristics, or mental shortcuts, are another psychological factor contributing to chemophobia. While heuristics allow individuals to make quick decisions in complex situations, they can also lead to cognitive biases and errors in judgment. Several heuristics are particularly relevant to chemophobia.
People tend to judge the likelihood of an event based on how easily examples of it come to mind. For instance, high-profile chemical disasters such as the above mentioned Bhopal gas tragedy or environmental contamination incidents make the risks of chemicals seem more common and severe than they actually are. This cognitive bias leads individuals to overestimate the dangers of chemicals while underestimating their benefits [32].
The representativeness heuristic causes individuals to assess the safety of a chemical based on how well it fits their mental prototype of something harmful. For example, people may associate long, unpronounceable chemical names with industrial hazards, even if the substances in question are harmless food additives. Conversely, simple names or “natural-sounding” terms are more likely to be perceived as safe, regardless of their actual properties.
People often rely on the first piece of information they encounter (the “anchor”) when making judgments. If a product is marketed as “chemical-free” or “100% natural”, this initial claim anchors the perception that alternative products containing “chemicals” are inherently inferior or dangerous. Results from qualitative interviews and a large-scale online survey conducted in the German-speaking region of Switzerland indicated that laypeople exhibited similarly negative affective responses to the terms “chemical substances” and “synthetic chemical substances”, while the term “natural chemical substances” was associated with a more positive affective response. Notably, respondents frequently associated the terms “chemical substances” and “synthetic chemical substances” with risk-laden concepts such as poison, death, and danger, while only a small minority of them associated “chemical substances” with benefits [9].
Chemophobia is often exacerbated by the fear of the unknown. When individuals lack knowledge about the science of chemistry, they are more likely to default to fear-based judgments about chemicals. This phenomenon is closely related to what psychologists call neophobia, or the fear of new or unfamiliar things. Chemicals with unfamiliar names or uses are more likely to be feared, even when scientific evidence demonstrates their safety. Conversely, familiar substances, even if harmful, tend to evoke less fear. For example, alcohol and caffeine are widely consumed despite their known health risks, while artificial sweeteners like aspartame are often avoided but have not been linked conclusively to any specific health problems, other than for people with phenylketonuria (PKU) [33,34,35].
Chemophobia is also shaped by cultural factors, which amplify the psychological tendencies described above. In many societies, the term “chemical” has become synonymous with pollution, contamination, and harm. Cultural narratives, such as those promoted by environmental advocacy groups or anti-GMO campaigns, reinforce these associations by framing chemicals as unnatural intrusions into an otherwise “pure” environment [36].
Social media further amplifies these fears by creating echo chambers where misinformation about chemicals is widely shared and rarely challenged. Viral posts about the dangers of vaccines, food additives, or cleaning products often appeal to emotions rather than evidence, making them more persuasive and memorable than nuanced scientific explanations.
Finally, chemophobia is influenced by moral judgments and emotional reactions. People often perceive natural substances as morally superior to synthetic ones, even when the latter are objectively safer or more effective. This moralization of naturalness is deeply rooted in cultural and philosophical traditions that equate “nature” with purity and “technology” with corruption [30].
Emotional reactions, such as disgust, also play a role in shaping attitudes toward chemicals. For example, the idea of consuming “synthetic” ingredients or genetically modified foods can evoke feelings of contamination or impurity, even when there is no rational basis for such reactions. For example, the results of 562 surveys conducted among Spanish wine consumers indicated a strong preference for wines without added synthetic sulfites [37].
These emotional responses are powerful drivers of behavior and are often resistant to scientific evidence or logical arguments.

2.3. The Role of Media and Marketing

Media sensationalism has played a significant role in perpetuating chemophobia. News coverage often emphasizes chemical-related health risks without providing context about dosage, exposure, or regulatory safeguards. For example, headlines about pesticide residues in food rarely clarify that the detected levels are well below safety thresholds [15]. Similarly, food advertising exploits chemophobia by promoting “chemical-free” or “100% natural” products, creating an unrealistic standard that stigmatizes synthetic additives and preservatives.

3. Chemophobia in Food Advertising

The influence of chemophobia is perhaps most visible in the food industry, where advertising campaigns frequently exploit consumer fears to market products as safer, healthier, or more “natural”. Terms like “chemical-free”, “100% natural”, and “no artificial ingredients” are widely used, despite their lack of scientific rigor and meaning. These marketing strategies capitalize on the public’s misconceptions about chemistry and reinforce the narrative that “chemicals” are inherently harmful, and that “natural” products are inherently better.
This section examines how food advertising perpetuates chemophobia, with a focus on the recent Portuguese advertisement campaign by Pingo Doce, a prominent Portuguese supermarket chain. This example highlights how marketing messages shape consumer perceptions and decisions, often at the expense of scientific accuracy.

3.1. The Role of Fear in Food Advertising

The food industry frequently leverages fear-based marketing to appeal to consumers’ emotions. Chemophobia is particularly useful in this context because it aligns with pre-existing biases and anxieties about synthetic substances. By associating their products with purity and naturalness, companies create a competitive advantage over alternatives perceived as artificial or synthetic. However, this approach also stigmatizes safe and scientifically approved additives, preservatives, and processes that are essential for food safety, quality, and accessibility.
Marketing messages that exploit chemophobia often rely on the following strategies: (1) demonizing “Artificial” ingredients: advertising often highlights the absence of synthetic additives like artificial colors, flavors, or preservatives, implying that these are harmful; (2) promoting “Natural” products: by emphasizing that their products are “natural”, companies exploit the public’s naturalness bias, even though “natural” has no standardized or scientific definition; (3) using ambiguous language: terms like “chemical-free” or “100% natural” sound reassuring but are scientifically misleading, as all substances are made of chemicals.

3.2. Pingo Doce’s Advertisement Campaign

A striking example of chemophobia-driven food advertising is the 2024 campaign by Pingo Doce, one of Portugal’s largest supermarket chains. The TV advertisement features a conversational scenario that appeals directly to common chemophobic sentiments (Figure 2).
The TV commercial implies that Pingo Doce’s products are superior because they lack “chemicals”, a term that the ad equates with harmful artificial additives like flavor enhancers and colorants. By positioning their products as free from synthetic substances, Pingo Doce aligns itself with consumer fears and reinforces chemophobia.

3.3. Analyzing the “Pingo Doce” Campaign

The central claim of the advertisement—Pingo Doce’s products being “free from chemicals”—is scientifically inaccurate and perpetuates misunderstanding. Every food product, whether processed or raw, contains chemicals because all matter is composed of chemicals. For example, (1) water (H2O), a fundamental ingredient in yogurt, is a chemical; (2) lactose, the natural sugar in milk, is a chemical compound; (3) even the natural flavor compounds in fruits, like limonene in citrus, are chemicals.
By equating “chemicals” with harmful artificial substances, the ad exploits the public’s misunderstanding of the term while failing to educate consumers about the nuances of food chemistry.
The campaign taps into the “natural fallacy”: the belief that natural substances are inherently good while synthetic substances are harmful. This false dichotomy ignores the reality that many natural substances can be toxic (e.g., cyanide in almonds or botulinum toxin), while synthetic compounds can be safe and beneficial. For example, ascorbic acid (vitamin C), often added to preserve food, is chemically identical whether it is derived from natural sources or synthesized in a laboratory.
The ad’s focus on the absence of “artificial colorants and flavor enhancers” implies that these additives are unnecessary or unsafe, ignoring their role in improving taste, shelf life, and appearance while meeting rigorous safety standards set by food regulatory bodies.
The conversational tone of the advertisement makes it relatable and reinforces a sense of shared mistrust of “chemicals”. This emotional appeal is highly effective in influencing consumer behavior, as it validates existing fears and provides a simple solution: buy Pingo Doce products to avoid harmful “chemicals”. However, this approach prioritizes marketing goals over consumer education, leaving viewers with a skewed understanding of food safety and chemistry.
It is important to notice that the sentiments and level of chemophobia vary from country to country and depend strongly on its representation in the mass media, educational system, and other specific features of a certain country. For instance, the levels of chemophobia are higher in France, Italy, and Poland compared to Switzerland, Austria, Germany, Sweden, and the UK [38].

3.4. The Broader Implications of Fear-Based Marketing

The Pingo Doce advertisement exemplifies a prevalent trend in food marketing that leverages chemophobia. While such strategies may temporarily boost sales, they have broader implications for public understanding, consumer behavior, and the food industry.
By portraying chemicals as inherently harmful, these campaigns can erode trust in scientific and regulatory bodies responsible for ensuring food safety. This skepticism may lead consumers to question the credibility of food safety standards and avoid scientifically validated products out of fear. A study conducted by Saleh and co-workers, in 2020, with 448 participants, found that providing consumers with basic toxicological knowledge can reduce chemophobia, suggesting that misinformation contributes to public distrust [39]. Empirical evidence of the study suggests that presenting simplified and accessible information about basic toxicological principles appears to be an effective way to educate the public. In contrast, using only emotional appeals that highlight the societal or personal benefits of chemicals may be insufficient to counteract the stigma. Integrating toxicology education into school curricula or sharing it through trusted scientists and experts may be a more impactful approach to reducing chemophobia.
Fear-based marketing often stigmatizes safe and beneficial synthetic additives, such as preservatives that prevent spoilage and foodborne illnesses. This can drive consumer demand for “clean-label” products, which may lack the safety and quality benefits provided by these additives. Senapathy [40] discussed how marketers exploited chemical fears for profit, leading to misconceptions about synthetic additives.
Campaigns like Pingo Doce’s contribute to widespread anxiety about food choices, making it difficult for consumers to distinguish between genuine risks and baseless fears. This confusion often results in irrational decision-making, such as avoiding processed foods entirely or paying premium prices for “natural” products. The Financial Times (2024) highlighted how ultra-processed and fast food advertising can mislead consumers, emphasizing the need for honest food branding.
Chemophobia-driven marketing can also create barriers to the adoption of new technologies in food production, such as genetically modified organisms (GMOs) or lab-grown meat, which have the potential to address global food security challenges but are often vilified as “unnatural”. Addressing chemophobia through informational approaches has been shown to reduce resistance to such innovations [39].
In summary, while fear-based marketing strategies like those employed by Pingo Doce may achieve short-term commercial objectives, they can undermine public trust in science, stigmatize beneficial food additives, increase consumer anxiety, and hinder technological advancements in the food industry.
To address the issue of chemophobia in food advertising, a multipronged approach is needed at the levels of consumer education, regulatory oversight, industry accountability, and public awareness campaigns. Educators and scientists must work to improve public understanding of chemistry, emphasizing that “natural” and “synthetic” are not synonymous with “safe” and “dangerous”. Governments should establish stricter guidelines for food labeling and advertising to prevent misleading claims such as “chemical-free” or “100% natural”. Also, food companies must adopt ethical marketing practices that prioritize transparency and factual accuracy over fear-based messaging. Initiatives like James Kennedy’s “All-Natural Banana” poster (Figure 3), which humorously lists the “chemical” ingredients in a banana, can help dispel myths about chemicals and encourage critical thinking among consumers.

4. Combating Chemophobia: A Multidisciplinary Approach

Chemistry has significantly contributed to human and economic progress, yet many consumers in Europe misunderstand the role and safety of synthetic chemicals. This lack of understanding arises from limited knowledge about how products are made and a reliance on mental shortcuts, or heuristics, when evaluating chemicals’ risks and benefits. A survey conducted by Siegrist and Bearth [42] in eight European countries, with 5631 participants with roughly 700 from each country, revealed the widespread presence of irrational fears about chemicals among the public in these countries has led many respondents to express an unrealistic wish to live in a world entirely free of chemical substances (Figure 4).
There is clear evidence indicating that adequate knowledge plays a crucial role in reducing chemophobia.
The data shown in Figure 5 reveal that only a small fraction of European consumers could correctly answer basic chemistry-related questions. In our view, this highlights an urgent need for action. Enhancing scientific literacy by improving science education at all levels and creating innovative informational campaigns to inform the public should be prioritized. The widespread fear of chemicals not only risks leading to suboptimal policy decisions but could also hinder scientific and technological innovation.
Across the surveys across eight European countries, a negative association was observed between toxicological knowledge and chemophobia, indicating that individuals with a greater understanding of toxicological principles tend to exhibit lower levels of chemophobia. In contrast, health concerns demonstrated a positive correlation.
Notably, in German-speaking countries and France, chemophobia was inversely related to trust in public authorities, suggesting that greater institutional trust may mitigate chemophobic attitudes. In Switzerland, Austria, Germany, and Poland, chemophobia also correlated positively with age, indicating that older individuals tend to express greater chemophobic concerns. Moreover, higher education was generally associated with lower levels of chemophobia across all countries, except Italy [38].
Chemophobia and the knowledge of basic toxicological principles was also tested with consumers from South Korea (N = 1019) [43], and the average level of chemophobia in this sample was comparable to the mean levels of chemophobia in European countries [38]. This suggests that chemophobia might be a global phenomenon that can be found in humans in different cultural contexts. Similarly, general knowledge about toxicological principles appears broadly comparable across regions, despite some variation in specific response patterns reflecting differing perceptions of natural versus synthetic chemicals.
For instance, the awareness that both synthetic and natural chemical substances can pose carcinogenic risks was more pronounced among European consumers compared to their South Korean counterparts.
Furthermore, it was observed that providing toxicological information at a single point in time decreased risk perception and acceptance, though it may not fully reshape consumers’ long-term views and preferences. This suggests that a larger intervention such as school-based education or interactive information may be required to achieve more meaningful changes in public perceptions and reduce unwarranted fears associated with chemical substances in consumer products.
Globally, these findings from European and South Korean consumers underscore the critical need for public education on fundamental toxicological principles as a strategy to combat chemophobia. However, it is equally important to consider other influential factors, such as underlying attitudes and the level of trust in information sources, when designing effective communication strategies.
Educating and informing consumers about toxicological principles and the risk assessment of chemical substances could help build trust in regulatory authorities and reduce levels of chemophobia.
Addressing chemophobia requires a coordinated effort involving educators, scientists, journalists, lawmakers, and public engagement initiatives. Each stakeholder group has a unique role to play in promoting scientific literacy and countering misinformation.

4.1. Educators

Educators play a pivotal role in addressing chemophobia by fostering scientific literacy and promoting a balanced understanding of chemicals and their role in everyday life. Schools and universities serve as ideal environments for introducing students to fundamental concepts such as the relationship between chemical structure and function, the principle of dosage and toxicity, and the distinctions between natural and synthetic substances. By integrating these concepts into curricula, educators can help students appreciate the critical role chemistry plays in fields such as healthcare, food production, and environmental sustainability [44].
Chemistry education should focus on highlighting the practical, real-world applications of chemical principles. For instance, discussing the chemical composition of everyday items like cleaning products, cosmetics, and food additives can help students understand the role and importance of chemicals in their daily lives. One illustrative example could involve comparing a weight-loss drug advertisement claiming that the product “contains no chemical additives or elements, making it highly beneficial for health”, with the reality that a “healthy body” itself contains over 60 chemical elements from the periodic table. In 2002, American scientists Robert Sterner and James Elser calculated an empirical molecular formula representing an average person at birth [45]. While not a literal chemical formula, this ratio represents the composition of the human body, encompassing various organic and mineral compounds, as shown in Figure 6.
Additionally, connecting chemistry to societal issues, such as climate change or green energy solutions, can further enhance relevance and engagement [46].
Hands-on experiments are an effective way to counter chemophobia, as they allow students to interact directly with chemicals and observe their properties and behaviors in a controlled setting. For instance, students can analyze the chemical makeup of fruits or common beverages to understand that “natural” products are also composed of chemicals.
Simple, safe experiments, such as studying the effects of different concentrations of substances like salt or caffeine on plants or microorganisms, illustrate the concept of dosage and its importance in determining toxicity.
Activities such as making soap (saponification) or extracting essential oils highlight the practical applications of chemical processes [47].
Science outreach programs have proven to be effective in reducing chemophobic perceptions. Outreach activities, such as chemistry demonstrations in public spaces or partnerships with local communities, provide opportunities to engage students and the general public. These programs often include experiments that showcase the “wow factor” of chemistry, such as color changes, reactions producing gas, or the creation of non-Newtonian fluids, which can captivate interest while conveying important concepts [44].
Educators should create a classroom environment that encourages open dialogue about students’ misconceptions and fears regarding chemicals. Addressing questions such as “Are synthetic chemicals always harmful?” or “What does ‘chemical-free’ really mean?” can help demystify common myths. Critical thinking exercises, such as evaluating marketing claims or analyzing media reports about chemicals, can also sharpen students’ abilities to distinguish between scientific facts and sensationalism.
One well-known topic is an exercise that is a joke, which persists on websites like http://bandhmo.org (Figure 7), and has come up a number of other times, in efforts to encourage scientific literacy, common sense, and the value of being skeptical in questioning alleged information. Dihydrogen monoxide, as the prank website’s URL shows, is sometimes abbreviated as DHMO.
Addressing chemophobia effectively involves a range of impactful teaching strategies, including real-world problem solving, inquiry-based practical exercises, interactive games, reflective writing exercises, scaffolded peer feedback, guided critique, and pre- and post-learning quizzes [48].
The use of modern technologies, such as augmented reality (AR) and virtual simulations, offers innovative ways to teach chemistry and make it more accessible. For example, (1) virtual labs allow students to safely explore reactions with hazardous substances, reducing fear while ensuring safety; (2) augmented reality (AR) applications can visualize molecules, chemical reactions, or processes like photosynthesis, making abstract concepts tangible [49].
Educators must also be equipped with up-to-date knowledge and resources to effectively teach chemistry. Professional development programs that focus on the latest advancements in food chemistry and effective teaching methodologies can empower teachers to present complex topics in an approachable and engaging manner. Collaboration with local scientists or organizations can also provide valuable support.
By implementing these strategies, educators can play a transformative role in countering chemophobia, fostering a generation of students who are informed, confident, and appreciative of the critical role of chemistry in shaping the world.
In 2022, Chalupa and Nesměrák published an article that introduced the concept of the “communication success dimension” as a novel communication strategy and applied it to the example of the renowned author Marcel Proust. They viewed Marcel Proust and his novel In Search of Lost Time as a unique opportunity for students and cultural elites to engage with chemistry in a way that aligns with their level of understanding. By highlighting Proust’s positive appreciation of chemistry and the abundant chemical references in his work, they presented chemistry in a surprising and unconventional light, challenging the traditionally negative perceptions of the field. This approach offers a pathway to move beyond superficial misunderstandings or ignorance often associated with chemophobia. As Proust himself writes in In Search of Lost Time: “It is the chemistry of Time that is at work upon society” [22].

4.2. Scientists

Scientists play a vital role in combating chemophobia, the irrational fear of chemicals, which is often driven by misinformation and amplified by fear-based narratives in the media and online platforms. Scientists have a responsibility not only to generate new knowledge but also to communicate it effectively to the public, bridging the gap between scientific expertise and lay understanding. To achieve this, scientists must engage actively with the public, employ clear communication strategies, and work to build trust, all while addressing the root causes of chemophobia [2].
Recently, Chalupa and Nesměrák [50] defended the idea of artificial intelligence (AI) as a possible solution in the forthcoming clash of narratives. For decades, AI has been quietly used in chemistry in areas such as data management, synthesis design, and toxicology. However, the recent rise of accessible and user-friendly AI tools presents chemists with both an exciting opportunity and a challenge to enhance the way chemistry is communicated and its role in society. While generative AI has faced criticism, it holds significant potential as a neutral tool for effectively conveying chemical knowledge across all levels of society. Moreover, AI can help disseminate scientifically accurate perspectives on chemistry to the public and contribute to the broader popularization of science. By doing so, it enables nearly any scientist to actively engage in science communication, potentially reducing public fears of chemistry, often referred to as chemophobia. However, leveraging AI in this way requires scientists, particularly chemists, to commit to ongoing learning and skill development. They must act as gatekeepers, ensuring the accuracy, relevance, and appropriateness of AI-generated content.
Generative AI also democratizes communication, making it essential to tailor messages to the preferences, educational backgrounds, and demographics of diverse audiences. This technology empowers not only those who craft the prompts but also those who receive and interact with the resulting information. Importantly, generative AI shifts the focus of communication to the public, rather than scientists, and this shift must be embraced to effectively use AI for outreach, education, and community engagement.
The increasing use of generative AI and the growing volume of AI-generated content may lead to a variety of competing narratives. Surprisingly, this could result in a “new Enlightenment”, driven by widespread access to information and scientific ideas. Regardless of the outcome, chemists are uniquely positioned to contribute to this transformation, given their deep understanding of the fundamental principles of matter and their ability to bridge the gap between science and art [50].
Actionable steps may include the integration of AI literacy into science and communication curricula at the secondary school level, and the development of interdisciplinary modules that combine data science, ethics, and communication to prepare students for the challenges of AI-driven science communication. However, to responsibly integrate AI into science communication, it is crucial to establish rigorous guidelines that emphasize accuracy, transparency, and inclusivity. This includes the ongoing evaluation of AI-generated content, investment in diverse training datasets, and active efforts to involve human oversight, namely chemists, in critical areas such as synthesis design, additives, natural and synthetic substances, and toxicology.
Kennedy (2018) [2] stressed that public engagement is fundamental in addressing chemophobia. Misconceptions about chemicals, often fueled by alarmist media coverage [51] and pseudoscientific claims [52], can lead to widespread fear and poor decision-making. Scientists can help counteract these trends by participating in community outreach initiatives, such as public lectures, workshops, or science fairs, where they can interact directly with audiences and provide accurate, evidence-based information. Studies have shown that such interactions can significantly improve public trust in science [53].
Effective communication is another cornerstone of scientists’ efforts to combat chemophobia. The use of overly technical language or scientific jargon can alienate non-expert audiences, exacerbating misunderstandings. Instead, scientists should adopt clear and relatable communication techniques, using analogies, metaphors, and storytelling to make complex concepts more accessible [54]. For instance, explaining that “a chemical-free product is impossible, as everything around us is made of chemicals” is a simple yet impactful way to challenge common misconceptions. Based on an analysis of the causes and consequences of chemophobia and the results of communication studies, Chalupa and Nesměrák [55] proposed a new approach (5E-principle) to improve communication between chemists and the general public. The 5E-principle—educate, emotionally, engage, entertain, and energize—provides a possible answer to the communication challenges with the general public and a useful tool for suppressing chemophobia.
Additionally, Kennedy emphasized the importance of visual aids, such as infographics and videos, which can make scientific information more engaging and easier to digest [56]. Leveraging these tools can help demystify the terminology and concepts associated with chemicals, reducing the fear that often stems from a lack of understanding.
Social media provides scientists with an unprecedented opportunity to reach a wide and diverse audience. Kennedy (2018) [2] highlighted the potential of platforms like Twitter, Facebook, and Instagram to disseminate evidence-based information and counteract the spread of misinformation. Research has shown that social media can influence public attitudes toward science, particularly when experts engage in dialogue rather than one-way communication [57]. By addressing viral myths, sharing accessible articles, and engaging in respectful discussions, scientists can play a key role in reshaping public perceptions of chemicals.
Trust is a critical factor in reducing chemophobia. Public skepticism toward chemicals is often rooted in a broader mistrust of institutions, including the scientific community. To build trust, scientists must be transparent about their work, openly discussing the risks and benefits of chemicals while acknowledging uncertainties. This approach aligns with the findings from [58], who argued that transparency and inclusiveness are essential for establishing credibility in risk communication.
Scientists can also collaborate with interdisciplinary teams, including psychologists and sociologists, to better understand the emotional and cultural factors driving chemophobia. Addressing these underlying fears requires not only scientific facts but also empathy and an understanding of public values [36].

4.3. Journalists

Journalists have a critical role in combating chemophobia by ensuring accurate and responsible reporting on topics related to chemicals. Chemophobia, often perpetuated by fear-based narratives and sensationalist media coverage, thrives on misinformation, exaggerated risks, and a lack of proper scientific context. Journalists, particularly those covering science and health-related topics, hold significant influence over public perceptions and have a responsibility to provide clear, balanced, and evidence-based information.
Responsible journalism is essential to counteract chemophobia, as media is often a primary source of scientific information for the public. Sensationalist headlines, designed to capture attention, can mislead readers by exaggerating risks or omitting critical context. For instance, studies have shown that media reports frequently emphasize the dangers of synthetic chemicals, while neglecting to explain their benefits or provide comparisons with naturally occurring chemicals [59]. Such reporting reinforces the false dichotomy of “natural equals safe, synthetic equals harmful”, a misconception central to chemophobia.
Journalists must prioritize accuracy by consulting credible scientific sources, cross-referencing data, and avoiding the temptation to oversimplify complex topics. This includes providing context, such as explaining dose–response relationships, the difference between hazard and risk, and the regulatory measures in place to ensure chemical safety. For example, communicating that a chemical is classified as “toxic” only under certain exposure conditions can help dispel undue fears.
Collaboration between journalists and scientists to ensure that media coverage reflects scientific consensus is very important. Journalists often face challenges in interpreting technical studies, and input from scientists can help clarify findings and avoid misrepresentation. Initiatives such as science media centers or journalist-training programs on scientific literacy can facilitate this collaboration, improving the quality of science reporting.
Moreover, scientists can assist journalists by providing clear, concise, and accessible explanations of their research, as well as by proactively addressing misconceptions. This partnership benefits both parties: scientists gain a platform to disseminate their findings, while journalists receive reliable information to produce accurate stories.
Journalists must avoid perpetuating fear-based narratives, which often emerge from an overemphasis on anecdotal evidence or poorly conducted studies. Research has shown that dramatic, emotionally charged stories are more likely to be shared and remembered, but they can distort public understanding of risk. To combat this, journalists should critically evaluate the quality of their sources, distinguish between preliminary findings and established science, and emphasize evidence-based conclusions.
Responsible journalism also involves correcting misinformation and addressing public fears directly. For example, if a viral story inaccurately portrays a chemical as dangerous, journalists have a duty to investigate and publish corrective pieces that provide accurate information and context.
Finally, Kennedy (2018) [2] suggested that journalists can play a role in promoting media literacy among their audiences. By explaining how scientific studies are conducted, reported, and reviewed, journalists can empower readers to critically evaluate the information they consume. This includes educating the public on the hallmarks of reliable scientific reporting, such as peer review, sample size considerations, and conflict-of-interest disclosures [59].
Thus, journalists are on the front lines of the battle against chemophobia. By prioritizing accuracy, providing context, collaborating with scientists, and avoiding fear-based narratives, journalists can foster a more informed public discourse on chemicals. Furthermore, by promoting media literacy and engaging in corrective reporting, journalists can help dispel myths and encourage rational decision-making about chemicals in everyday life. Responsible journalism, to help people critically evaluate information about chemicals and their risks, is not just a tool for combating chemophobia; it is a cornerstone of a scientifically literate and informed society.

4.4. Lawmakers

Kennedy (2018) [2] underscored the pivotal role of lawmakers in addressing chemophobia, not only by implementing policy reforms but also by fostering transparency and accountability within regulatory frameworks. Chemophobia is often perpetuated by misleading marketing practices, vague or deceptive labeling, and inadequate regulation, which together exploit consumer fears and promote misconceptions about chemicals. Lawmakers, Kennedy argued, have a responsibility to enact and enforce policies that protect consumers, encourage evidence-based decision-making, and counteract the spread of misinformation.
One of the primary recommendations is the prohibition of misleading marketing terms such as “chemical-free” which falsely imply that a product contains no chemicals. This term is scientifically inaccurate, as everything—natural or synthetic—is composed of chemicals [2]. Allowing such language to persist not only perpetuates chemophobia but also exploits consumers’ limited understanding of chemistry. By banning the use of such terms in advertising, lawmakers can help reduce the stigma associated with chemicals and promote a more scientifically accurate public discourse.
It is necessary to establish clear, standardized definitions for labels like “natural” and “organic”, which are frequently used in marketing but often lack consistent legal or scientific definitions. For example, products labeled “natural” may still contain synthetic additives or be processed in ways that undermine the term’s perceived meaning. By defining these terms clearly and ensuring that they align with scientific principles, lawmakers can protect consumers from deceptive practices and promote greater transparency in product labeling.
In addition to addressing marketing practices, it is necessary to strengthen regulatory frameworks to ensure that consumer protection laws reflect the latest scientific evidence. Robust regulations can prevent companies from exploiting chemophobia by marketing products with unfounded claims of safety or efficacy.
Strengthening regulatory frameworks also involves improving public access to reliable information about chemicals and their safety. Lawmakers can mandate the inclusion of clear, evidence-based information on product labels, such as specifying the chemical composition and intended use of products. This approach not only combats misinformation but also empowers consumers to make informed decisions based on scientific evidence [60].
Transparency is a cornerstone for combating chemophobia through legislative action. Lawmakers should require companies to disclose the sources of their ingredients, the processes used in manufacturing, and the scientific basis for any safety claims. This level of transparency can foster trust between consumers and manufacturers while reducing the influence of fear-based marketing tactics.
Evidence-based policymaking to address chemophobia involves consulting with scientists, regulatory experts, and industry stakeholders to ensure that laws and regulations are informed by the best-available scientific data. For example, policies aimed at regulating chemical exposure should take into account dose–response relationships, risk–benefit analyses, and existing safety measures. By grounding policies in science, lawmakers can avoid unnecessary restrictions on chemicals that pose minimal risk, while focusing regulatory efforts on substances with well-documented hazards.
Finally, lawmakers have a role to play in public education. Policies that fund and promote science education initiatives, public awareness campaigns, and community outreach programs can help dispel myths about chemicals and foster a more nuanced understanding of their role in society [61]. For example, lawmakers could support programs that teach consumers to critically evaluate product labels and marketing claims, thereby reducing susceptibility to chemophobia-driven marketing.
Furthermore, by supporting public education initiatives, lawmakers can address the root causes of chemophobia, empowering individuals to make rational and informed decisions about chemicals in their everyday lives.
Concrete steps proposed by [50] include implementing regulations that protect public health and the environment, while also promoting innovation and economic growth. These steps emphasize the importance of ensuring that regulations are grounded in sound science and comprehensive risk assessments.

4.5. Public Engagement

Public engagement is very important in combating chemophobia, which is often driven by widespread misinformation and fear-based narratives about chemicals. Public engagement initiatives can play a transformative role in fostering a more nuanced understanding of chemistry and promoting rational decision-making about chemical-related risks. By leveraging creative campaigns, social media, documentaries, and community events, public outreach can address misconceptions, challenge fear-based narratives, and encourage a more balanced perspective on chemicals.
Public campaigns that illustrate the ubiquity of chemicals and the flaws in the “chemical-free” narrative are very important. One referenced example is Kennedy’s “All-Natural Banana” poster (Figure 3), which lists the chemical components of a banana—such as ascorbic acid (vitamin C), glucose, and potassium chloride—in a way that mimics ingredient lists on packaged foods. This campaign effectively demonstrates that all substances, including those in natural foods, are made up of chemicals. By presenting this information in a relatable and visually engaging format, such campaigns help to demystify the term “chemical” and challenge the assumption that chemicals are inherently harmful.
Public campaigns can also address other misconceptions, such as the belief that “natural” products are always safer than synthetic ones or that exposure to any amount of a toxic substance is dangerous. For example, the concept of “the dose makes the poison”, popularized by Paracelsus, can be conveyed through infographics, videos, or interactive exhibits to illustrate that risk depends on exposure levels rather than the mere presence of a chemical [36].
Social media platforms provide an effective and far-reaching tool for engaging the public on topics related to chemistry. Scientists, educators, and communicators can use platforms like Twitter, Instagram, and YouTube to share evidence-based information, debunk myths, and interact directly with audiences. For example, hashtags like #ChemistryEverywhere or #ScienceNotScare can be used to amplify messages that counter chemophobia.
Studies have shown that social media can significantly influence public perceptions of science, particularly when messages are tailored to resonate with the values and concerns of different audiences [57]. By creating relatable and engaging content, such as short videos explaining the science behind everyday products or memes that challenge misconceptions, social media campaigns can reach diverse demographics and foster a more informed public discourse.
Documentaries and other multimedia projects can play a powerful role in combating chemophobia by providing in-depth, engaging, and visually compelling explorations of chemistry-related topics. Documentaries focusing on the history of chemistry, the benefits of synthetic chemicals, and the science of risk assessment can help audiences understand the complexities of chemical use in society. Films like The Story of Stuff [62] have demonstrated the potential of multimedia to spark public conversations about environmental and health-related issues.
In addition to documentaries, shorter video formats designed for online platforms can be particularly effective for reaching younger audiences. One example is The Chemistry of Things, based on an original idea by Paulo Ribeiro Claro (University of Aveiro) and developed by the Science Office and Duvideo Filmes at http://www.aquimicadascoisas.org. The Chemistry of Things is available on multiple platforms and formats as a series of 26 episodes for television broadcasted on Portuguese National Television and SIC K, official website, Facebook, Twitter, and other social networks. This is a great example of how collaborations between scientists, educators, and filmmakers can ensure that these projects are both scientifically accurate and engaging.
Community events, such as science fairs, public lectures, and hands-on workshops, provide opportunities for direct interaction between scientists and the public. Such events are important in demystifying chemistry and building trust. For example, interactive exhibits that allow participants to conduct simple experiments, such as testing pH levels or extracting DNA from fruit, can make chemistry more accessible and relatable.
Public engagement initiatives can also address chemophobia by partnering with schools, museums, and community organizations to integrate chemistry education into broader public programs. Such partnerships can help reach audiences who may not otherwise seek out science-related content, fostering a culture of curiosity and critical thinking.
To ensure the effectiveness of public engagement efforts, it is important to evaluate their impact on public attitudes and understanding. Surveys, focus groups, and social media analytics can be used to assess changes in perceptions of chemicals and identify areas for improvement. Research has shown that well-designed public engagement initiatives can significantly improve science literacy and reduce misinformation [53].

5. Conclusions

Chemophobia continues to negatively impact both chemistry and human life, especially when it leads to poor decisions driven by a lack of understanding of chemistry and fear of chemicals. Therefore, efforts should be made to address and eliminate chemophobia, which presents a significant challenge to the modern world, shaping consumer behavior, influencing regulatory decisions, and creating barriers to scientific innovation. While fear of chemicals is often rooted in legitimate concerns—such as historical incidents of industrial pollution or the misuse of synthetic substances—it has evolved into a broader cultural phenomenon that frequently misrepresents the role of chemistry in everyday life. The perception that chemicals are inherently harmful and that “natural” products are always safer is not only scientifically inaccurate but also detrimental to public health and progress.
The consequences of chemophobia are particularly evident in the food industry, where consumer demands for “chemical-free” or “100% natural” products drive the marketing strategies that mislead the public. This has led to a stigmatization of synthetic additives and preservatives, even when these compounds are scientifically proven to be safe and beneficial. Moreover, this fear-driven market dynamic can discourage innovation, as companies may avoid the use of new chemical technologies due to potential consumer backlash.
Addressing chemophobia requires a coordinated effort across multiple sectors of society. Education is the cornerstone of this effort, as it provides the foundation for scientific literacy and critical thinking. By teaching concepts such as dosage, chemical processes, and the neutrality of chemicals, educators can demystify the subject and help students develop a balanced understanding of chemistry. Scientists, too, have a crucial role to play in public engagement, using accessible language and relatable examples to communicate the complexities of chemical science.
Journalists and media professionals must also take responsibility for their role in shaping public discourse. By avoiding sensationalism and consulting experts for context, they can present a more balanced view of chemical-related issues. At the same time, policymakers must enact regulations to prevent misleading advertising and labeling practices, such as the use of terms like “chemical-free” that exploit consumer fears.
Ultimately, public engagement is essential to combating chemophobia. Campaigns that highlight the ubiquity and importance of chemicals in our lives can help shift perceptions and reduce irrational fears. High-profile advocates, including scientists and educators, can serve as trusted voices in this effort, promoting a culture of curiosity and evidence-based understanding.
A multifaceted approach to reversing chemophobia could include fostering partnerships among the industry, academia, government, and non-profit organizations to address the issue collaboratively.
Chemicals are neither inherently good nor bad: “Chemicals are like people—some are good, some are bad, and most are in between” as mentioned by T. Whitcombe [63]. Chemicals are tools that must be understood and used responsibly. By fostering a more informed and nuanced perspective on chemistry, society can overcome the challenges posed by chemophobia and embrace the many benefits that the chemical sciences have to offer. This transformation will not only improve public understanding but also pave the way for greater trust in science and innovation, ensuring that chemistry continues to contribute to the betterment of human life.

Author Contributions

Conceptualization, M.J.B. and A.M.d.S.; writing—original draft preparation, M.J.B. and A.M.d.S.; writing—review and editing, M.J.B. and A.M.d.S. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Data Availability Statement

No research data were gathered for this work.

Acknowledgments

During the preparation of this manuscript, the authors used https://openai.com/ for the purposes of improving its readability and language. The authors have reviewed and edited the output and take full responsibility for the content of this publication.

Conflicts of Interest

The authors declare no conflicts of interest.

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Figure 1. Timeline of some events that could have led to the emergence of chemophobia published by Rollini et al. (2022) [7].
Figure 1. Timeline of some events that could have led to the emergence of chemophobia published by Rollini et al. (2022) [7].
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Figure 2. Scene summary of the “Pingo Doce” advertising.
Figure 2. Scene summary of the “Pingo Doce” advertising.
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Figure 3. List of the “chemical” ingredients in a banana [41].
Figure 3. List of the “chemical” ingredients in a banana [41].
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Figure 4. Responses to three questions designed to provide a measure of chemophobia. Adapted from [42].
Figure 4. Responses to three questions designed to provide a measure of chemophobia. Adapted from [42].
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Figure 5. Responses to two questions designed to gauge the chemical knowledge of the consumers taking part in the survey. Adapted from [42].
Figure 5. Responses to two questions designed to gauge the chemical knowledge of the consumers taking part in the survey. Adapted from [42].
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Figure 6. Empirical molecular formula for an average person at birth.
Figure 6. Empirical molecular formula for an average person at birth.
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Figure 7. The controversy surrounding dihydrogen monoxide has been widely debated, and the goal of the http://bandhmo.org is to provide an unbiased data clearinghouse and a forum for public discussion.
Figure 7. The controversy surrounding dihydrogen monoxide has been widely debated, and the goal of the http://bandhmo.org is to provide an unbiased data clearinghouse and a forum for public discussion.
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Moreira da Silva, A.; Barroca, M.J. Addressing Chemophobia: Bridging Misconceptions in Food Chemistry. Appl. Sci. 2025, 15, 6104. https://doi.org/10.3390/app15116104

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Moreira da Silva A, Barroca MJ. Addressing Chemophobia: Bridging Misconceptions in Food Chemistry. Applied Sciences. 2025; 15(11):6104. https://doi.org/10.3390/app15116104

Chicago/Turabian Style

Moreira da Silva, Aida, and Maria João Barroca. 2025. "Addressing Chemophobia: Bridging Misconceptions in Food Chemistry" Applied Sciences 15, no. 11: 6104. https://doi.org/10.3390/app15116104

APA Style

Moreira da Silva, A., & Barroca, M. J. (2025). Addressing Chemophobia: Bridging Misconceptions in Food Chemistry. Applied Sciences, 15(11), 6104. https://doi.org/10.3390/app15116104

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