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Review

Actions and Therapeutic Potential of Madecassoside and Other Major Constituents of Centella asiatica: A Review

1
School of Postgraduate Studies, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia
2
School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia
*
Authors to whom correspondence should be addressed.
Academic Editors: Hari Prasad Devkota and Alessandra Durazzo
Appl. Sci. 2021, 11(18), 8475; https://doi.org/10.3390/app11188475
Received: 20 July 2021 / Revised: 2 September 2021 / Accepted: 4 September 2021 / Published: 13 September 2021
Centella asiatica is a popular herb well-known for its wide range of therapeutic effects and its use as a folk medicine for many years. Its therapeutic properties have been well correlated with the presence of asiaticoside, madecassoside, asiatic and madecassic acids, the pentacyclic triterpenes. The herb has been extensively known to treat skin conditions; nevertheless, several pre-clinical and clinical studies have scientifically demonstrated its effectiveness in other disorders. Among the active constituents that have been identified in Centella asiatica, madecassoside has been the subject of only a relatively small number of scientific reports. Therefore, this review, while including other major constituents of this plant, focuses on the therapeutic potential, pharmacokinetics and toxicity of madecassoside. View Full-Text
Keywords: madecassoside; Centella asiatica; asiaticoside; asiatic acid; madecassic acid madecassoside; Centella asiatica; asiaticoside; asiatic acid; madecassic acid
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MDPI and ACS Style

Tan, S.C.; Bhattamisra, S.K.; Chellappan, D.K.; Candasamy, M. Actions and Therapeutic Potential of Madecassoside and Other Major Constituents of Centella asiatica: A Review. Appl. Sci. 2021, 11, 8475. https://doi.org/10.3390/app11188475

AMA Style

Tan SC, Bhattamisra SK, Chellappan DK, Candasamy M. Actions and Therapeutic Potential of Madecassoside and Other Major Constituents of Centella asiatica: A Review. Applied Sciences. 2021; 11(18):8475. https://doi.org/10.3390/app11188475

Chicago/Turabian Style

Tan, Swee Ching, Subrat Kumar Bhattamisra, Dinesh Kumar Chellappan, and Mayuren Candasamy. 2021. "Actions and Therapeutic Potential of Madecassoside and Other Major Constituents of Centella asiatica: A Review" Applied Sciences 11, no. 18: 8475. https://doi.org/10.3390/app11188475

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