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Open AccessFeature PaperArticle

Screening of Antioxidant Potentials and Bioactive Properties of the Extracts Obtained from Two Centaurea L. Species (C. kroumirensis Coss. and C. sicula L. subsp sicula)

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UR13ES63-Chimie Appliquée et Environnement, Département de Chimie, Faculté des Sciences, Université de Monastir, Bvd de l’Environnement, Monastir 5000, Tunisie
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Laboratorio di Biochimica Marina ed Ecotossicologia, Dipartimento di Scienze della terra e del Mare DiSTeM, Università degli Studi di Palermo, Via G. Barlotta 4, 91100 Trapani, Italy
3
Laboratory of Analysis, Treatment and Valorization of Pollutants of the Environment and Products, Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia
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Istituto di Biologia Marina, Consorzio Universitario della Provincia di Trapani, Via G. Barlotta 4, 91100 Trapani, Italy
*
Author to whom correspondence should be addressed.
Appl. Sci. 2020, 10(7), 2267; https://doi.org/10.3390/app10072267 (registering DOI)
Received: 28 February 2020 / Revised: 11 March 2020 / Accepted: 18 March 2020 / Published: 26 March 2020
(This article belongs to the Special Issue Bioactive Substances: Properties, Applications and or Toxicities)
Herbal medicines, dietary supplements, or infusions with health promoting effects can note strong consumer demand. Hence, researchers and scientists have been increasingly focusing on the promotion of medicinal plants. In this respect, the present study has the evaluation of the biological properties of different extracts (hexane, chloroform, methanol, ultrasonic, essential oil, and supercritical) obtained from two Centaurea species (C. kroumirensis (Coss.) and C. sicula L. subsp sicula) as purpose. Antioxidative activities were assessed by in vitro assays including total phenolic content, free radical scavenging assay and ferric ion reducing power. Among the fourteen extracts examined, the highest total phenolic content (TPC) and antioxidant abilities were recorded in ultrasonic ethanol extracts of both Centaurea species. Additionally, these extracts exhibited a noticeable strong protective effect of the human skin fibroblast cell line (HS-68) that was exposed to oxidative stress induced by hydrogen peroxide. According to our results, the sonication with ethanol might be an ideal, rapid, and eco-friendly extraction method for obtaining a polyphenol-rich extract that exhibited high antioxidant activity. The results presented herein suggest that Centaurea species could be promoted as an antioxidant resource that could be exploited for the development of nutraceuticals or in pharmacology industry. View Full-Text
Keywords: Centaurea spp; antioxidant; phenolics; plant extract; protective effect Centaurea spp; antioxidant; phenolics; plant extract; protective effect
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MDPI and ACS Style

Dhouibi, N.; Manuguerra, S.; Arena, R.; Mahdhi, A.; Messina, C.M.; Santulli, A.; Dhaouadi, H. Screening of Antioxidant Potentials and Bioactive Properties of the Extracts Obtained from Two Centaurea L. Species (C. kroumirensis Coss. and C. sicula L. subsp sicula). Appl. Sci. 2020, 10, 2267.

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