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Open AccessFeature PaperReview

Determining the Effects of Eugenol on the Bond Strength of Resin-Based Restorative Materials to Dentin: A Meta-Analysis of the Literature

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Dental Materials Laboratory, Department of Conservative Dentistry, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre 90035-003, RS, Brazil
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Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia
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Dental Biomedical Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA
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Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain
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Departamento de Odontología, Facultad de Ciencias de la Salud, Universidad CEU-Cardenal Herrera, C/Del Pozos/n, Alfara del Patriarca, 46115 Valencia, Spain
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Department of Therapeutic Dentistry, Sechenov University of Moscow, 119435 Moscow, Russia
*
Author to whom correspondence should be addressed.
Appl. Sci. 2020, 10(3), 1070; https://doi.org/10.3390/app10031070
Received: 1 January 2020 / Revised: 24 January 2020 / Accepted: 3 February 2020 / Published: 5 February 2020
(This article belongs to the Special Issue Permanent and Long-Term Biodegradable Biomaterials)
The aim of this study was to determine whether the residual presence of eugenol in coronal dentin may compromise the bond strength of resin-based restorative materials. A search was performed on MEDLINE/Pubmed, Scopus, and by hand search for relevant papers. No restriction was applied for language and publication date. The studies selected for analysis tested specimens with reduced size (micro-shear bond strength (µSBS) and micro-tensile bond strength (µTBS)) of adhesive systems and resin-based restorative materials applied to coronary dentin “contaminated” with eugenol-based materials. The search provided 335 articles, but only 10 studies met the inclusion criteria. The pooled global analysis showed a significant influence of eugenol, as it negatively influenced the bond strength of resin-based restorations (5.79 (3.31–8.28) MPa, p < 0.00001). The subgroup analyses for conventional etch-and-rinse (p = 0.003) and self-etch (p < 0.0004) adhesive systems, as well as for µSBS (p = 0.01) and µTBS (p < 0.0001), showed a negative influence of eugenol on the bond strength. Data were statistically heterogeneous. However, it was possible to observe that eugenol could negatively affect the bonding of resin-based restorative materials to dentin. Further evidence is necessary in order to acquire more accurate information about this issue and confirm that the residual presence of eugenol in dentin compromises the bond strength of resin-based materials. View Full-Text
Keywords: eugenol; dentin; adhesive; zinc oxide–eugenol cement; dental cements; dental bonding eugenol; dentin; adhesive; zinc oxide–eugenol cement; dental cements; dental bonding
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Garcia, I.M.; Leitune, V.C.B.; Ibrahim, M.S.; Melo, M.A.S.; Faus Matoses, V.; Sauro, S.; Collares, F.M. Determining the Effects of Eugenol on the Bond Strength of Resin-Based Restorative Materials to Dentin: A Meta-Analysis of the Literature. Appl. Sci. 2020, 10, 1070.

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