Detection of Serum Allergen-Specific IgE in Atopic Dogs Tested in Northern Italy: Preliminary Study
Faculty of Veterinary Medicine, Veterinary University Hospital, University of Teramo, Piano d’Accio, 64100 Teramo, Italy
Veterinary Clinic Dr. Paolo Rosi, via Brescia 46, 25086 Rezzato (BS), Italy
Authors to whom correspondence should be addressed.
These authors contributed equally to the work.
Academic Editor: Simon L. Priestnall
Received: 31 December 2020 / Revised: 27 January 2021 / Accepted: 27 January 2021 / Published: 1 February 2021
Canine atopic dermatitis (CAD) is a genetically predisposed allergic skin disease associated to IgE-mediated hypersensitivity. Serum Allergen-Specific IgE test (SAT) is used to detect allergen-specific IgE antibodies and to set-up a specific immunotherapy. The present study aims to identify the most relevant environmental allergens in a population of atopic dogs living in Northern Italy by using SAT, due to the absence of data in this area. Out of 117 selected client-owned dogs, 69 were included in the study. A screening test was used to identify indoor and outdoor allergens positivity and a specific serum allergy test was performed to detect an extended panel of allergens. Among the 49 positives to the screening test, 53% were positive for both indoor and outdoor, 38.8% only for indoor, and 8.2% only for outdoor allergens. Mites and pollen of Rumex acetosa, and grasses were the most represented allergens. This is the first study to collect data on the frequency of specific allergens involved in CAD in Italy by using SAT. In accordance with the result of this study, specific panels for geographical areas should be considered and re-evaluated at time intervals since numerous factors affect the prevalence of IgE positivity in atopic dogs.