Case Report of a Mare Diagnosed with a Metastatic Mammary Carcinoma after the Excision of a Recurrent Intraocular Neuroepithelial Tumor
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials, Methods, and Results
2.1. Case Description and In Vivo Investigations
2.2. Post Mortem Examinations
3. Discussion
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Antibody | Features | Clone | Dilution | Localization | Tumor Positivity | Metastases Positivity | First Intraocular Mass | Second Intraocular Mass |
---|---|---|---|---|---|---|---|---|
PanCK | Dako® (Santa Clara, CA, USA) monoclonal | AE1/AE3 | 1:100 | Cytoplasm | 75% | 60% | 15–20% | 100% |
mouse anti-human | (strong) | (strong) | (strong) | (strong) | ||||
CK 14 | Novocastra® (Newcastle, UK) monoclonal | LL002 | 1:20 | Cytoplasm | negative | 10% | / | 30% |
mouse anti-human | (strong) | (strong) | ||||||
CK 5/6 | Dako® monoclonal | D5/16 B4 | 1:50 | Cytoplasm | 15% | 19% | / | 5% |
mouse anti-human | (strong) | (strong) | (strong) | |||||
p63 | GeneTex® (Irvine, CA, USA) polyclonal | N2C1 | 1:200 | Nucleus | negative | negative | / | negative |
mouse anti-human | ||||||||
Vimentin | Dako® monoclonal | V9 | 1:150 | Cytoplasm | stromal | 15–20% | 100% | |
mouse anti-vimentin | (strong) | (strong) | ||||||
Calponin | Dako® monoclonal | CALP | 1:200 | Cytoplasm | stromal | / | negative | |
mouse anti-human | ||||||||
ER | Novocastra® monoclonal | 6F11 | 1:40 | Cytoplasm | not cross-reactive | |||
mouse anti-human | ||||||||
PR | Ventana® (Tucson, AZ, USA) monoclonal rabbit anti-human | 1E2 | 1:80 | Nucleus | negative | 16% | / | negative |
(mild) | ||||||||
NSE | Dako® monoclonal | BBS/NC/VI-H14 | 1:250 | Cytoplasm | negative | 15–20% | 100% | |
mouse anti-human | (strong) | (strong) | ||||||
PNL2 | Santa Cruz Biotech® (Dallas, TX, USA) | sc-59306 | 1:100 | Cytoplasm | / | negative | / | |
monoclonal | ||||||||
mouse anti-human |
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Brocca, G.; Centelleghe, C.; Padoan, E.; Stoppini, R.; Giudice, C.; Castagnaro, M.; Zappulli, V. Case Report of a Mare Diagnosed with a Metastatic Mammary Carcinoma after the Excision of a Recurrent Intraocular Neuroepithelial Tumor. Animals 2020, 10, 2409. https://doi.org/10.3390/ani10122409
Brocca G, Centelleghe C, Padoan E, Stoppini R, Giudice C, Castagnaro M, Zappulli V. Case Report of a Mare Diagnosed with a Metastatic Mammary Carcinoma after the Excision of a Recurrent Intraocular Neuroepithelial Tumor. Animals. 2020; 10(12):2409. https://doi.org/10.3390/ani10122409
Chicago/Turabian StyleBrocca, Ginevra, Cinzia Centelleghe, Elisa Padoan, Riccardo Stoppini, Chiara Giudice, Massimo Castagnaro, and Valentina Zappulli. 2020. "Case Report of a Mare Diagnosed with a Metastatic Mammary Carcinoma after the Excision of a Recurrent Intraocular Neuroepithelial Tumor" Animals 10, no. 12: 2409. https://doi.org/10.3390/ani10122409
APA StyleBrocca, G., Centelleghe, C., Padoan, E., Stoppini, R., Giudice, C., Castagnaro, M., & Zappulli, V. (2020). Case Report of a Mare Diagnosed with a Metastatic Mammary Carcinoma after the Excision of a Recurrent Intraocular Neuroepithelial Tumor. Animals, 10(12), 2409. https://doi.org/10.3390/ani10122409