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Review

Hijacking the Host Immune Cells by Dengue Virus: Molecular Interplay of Receptors and Dengue Virus Envelope

by 1,2, 1,2,†, 1,2,† and 1,2,*
1
CSIR-Indian Institute of Chemical Biology; 4, Raja S.C. Mullick Road, Jadavpur, Kolkata 700032, West Bengal, India
2
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Microorganisms 2019, 7(9), 323; https://doi.org/10.3390/microorganisms7090323
Received: 1 July 2019 / Revised: 7 August 2019 / Accepted: 8 August 2019 / Published: 6 September 2019
(This article belongs to the Section Molecular Microbiology and Immunology)
Dengue virus (DENV) is one of the lethal pathogens in the hot climatic regions of the world and has been extensively studied to decipher its mechanism of pathogenesis and the missing links of its life cycle. With respect to the entry of DENV, multiple receptors have been recognized in different cells of the human body. However, scientists still argue whether these identified receptors are the exclusive entry mediators for the virus. Adding to the complexity, DENV has been reported to be infecting multiple organ types in its human host. Also, more than one receptor in a particular cell has been discerned to take part in mediating the ingress of DENV. In this review, we aim to discuss the different cells of the human immune system that support DENV infection and their corresponding receptors that DENV deploy to gain access to the cells. View Full-Text
Keywords: DENV; tropism; receptors; entry; immune cells DENV; tropism; receptors; entry; immune cells
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MDPI and ACS Style

Begum, F.; Das, S.; Mukherjee, D.; Ray, U. Hijacking the Host Immune Cells by Dengue Virus: Molecular Interplay of Receptors and Dengue Virus Envelope. Microorganisms 2019, 7, 323. https://doi.org/10.3390/microorganisms7090323

AMA Style

Begum F, Das S, Mukherjee D, Ray U. Hijacking the Host Immune Cells by Dengue Virus: Molecular Interplay of Receptors and Dengue Virus Envelope. Microorganisms. 2019; 7(9):323. https://doi.org/10.3390/microorganisms7090323

Chicago/Turabian Style

Begum, Feroza, Sandeepan Das, Debica Mukherjee, and Upasana Ray. 2019. "Hijacking the Host Immune Cells by Dengue Virus: Molecular Interplay of Receptors and Dengue Virus Envelope" Microorganisms 7, no. 9: 323. https://doi.org/10.3390/microorganisms7090323

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