Next Article in Journal
Transcription of IVIAT and Virulence Genes in Photobacterium damselae subsp. piscicida Infecting Solea senegalensis
Next Article in Special Issue
Thermostable Xylanase Production by Geobacillus sp. Strain DUSELR13, and Its Application in Ethanol Production with Lignocellulosic Biomass
Previous Article in Journal
Stable Isotope and Metagenomic Profiling of a Methanogenic Naphthalene-Degrading Enrichment Culture
Previous Article in Special Issue
Genome Analysis of Vallitalea guaymasensis Strain L81 Isolated from a Deep-Sea Hydrothermal Vent System
Open AccessReview

Cellulases from Thermophiles Found by Metagenomics

Grupo EXPRELA, Centro de Investigacións Científicas Avanzadas (CICA), Departamento de Bioloxía, Facultade de Ciencias, Universidade da Coruña, 15071 A Corunna, Spain
Author to whom correspondence should be addressed.
Microorganisms 2018, 6(3), 66;
Received: 21 June 2018 / Revised: 4 July 2018 / Accepted: 5 July 2018 / Published: 10 July 2018
(This article belongs to the Special Issue Thermophiles and Thermozymes)
Cellulases are a heterogeneous group of enzymes that synergistically catalyze the hydrolysis of cellulose, the major component of plant biomass. Such reaction has biotechnological applications in a broad spectrum of industries, where they can provide a more sustainable model of production. As a prerequisite for their implementation, these enzymes need to be able to operate in the conditions the industrial process requires. Thus, cellulases retrieved from extremophiles, and more specifically those of thermophiles, are likely to be more appropriate for industrial needs in which high temperatures are involved. Metagenomics, the study of genes and gene products from the whole community genomic DNA present in an environmental sample, is a powerful tool for bioprospecting in search of novel enzymes. In this review, we describe the cellulolytic systems, we summarize their biotechnological applications, and we discuss the strategies adopted in the field of metagenomics for the discovery of new cellulases, focusing on those of thermophilic microorganisms. View Full-Text
Keywords: cellulases; thermophiles; metagenomics; biotechnology cellulases; thermophiles; metagenomics; biotechnology
Show Figures

Graphical abstract

MDPI and ACS Style

Escuder-Rodríguez, J.-J.; DeCastro, M.-E.; Cerdán, M.-E.; Rodríguez-Belmonte, E.; Becerra, M.; González-Siso, M.-I. Cellulases from Thermophiles Found by Metagenomics. Microorganisms 2018, 6, 66.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

Back to TopTop