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Entomological Assessment of Onchocerca Species Transmission by Black Flies in Selected Communities in the West Region of Cameroon
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Zoonotic Implications of Onchocerca Species on Human Health

1
Instituto de Ganadería de Montaña (CSIC-Universidad de León), 24346 León, Spain
2
Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, 24071 León, Spain
3
Instituto de Salud Global de Barcelona (ISGlobal), 08036 Barcelona, Spain
4
Departmento de Ciencias Biomédicas, Facultad de Veterinaria, Universidad de León, 24071 León, Spain
*
Author to whom correspondence should be addressed.
Pathogens 2020, 9(9), 761; https://doi.org/10.3390/pathogens9090761
Received: 31 July 2020 / Revised: 10 September 2020 / Accepted: 15 September 2020 / Published: 17 September 2020
(This article belongs to the Special Issue Onchocerciasis and River Epilepsy)
The genus Onchocerca includes several species associated with ungulates as hosts, although some have been identified in canids, felids, and humans. Onchocerca species have a wide geographical distribution, and the disease they produce, onchocerciasis, is generally seen in adult individuals because of its large prepatency period. In recent years, Onchocerca species infecting animals have been found as subcutaneous nodules or invading the ocular tissues of humans; the species involved are O. lupi, O. dewittei japonica, O. jakutensis, O. gutturosa, and O. cervicalis. These findings generally involve immature adult female worms, with no evidence of being fertile. However, a few cases with fertile O. lupi, O. dewittei japonica, and O. jakutensis worms have been identified recently in humans. These are relevant because they indicate that the parasite’s life cycle was completed in the new host—humans. In this work, we discuss the establishment of zoonotic Onchocerca infections in humans, and the possibility of these infections to produce symptoms similar to human onchocerciasis, such as dermatitis, ocular damage, and epilepsy. Zoonotic onchocerciasis is thought to be an emerging human parasitic disease, with the need to take measures such as One Health Strategies, in order to identify and control new cases in humans. View Full-Text
Keywords: Onchocerca; zoonosis; animal species; clinical signs Onchocerca; zoonosis; animal species; clinical signs
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MDPI and ACS Style

Cambra-Pellejà, M.; Gandasegui, J.; Balaña-Fouce, R.; Muñoz, J.; Martínez-Valladares, M. Zoonotic Implications of Onchocerca Species on Human Health. Pathogens 2020, 9, 761. https://doi.org/10.3390/pathogens9090761

AMA Style

Cambra-Pellejà M, Gandasegui J, Balaña-Fouce R, Muñoz J, Martínez-Valladares M. Zoonotic Implications of Onchocerca Species on Human Health. Pathogens. 2020; 9(9):761. https://doi.org/10.3390/pathogens9090761

Chicago/Turabian Style

Cambra-Pellejà, Maria; Gandasegui, Javier; Balaña-Fouce, Rafael; Muñoz, José; Martínez-Valladares, María. 2020. "Zoonotic Implications of Onchocerca Species on Human Health" Pathogens 9, no. 9: 761. https://doi.org/10.3390/pathogens9090761

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