Next Article in Journal
Characterization of Salmonella Isolates from Wastewater Treatment Plant Influents to Estimate Unreported Cases and Infection Sources of Salmonellosis
Next Article in Special Issue
Human Metapneumovirus: Etiological Agent of Severe Acute Respiratory Infections in Hospitalized and Deceased Patients with a Negative Diagnosis of Influenza
Previous Article in Journal
Genotypic Comparison between Streptococcus suis Isolated from Pigs and Humans in Thailand
Open AccessReview

HMPV in Immunocompromised Patients: Frequency and Severity in Pediatric Oncology Patients

School of Medicine. Instituto Universitario de Ciencias Médicas y Humanísticas de Nayarit; Tepic 63190, Mexico
Centro de Investigación Oncológica Una Nueva Esperanza-Universidad Popular Autónoma del Estado de Puebla; Universidad Popular Autónoma del Estado de Puebla, 21 sur #1103, Barrio de Santiago, Puebla 72410, Mexico
Author to whom correspondence should be addressed.
Pathogens 2020, 9(1), 51;
Received: 3 December 2019 / Revised: 30 December 2019 / Accepted: 7 January 2020 / Published: 10 January 2020
(This article belongs to the Special Issue Human Metapneumovirus Infection)
Cancer is the first cause of death by disease in childhood globally. The most frequent types of cancers in children and adolescents are leukemias, followed by brain and central nervous system tumors and lymphomas. The recovery rate of cancer in children is around 80% in developed countries and up to 30% in developing countries. Some of the main causes of complications in children and adolescents with cancer are respiratory viral infections, mainly in bone marrow-transplanted patients. Respiratory viruses have been detected in the bronchoalveolar lavage or nasal wash specimens from cancer patients with or without respiratory illness symptoms. Human metapneumovirus (HMPV) is within the ten most common viruses that are encountered in samples from pediatric patients with underlying oncology conditions. In most of cases, HMPV is found as the only viral agent, but co-infection with other viruses or with bacterial agents has also been reported. The discrepancies between the most prevalent viral agents may be due to the different populations studied or the range of viral agents tested. Some of the cases of infection with HMPV in cancer patients have been fatal, especially in those who have received a hematopoietic stem cell transplant. This review seeks to show a general view of the participation of HMPV in respiratory illness as a complication of cancer in childhood and adolescence. View Full-Text
Keywords: pediatric cancer infections; HMPV; fatal cases in HSCT patients pediatric cancer infections; HMPV; fatal cases in HSCT patients
MDPI and ACS Style

Martinez-Rodriguez, C.; Banos-Lara, M.R. HMPV in Immunocompromised Patients: Frequency and Severity in Pediatric Oncology Patients. Pathogens 2020, 9, 51.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop