Next Article in Journal
Fighting Strategies Against Chagas’ Disease: A Review
Previous Article in Journal
Recognition, Diagnosis, and Treatment of Clostridioides difficile Enterocolitis Presenting Without Diarrhea: A Literature Review
Previous Article in Special Issue
Loop-Mediated Isothermal Amplification for the Fast Detection of Bonamia ostreae and Bonamia exitiosa in Flat Oysters
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Pathogens
Volume 14
Issue 2
10.3390/pathogens14020182
pathogens-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Analysis of Halophilic Phenotypic Variation and Cytotoxicity of Vibrio parahaemolyticus from Different Sources

by
Jingyue Gu
1,
Xin Dong
2,
Yunqian Zhou
3,
Ying Zhao
2,
Qiang Du
2,
Jia Chen
2,
Xujian Mao
2,
Fengming Wang
2 and
Bowen Tu
1,2,3,*
1
School of Public Health, Xuzhou Medical University, Xuzhou 221004, China
2
Changzhou Centre for Disease Control and Prevention, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, China
3
School of Public Health, Nanjing Medical University, Nanjing 211166, China
*
Author to whom correspondence should be addressed.
Pathogens 2025, 14(2), 182; https://doi.org/10.3390/pathogens14020182
Submission received: 3 January 2025 / Revised: 5 February 2025 / Accepted: 8 February 2025 / Published: 12 February 2025
(This article belongs to the Special Issue Aquatic Animal Pathogens: Epidemiology, Pathogenesis, Diagnosis, Preventive and Therapeutic Measures and Host–Pathogen Relationships)
Browse Figures
Review Reports Versions Notes

Abstract

Vibrio parahaemolyticus is an aquatic animal pathogen. Recently, the detection rate of V. parahaemolyticus in freshwater products has exceeded that in seafood products, and the strains isolated from freshwater products exhibit better growth conditions in low-salinity environments. This study is based on a food risk detection activity in Changzhou, Jiangsu Province, China, investigating the variation of halophilism and the virulence of two groups of strains under different salt concentrations. Under 0%, 0.5%, and 1% salt, the strains from the freshwater showed faster growth than those from the seawater. In comparison, the strains from the seawater group under 2% and 3% salt grew faster than the growing status under the foregoing low-salt concentration environment. The cytotoxicity produced by the two strains was approximately 1.4 times higher in the 0.5% and 1% salt concentration groups compared to the 3% corresponding experimental group. Under the 0%, 0.5%, and 1% salt, the cytotoxicity of strains in the freshwater group increased by nearly 20% compared to that in the seawater groups. The freshwater strains showed altered halophilism and adapted to the low-salt environment. This research will be helpful in establishing a local and global control strategy against the diseases resulting from V. parahaemolyticus.
Keywords: foodborne disease; freshwater products; aquatic animal pathogen evolution; host-pathogen interaction; virulence alteration; low-saline water foodborne disease; freshwater products; aquatic animal pathogen evolution; host-pathogen interaction; virulence alteration; low-saline water

Share and Cite

MDPI and ACS Style

Gu, J.; Dong, X.; Zhou, Y.; Zhao, Y.; Du, Q.; Chen, J.; Mao, X.; Wang, F.; Tu, B. Analysis of Halophilic Phenotypic Variation and Cytotoxicity of Vibrio parahaemolyticus from Different Sources. Pathogens 2025, 14, 182. https://doi.org/10.3390/pathogens14020182

AMA Style

Gu J, Dong X, Zhou Y, Zhao Y, Du Q, Chen J, Mao X, Wang F, Tu B. Analysis of Halophilic Phenotypic Variation and Cytotoxicity of Vibrio parahaemolyticus from Different Sources. Pathogens. 2025; 14(2):182. https://doi.org/10.3390/pathogens14020182

Chicago/Turabian Style

Gu, Jingyue, Xin Dong, Yunqian Zhou, Ying Zhao, Qiang Du, Jia Chen, Xujian Mao, Fengming Wang, and Bowen Tu. 2025. "Analysis of Halophilic Phenotypic Variation and Cytotoxicity of Vibrio parahaemolyticus from Different Sources" Pathogens 14, no. 2: 182. https://doi.org/10.3390/pathogens14020182

APA Style

Gu, J., Dong, X., Zhou, Y., Zhao, Y., Du, Q., Chen, J., Mao, X., Wang, F., & Tu, B. (2025). Analysis of Halophilic Phenotypic Variation and Cytotoxicity of Vibrio parahaemolyticus from Different Sources. Pathogens, 14(2), 182. https://doi.org/10.3390/pathogens14020182

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop