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Article

Poor Adherence to the Screening-Based Strategy of Group B Streptococcus Despite Colonization of Pregnant Women in Greece

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School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece
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Department of Pediatrics, General Hospital of Sparta, 23100 Sparta, Greece
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Department of Pediatrics, Iaso Hospital, 15123 Athens, Greece
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2nd Department of Obstetrics and Gynecology, School of Medicine, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, Greece
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3rd Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece
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2nd Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Children’s Hospital “Pan. & Aglaia Kyriakou”, 11527 Athens, Greece
*
Author to whom correspondence should be addressed.
Academic Editor: Kirsty Le Doare
Pathogens 2021, 10(4), 418; https://doi.org/10.3390/pathogens10040418
Received: 19 February 2021 / Revised: 17 March 2021 / Accepted: 28 March 2021 / Published: 1 April 2021
(This article belongs to the Special Issue Group B-Streptococcus (GBS))
Group B streptococcus (GBS) is a leading cause of serious neonatal infections. Maternal GBS colonization is associated with early- and late-onset neonatal disease (EOD/LOD). In Greece, a screening-based strategy is recommended, in which concurrent vaginal-rectal cultures should be obtained between 36 0/7 and 37 6/7 weeks’ gestation. We sought to examine the level of adherence to the GBS screening guidelines and estimate the prevalence of GBS colonization among pregnant women. Although in Greece the screening-based strategy is followed, we also examined known EOD risk factors and linked them to GBS colonization. A cross-sectional study of 604 women postpartum in three hospitals and maternity clinics was conducted. Following written informed consent, data were collected via a short self-completed questionnaire and review of patients’ records. In 34.6% of the enrolled pregnant women, no culture had been taken. Of the remaining, 12.8% had proper vaginal-rectal sample collections. The overall maternal colonization rate was 9.6%. At least one risk factor for EOD was identified in 12.6% of participants. The presence of risk factors was associated with positive cultures (p = 0.014). The rate of culture collection did not differ between women with or without an EOD risk factor. Adherence to a universal screening of pregnant women with vaginal-rectal cultures was poor. Despite probable underestimation of GBS carrier status, almost 1 in 10 participants were GBS positive during pregnancy. Screening of women with risk factors for EOD should, at least, be prioritized to achieve prevention and prompt intervention of EOD. View Full-Text
Keywords: GBS; maternal carrier status; adherence; culture; pregnancy; risk factors GBS; maternal carrier status; adherence; culture; pregnancy; risk factors
MDPI and ACS Style

Berikopoulou, M.M.; Pana, A.; Liakopoulou-Tsitsipi, T.; Vlahos, N.F.; Papaevangelou, V.; Soldatou, A. Poor Adherence to the Screening-Based Strategy of Group B Streptococcus Despite Colonization of Pregnant Women in Greece. Pathogens 2021, 10, 418. https://doi.org/10.3390/pathogens10040418

AMA Style

Berikopoulou MM, Pana A, Liakopoulou-Tsitsipi T, Vlahos NF, Papaevangelou V, Soldatou A. Poor Adherence to the Screening-Based Strategy of Group B Streptococcus Despite Colonization of Pregnant Women in Greece. Pathogens. 2021; 10(4):418. https://doi.org/10.3390/pathogens10040418

Chicago/Turabian Style

Berikopoulou, Maria M., Aikaterini Pana, Theodota Liakopoulou-Tsitsipi, Nikos F. Vlahos, Vasiliki Papaevangelou, and Alexandra Soldatou. 2021. "Poor Adherence to the Screening-Based Strategy of Group B Streptococcus Despite Colonization of Pregnant Women in Greece" Pathogens 10, no. 4: 418. https://doi.org/10.3390/pathogens10040418

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