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Review

The Role of Lipid Metabolism in Influenza A Virus Infection

by 1, 1 and 2,*
1
Key Laboratory of Animal Epidemiology, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
2
College of Life Science and Basic Medicine/Center for Biotechnology Research, Xinxiang University, Xinxiang 453003, China
*
Author to whom correspondence should be addressed.
Academic Editor: Pawel Zmora
Pathogens 2021, 10(3), 303; https://doi.org/10.3390/pathogens10030303
Received: 28 January 2021 / Revised: 25 February 2021 / Accepted: 3 March 2021 / Published: 5 March 2021
(This article belongs to the Collection Advanced Research on Avian Influenza Virus (AIV))
Influenza A virus (IAV) is an important zoonotic pathogen that can cause disease in animals such as poultry and pigs, and it can cause infection and even death in humans, posing a serious threat to public health. IAV is an enveloped virus that relies on host cell metabolic systems, especially lipid metabolism systems, to complete its life cycle in host cells. On the other side, host cells regulate their metabolic processes to prevent IAV replication and maintain their normal physiological functions. This review summarizes the roles of fatty acid, cholesterol, phospholipid and glycolipid metabolism in IAV infection, proposes future research challenges, and looks forward to the prospective application of lipid metabolism modification to limit IAV infection, which will provide new directions for the development of anti-influenza drugs. View Full-Text
Keywords: influenza A virus (IAV); host cell; lipid metabolism; replication influenza A virus (IAV); host cell; lipid metabolism; replication
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MDPI and ACS Style

Zhou, Y.; Pu, J.; Wu, Y. The Role of Lipid Metabolism in Influenza A Virus Infection. Pathogens 2021, 10, 303. https://doi.org/10.3390/pathogens10030303

AMA Style

Zhou Y, Pu J, Wu Y. The Role of Lipid Metabolism in Influenza A Virus Infection. Pathogens. 2021; 10(3):303. https://doi.org/10.3390/pathogens10030303

Chicago/Turabian Style

Zhou, Yong, Juan Pu, and Yuping Wu. 2021. "The Role of Lipid Metabolism in Influenza A Virus Infection" Pathogens 10, no. 3: 303. https://doi.org/10.3390/pathogens10030303

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