Wood-frame walls in cold climates are traditional constructed with a vapour barrier that also constitutes the air-tightness layer. Polyethylene foil as a vapour barrier is likely used; however, other building materials can be used to obtain correspondingly sufficient properties. 1D hygrothermal simulations were conducted for a wood-frame structure to investigate the wind–vapour barrier ratio, and if the vapour barrier of polyethylene foil could be omitted and replaced by other materials. The results were postprocessed using the VTT mould model. The results showed how wood-frame walls can be designed with respect to internal humidity class and diffusion resistance divided into three categories: no risk for mould growth, needs further investigation, and is not performing well as the risk for mould growth is present. For internal humidity classes 1–3, the ratio between wind and vapour barrier must be about 1:5, and 1:10 for classes 4 and 5 to be on the safe side. Simulations were performed for the climate of Lund, Sweden, which were used to simulate climate in Denmark too. Nevertheless, the results are related to climate data and, thus, the location.
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