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Review

Allograft Prosthesis Composite (APC) for Proximal Humeral Bone Loss: Outcomes and Perspectives

by
Pietro Gregori
1,2,
Giovanni Perricone
1,2,
Edoardo Franceschetti
1,2,*,
Giancarlo Giurazza
1,2,
Giuseppe Francesco Papalia
1,2,
Pierangelo Zà
1,2 and
Rocco Papalia
1,2
1
Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 00128 Roma, Italy
2
Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128 Roma, Italy
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2023, 13(9), 1301; https://doi.org/10.3390/jpm13091301
Submission received: 4 July 2023 / Revised: 17 August 2023 / Accepted: 20 August 2023 / Published: 25 August 2023
(This article belongs to the Special Issue Personalized Management in Orthopedics and Traumatology)

Abstract

(1) Background: Allograft prosthetic composite (APC) represents one of the techniques used for reconstruction in large proximal humeral bone deficits. The present systematic review aimed at summarizing the state of the art of the technique and analyzing its outcomes. (2) Methods: The PRISMA guidelines were followed to perform this systematic review. A systematic electronic search was performed using PubMed (MEDLINE), EMBASE, and the Cochrane Library databases. All the studies analyzing the rates of allograft prosthesis composite were pooled, and the data were extracted and analyzed. (3) Results: A total of 10 studies were eligible for inclusion in this systematic review for a total of 239 patients. The rate of patient satisfaction with surgery was reported in 7 studies with a mean of 86.4% ± 13.64. The mean constant score was 45.7 ± 3.51, the mean ASES score was 63.58 ± 8.37, and the mean SST was 4.6 ± 1.04. The mean revision rate observed was 10.32% ± 3.63 and the mean implant survival was 83.66% ± 14.98. (4) Conclusions: Based on the currently available data, allograft prosthesis composite represents a valuable option for the reconstruction of proximal humeral deficits. All studies analyzed showed the favorable impact of this surgical technique on clinical outcomes and patient satisfaction.
Keywords: shoulder replacement; shoulder revision surgery; allograft prosthesis composite; APC; humeral allograft; APC results shoulder replacement; shoulder revision surgery; allograft prosthesis composite; APC; humeral allograft; APC results

Share and Cite

MDPI and ACS Style

Gregori, P.; Perricone, G.; Franceschetti, E.; Giurazza, G.; Papalia, G.F.; Zà, P.; Papalia, R. Allograft Prosthesis Composite (APC) for Proximal Humeral Bone Loss: Outcomes and Perspectives. J. Pers. Med. 2023, 13, 1301. https://doi.org/10.3390/jpm13091301

AMA Style

Gregori P, Perricone G, Franceschetti E, Giurazza G, Papalia GF, Zà P, Papalia R. Allograft Prosthesis Composite (APC) for Proximal Humeral Bone Loss: Outcomes and Perspectives. Journal of Personalized Medicine. 2023; 13(9):1301. https://doi.org/10.3390/jpm13091301

Chicago/Turabian Style

Gregori, Pietro, Giovanni Perricone, Edoardo Franceschetti, Giancarlo Giurazza, Giuseppe Francesco Papalia, Pierangelo Zà, and Rocco Papalia. 2023. "Allograft Prosthesis Composite (APC) for Proximal Humeral Bone Loss: Outcomes and Perspectives" Journal of Personalized Medicine 13, no. 9: 1301. https://doi.org/10.3390/jpm13091301

APA Style

Gregori, P., Perricone, G., Franceschetti, E., Giurazza, G., Papalia, G. F., Zà, P., & Papalia, R. (2023). Allograft Prosthesis Composite (APC) for Proximal Humeral Bone Loss: Outcomes and Perspectives. Journal of Personalized Medicine, 13(9), 1301. https://doi.org/10.3390/jpm13091301

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