Next Article in Journal
Comment on Rosenzweig et al. Very Low Prostate PET/CT PSMA Uptake May Be Misleading in Staging Radical Prostatectomy Candidates. J. Pers. Med. 2022, 12, 410
Next Article in Special Issue
Novel Biomarkers of Renal Dysfunction and Congestion in Heart Failure
Previous Article in Journal
A Comprehensive Approach to Predicting the Outcomes of Transsphenoidal Endoscopic Adenomectomy in Patients with Cushing’s Disease
Previous Article in Special Issue
Severe Aortic Valve Stenosis and Pulmonary Hypertension: A Systematic Review of Non-Invasive Ways of Risk Stratification, Especially in Patients Undergoing Transcatheter Aortic Valve Replacement
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JPM
Volume 12
Issue 5
10.3390/jpm12050799
jpm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Biomarkers of Myocardial Injury and Remodeling in Heart Failure

by
Barbara Ponikowska
1,*,
Gracjan Iwanek
2,*,
Agata Zdanowicz
2,
Szymon Urban
2,
Robert Zymliński
2,
Piotr Ponikowski
2 and
Jan Biegus
2
1
Student Scientific Organization, Wroclaw Medical University, 50-556 Wroclaw, Poland
2
Institute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland
*
Authors to whom correspondence should be addressed.
J. Pers. Med. 2022, 12(5), 799; https://doi.org/10.3390/jpm12050799
Submission received: 13 April 2022 / Revised: 8 May 2022 / Accepted: 13 May 2022 / Published: 16 May 2022
(This article belongs to the Special Issue Novel Biomarkers for Acute and Chronic Heart Failure)
Browse Figure
Review Reports Versions Notes

Abstract

With its complicated pathophysiology, high incidence and prevalence, heart failure remains a major public concern. In hopes of improving diagnosis, treatment and prognosis, the utility of many different biomarkers is researched vigorously around the world. In this review, biomarkers of myocardial remodeling and fibrosis (galectin-3, soluble isoform of suppression of tumorigenicity 2, matrix metalloproteinases, osteopontin, interleukin-6, syndecan-4, myostatin, procollagen type I C-terminal propeptide, procollagen type III N-terminal propeptide, vascular endothelial growth factor, nitric oxidase synthetase and asymmetric dimethylarginine), myocyte injury (heart-type fatty acid-binding protein, glutathione S-transferase P1 and heat shock protein 60), as well as iron metabolism (ferritin, transferrin saturation, soluble transferrin receptor and hepcidin), are considered in terms of possible clinical applicability and significance. Our short review consists of a summary of the aforementioned cardiovascular biomarkers’ clinical relevance and perspectives.
Keywords: heart failure; biomarkers; remodeling; heart injury heart failure; biomarkers; remodeling; heart injury
Graphical Abstract

Share and Cite

MDPI and ACS Style

Ponikowska, B.; Iwanek, G.; Zdanowicz, A.; Urban, S.; Zymliński, R.; Ponikowski, P.; Biegus, J. Biomarkers of Myocardial Injury and Remodeling in Heart Failure. J. Pers. Med. 2022, 12, 799. https://doi.org/10.3390/jpm12050799

AMA Style

Ponikowska B, Iwanek G, Zdanowicz A, Urban S, Zymliński R, Ponikowski P, Biegus J. Biomarkers of Myocardial Injury and Remodeling in Heart Failure. Journal of Personalized Medicine. 2022; 12(5):799. https://doi.org/10.3390/jpm12050799

Chicago/Turabian Style

Ponikowska, Barbara, Gracjan Iwanek, Agata Zdanowicz, Szymon Urban, Robert Zymliński, Piotr Ponikowski, and Jan Biegus. 2022. "Biomarkers of Myocardial Injury and Remodeling in Heart Failure" Journal of Personalized Medicine 12, no. 5: 799. https://doi.org/10.3390/jpm12050799

APA Style

Ponikowska, B., Iwanek, G., Zdanowicz, A., Urban, S., Zymliński, R., Ponikowski, P., & Biegus, J. (2022). Biomarkers of Myocardial Injury and Remodeling in Heart Failure. Journal of Personalized Medicine, 12(5), 799. https://doi.org/10.3390/jpm12050799

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop