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Article

Prevalence of Pulmonary Hypertension in an Unselected Community-Based Population: A Retrospective Echocardiographic Study—RES-PH Study

1
Department of Clinical and Experimental Medicine, University of Messina, 98100 Messina, Italy
2
UTIC and Cardiology, Hospital “Pugliese-Ciaccio” of Catanzaro, 88100 Catanzaro, Italy
3
Unit of Emergency Medicine, Irccs Neurolesi Bonino Pulejo, 98100 Messina, Italy
4
Internal Medicine Unit, Azienda ULSS 5 Polesana—Rovigo General Hospital, 45100 Rovigo, Italy
5
Department of Medical Translational Sciences, Division of Cardiology, Monaldi Hospital, University of Campania “Luigi Vanvitelli”, 80100 Naples, Italy
6
Department of Medicine, Buonconsiglio Fatebenefratelli Hospital, 80122 Naples, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Konstantinos Tziomalos
J. Pers. Med. 2021, 11(6), 489; https://doi.org/10.3390/jpm11060489
Received: 10 May 2021 / Revised: 21 May 2021 / Accepted: 26 May 2021 / Published: 31 May 2021
(This article belongs to the Special Issue Cardiovascular Disease Prevention in the Era of Personalized Medicine)
Introduction. The actual prevalence of pulmonary hypertension (PH) in Italy is unknown. Echocardiography is useful in the screening of patients with suspected PH by estimation of the pulmonary artery systolic pressure (PASP) from the regurgitant tricuspid flow velocity evaluation, according to the simplified Bernoulli equation. Objectives. We aimed to evaluate the frequency of suspected PH among unselected patients. Methods. We conducted a retrospective cross-sectional database search of 7005 patients, who underwent echocardiography, to estimate the prevalence of PH, between January 2013 and December 2014. Medical and echocardiographic data were collected from a stratified etiological group of PH, using criteria of the European Society of Cardiology classifications. Results. The mean age of the study population was 57.1 ± 20.5 years, of which 55.3% were male. The prevalence of intermediate probability of PH was 8.6%, with nearly equal distribution between men and women (51.3 vs. 48.7%; p = 0.873). The prevalence of high probability of PH was 4.3%, with slightly but not significant higher prevalence in female patients (43.2 vs. 56.8%; p = 0.671). PH is predominant in patients with chronic obstructive pulmonary disease (COPD) or left ventricle (LV) systolic dysfunction and related with age. PASP was significantly linked with left atrial increase and left ventricular ejection fraction. In addition, an increased PASP was related to an enlargement of the right heart chamber. Conclusions. PH has a frequency of 4.3% in our unselected population, but the prevalence may be more relevant in specific subgroups. A larger epidemiological registry could be an adequate strategy to increase quality control and identify weak points in the evaluation and treatment of these patients. View Full-Text
Keywords: echocardiography; pulmonary hypertension; pulmonary artery systolic pressure; unselected population echocardiography; pulmonary hypertension; pulmonary artery systolic pressure; unselected population
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MDPI and ACS Style

Imbalzano, E.; Vatrano, M.; Lo Gullo, A.; Orlando, L.; Mazza, A.; Ciconte, V.A.; Russo, V.; Giuffrida, C.; Di Micco, P.; Versace, A.G.; Mandraffino, G.; Squadrito, G. Prevalence of Pulmonary Hypertension in an Unselected Community-Based Population: A Retrospective Echocardiographic Study—RES-PH Study. J. Pers. Med. 2021, 11, 489. https://doi.org/10.3390/jpm11060489

AMA Style

Imbalzano E, Vatrano M, Lo Gullo A, Orlando L, Mazza A, Ciconte VA, Russo V, Giuffrida C, Di Micco P, Versace AG, Mandraffino G, Squadrito G. Prevalence of Pulmonary Hypertension in an Unselected Community-Based Population: A Retrospective Echocardiographic Study—RES-PH Study. Journal of Personalized Medicine. 2021; 11(6):489. https://doi.org/10.3390/jpm11060489

Chicago/Turabian Style

Imbalzano, Egidio, Marco Vatrano, Alberto Lo Gullo, Luana Orlando, Alberto Mazza, Vincenzo A. Ciconte, Vincenzo Russo, Clemente Giuffrida, Pierpaolo Di Micco, Antonio G. Versace, Giuseppe Mandraffino, and Giovanni Squadrito. 2021. "Prevalence of Pulmonary Hypertension in an Unselected Community-Based Population: A Retrospective Echocardiographic Study—RES-PH Study" Journal of Personalized Medicine 11, no. 6: 489. https://doi.org/10.3390/jpm11060489

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