Liquid Biopsy in Gastrointestinal Cancers
AbstractLiquid biopsy is the sampling of any biological fluid in an effort to enrich and analyze a tumor’s genetic material. Peripheral blood remains the most studied liquid biopsy material, with circulating tumor cells (CTC’s) and circulating tumor DNA (ctDNA) allowing the examination and longitudinal monitoring of a tumors genetic landscape. With applications in cancer screening, prognostic stratification, therapy selection and disease surveillance, liquid biopsy represents an exciting new paradigm in the field of cancer diagnostics and offers a less invasive and more comprehensive alternative to conventional tissue biopsy. Here, we examine liquid biopsies in gastrointestinal cancers, specifically colorectal, gastric, and pancreatic cancers, with an emphasis on applications in diagnostics, prognostics and therapeutics. View Full-Text
Share & Cite This Article
Saini, A.; Pershad, Y.; Albadawi, H.; Kuo, M.; Alzubaidi, S.; Naidu, S.; Knuttinen, M.-G.; Oklu, R. Liquid Biopsy in Gastrointestinal Cancers. Diagnostics 2018, 8, 75.
Saini A, Pershad Y, Albadawi H, Kuo M, Alzubaidi S, Naidu S, Knuttinen M-G, Oklu R. Liquid Biopsy in Gastrointestinal Cancers. Diagnostics. 2018; 8(4):75.Chicago/Turabian Style
Saini, Aman; Pershad, Yash; Albadawi, Hassan; Kuo, Malia; Alzubaidi, Sadeer; Naidu, Sailendra; Knuttinen, M-Grace; Oklu, Rahmi. 2018. "Liquid Biopsy in Gastrointestinal Cancers." Diagnostics 8, no. 4: 75.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.