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Diagnostics 2018, 8(4), 84;

Quiescent-Interval Single-Shot Magnetic Resonance Angiography

Division of Vascular and Interventional Radiology, Laboratory for Minimally Invasive Therapeutics, Mayo Clinic, Phoenix, Arizona 85054, USA
Author to whom correspondence should be addressed.
Received: 2 November 2018 / Revised: 15 December 2018 / Accepted: 15 December 2018 / Published: 18 December 2018
(This article belongs to the Special Issue Imaging-Based Diagnostics in Interventional Medicine)
Full-Text   |   PDF [678 KB, uploaded 18 December 2018]   |  


Lower extremity peripheral arterial disease (PAD) is a chronic, debilitating disease with a significant global burden. A number of diagnostic imaging techniques exist, including computed tomography angiography (CTA) and contrast-enhanced magnetic resonance angiography (CEMRA), to aid in PAD diagnosis and subsequent treatment planning. Due to concerns of renal toxicity or nephrogenic systemic fibrosis (NSF) for iodinated and gadolinium-based contrasts, respectively, a number of non-enhanced MRA (NEMRA) protocols are being increasingly used in PAD diagnosis. These techniques, including time of flight and phase contrast MRA, have previously demonstrated poor image quality, long acquisition times, and/or susceptibility to artifacts when compared to existing contrast-enhanced techniques. In recent years, Quiescent-Interval Single-Shot (QISS) MRA has been developed to overcome these limitations in NEMRA methods, with promising results. Here, we review the various screening and diagnostic tests currently used for PAD. The various NEMRA protocols are discussed, followed by a comprehensive review of the literature on QISS MRA to date. A particular emphasis is placed on QISS MRA feasibility studies and studies comparing the diagnostic accuracy and image quality of QISS MRA versus other diagnostic imaging techniques in PAD. View Full-Text
Keywords: quiescent-interval single-shot; non-enhanced MRA; MRA; peripheral arterial disease quiescent-interval single-shot; non-enhanced MRA; MRA; peripheral arterial disease

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Saini, A.; Wallace, A.; Albadawi, H.; Naidu, S.; Alzubaidi, S.; Knuttinen, M.G.; Panda, A.; Oklu, R. Quiescent-Interval Single-Shot Magnetic Resonance Angiography. Diagnostics 2018, 8, 84.

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