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Volume 14
Issue 3
10.3390/diagnostics14030246
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Case Report

Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature

by
Valentin Nicolae Varlas
1,2,
Eliza Maria Cloțea
2,
Roxana Georgiana Varlas
2,
Anca Pop
1,3,
Ovidiu Peneș
1,4,*,
Dragoș Crețoiu
5,6,*,
Vlad Dima
7,* and
Laura Bălănescu
1,8
1
Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
2
Department of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011132 Bucharest, Romania
3
Department of Clinical Laboratory, Food Safety, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020945 Bucharest, Romania
4
Department of Intensive Care, University Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu St., 020021 Bucharest, Romania
5
Fetal Medicine Excellence Research Center, Alessandrescu-Rusescu National Institute for Mother and Child Health, 020395 Bucharest, Romania
6
Department of Genetics, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania
7
Department of Neonatology, Filantropia Clinical Hospital, 011132 Bucharest, Romania
8
Department of Pediatric Surgery, Children Emergency Hospital “Grigore Alexandrescu”, 011743 Bucharest, Romania
*
Authors to whom correspondence should be addressed.
Diagnostics 2024, 14(3), 246; https://doi.org/10.3390/diagnostics14030246
Submission received: 7 November 2023 / Revised: 11 January 2024 / Accepted: 22 January 2024 / Published: 24 January 2024
(This article belongs to the Special Issue Fetal Medicine: From Basic Science to Prenatal Diagnosis and Therapy)
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Abstract

Immature sacrococcygeal teratoma represents a histological form with rapid tumor growth, a risk of premature birth, an enhanced rate of complications, an increased risk of recurrence, and a higher mortality rate than the mature type. Thus, prenatal diagnosis of immature forms would significantly improve the prognosis of these cases. To this end, we performed an extensive literature review on the diagnosis, therapeutic management, and follow-up of immature teratomas. Regarding this medical conduct, we also presented our case. In conclusion, the early identification of immature sacrococcygeal teratomas with or without other associated structural abnormalities and their correct therapeutic approach are basic principles for a favorable evolution of these cases.
Keywords: sacrococcygeal teratoma; immature histologic type; prenatal diagnosis; therapeutic approach; recurrence; prognostic sacrococcygeal teratoma; immature histologic type; prenatal diagnosis; therapeutic approach; recurrence; prognostic

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MDPI and ACS Style

Varlas, V.N.; Cloțea, E.M.; Varlas, R.G.; Pop, A.; Peneș, O.; Crețoiu, D.; Dima, V.; Bălănescu, L. Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature. Diagnostics 2024, 14, 246. https://doi.org/10.3390/diagnostics14030246

AMA Style

Varlas VN, Cloțea EM, Varlas RG, Pop A, Peneș O, Crețoiu D, Dima V, Bălănescu L. Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature. Diagnostics. 2024; 14(3):246. https://doi.org/10.3390/diagnostics14030246

Chicago/Turabian Style

Varlas, Valentin Nicolae, Eliza Maria Cloțea, Roxana Georgiana Varlas, Anca Pop, Ovidiu Peneș, Dragoș Crețoiu, Vlad Dima, and Laura Bălănescu. 2024. "Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature" Diagnostics 14, no. 3: 246. https://doi.org/10.3390/diagnostics14030246

APA Style

Varlas, V. N., Cloțea, E. M., Varlas, R. G., Pop, A., Peneș, O., Crețoiu, D., Dima, V., & Bălănescu, L. (2024). Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature. Diagnostics, 14(3), 246. https://doi.org/10.3390/diagnostics14030246

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